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A Historical Perspective On Evidence Based Immunology

Author: Edward J. Moticka
Publisher: Newnes
ISBN: 0123983754
Size: 17.88 MB
Format: PDF
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A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells

Immunologie In Deutschland

Author: Deutsche Gesellschaft für Immunologie
Publisher: be.bra wissenschaft verlag
ISBN: 394768603X
Size: 11.69 MB
Format: PDF, Mobi
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Das 50-jährige Jubiläum der Deutschen Gesellschaft für Immunologie bietet die einmalige Chance, sowohl die wissenschaftlichen Triumphe als auch die Entwicklung des Fachs Immunologie in der deutschen Forschungslandschaft von der Vergangenheit bis in die Gegenwart näher zu beleuchten. In diesem Band wird die Entwicklung der immunologischen Fachgesellschaften in der ehemaligen BRD und DDR nach 1945 und deren Zusammenführung nach der Wiedervereinigung in den Blick genommen. Ausführlich dargestellt wird aber auch der Zeitraum von der Entdeckung und der ersten klinischen Anwendung der Antikörper durch Emil von Behring, Shibasaburo Kitasato und Paul Ehrlich über den unglaublichen Niedergang der Immunologie mit dem Exodus hervorragender klinischer Immunologen nach 1930 bis hin zur Entwicklung der Hybridomtechnik durch Georges Koehler und César Milstein im Jahre 1975. Mit zahlreichen Abbildungen.


Author: Anil Kumar Anal
Publisher: CRC Press
ISBN: 1351643630
Size: 49.57 MB
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This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to engineer the behavior of molecules at the nanoscale, are also explored and analyzed. The aim of the text is to provide the reader with broader knowledge of biological methods for signal transduction and molecular recognitions systems and how they can be replicated in bio-sensing applications. The reader will learn the basic structures and interactions of biomacromolecules for developing biocompatible and eco-friendly devices.


Author: Francesco Chiappelli
Publisher: Springer Science & Business Media
ISBN: 9781441994950
Size: 54.75 MB
Format: PDF, ePub, Docs
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Osteoimmunology pertains to the study of the relationship between the bones, particularly the bone marrow, and the immune system. This monograph pursues the best available evidence, by means of research synthesis, for the characterization of the physiological relevance and pathological implications of the inter-connectedness between the skeletal and the immune system. Research will be discussed that highlights the associated role of the circulatory, nervous and endocrine systems, as well as proteomic and genomic pathways and signatures. Emphasis is given that domain of medicine that relates to the oral cavity, its diseases and their systemic sequelae. This monograph arises from observations that have suggested that the skeletal system and the immune system are intimately intertwined. Chronic inflammatory reactions subsequent to an excessive immune reaction can damage the bones, as in rheumatoid arthritis (RA), osteoporosis, patients seropositive for the human immunodeficiency virus (HIV)-1 and with signs and symptoms of the acquired immune deficiency syndrome (AIDS), and bone cancer. Bones – in particular the bone marrow – are one of the primary locations in which cells of the immune system mature. In brief, this monograph begins to answer a range of questions, such as, what is osteoimmunology all about?, does the immune system and its components affect bone development?, how do stress hormones impact upon the pathophysiology of bone-immune interactions?, can the scientific process of research synthesis, obtain the best available evidence for treatment of diseases involving the bone-immune entity (i.e., osteo immunopathologies) means of evidence-based clinical decision-making directed at the treatment of osteoimmune pathologies?

Perikonzeptionelle Frauenheilkunde

Author: Christian Gnoth
Publisher: Springer-Verlag
ISBN: 3642380239
Size: 30.56 MB
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Bis zu 25% aller Schwangerschaften gelten heutzutage als Risikoschwangerschaft. Deshalb sind bei Frauen mit speziellen Grunderkrankungen wie z.B. bei Diabetes mellitus, früheren Fehlgeburten, Herzerkrankungen schon bei der Planung und später während der Schwangerschaft besondere Maßnahmen zu beachten. Ein Praxisbuch für alle in der Beratung und Betreuung von Schwangeren und Paaren mit Kinderwunsch Tätigen. Es gibt konkrete und praxisrelevante Handlungsempfehlungen auf Basis der aktuellen Studienlage: Verhütung heute - Empfängnis morgen Die natürliche Fertilität: Chancen, Diagnostik, Optimierung Was tun bei Subfertilität? Medizinische Aspekte der gesunden Lebensführung Die Begleitung der Risikopatientin mit Vorerkrankung: vor und während der Schwangerschaft Prophylaxe von Fehlgeburt, Gestose und Frühgeburt Die Herausgeber und Autoren haben alle wichtigen Informationen zusammengetragen, um Frauen sicher zu beraten, zu betreuen und kompetent Verantwortung zu übernehmen. Stimmen aus gynäkologischen Kreisen: - Hochinteressant. Das Thema ist von größter Bedeutung...!

Life Cycle Nutrition An Evidence Based Approach

Author: Sari Edelstein
Publisher: Jones & Bartlett Publishers
ISBN: 1449632238
Size: 64.31 MB
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Life Cycle Nutrition: An Evidence-Based Approach uses the latest evidence-based research to explore the nutritional foundations and the growth, development and normal functioning of individuals through each stage of life. It covers the physiological, biochemical, sociological, and developmental factors that affect nutrient requirements and recommendations at various stages of the life cycle.

Bacteriophage Applications Historical Perspective And Future Potential

Author: Jessica Nicastro
Publisher: Springer
ISBN: 3319457918
Size: 48.89 MB
Format: PDF, Kindle
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This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries. Since the discovery of phages and the advent of phage display systems, considerable attention has been focused on the development of novel therapeutic and industrial applications. Recent studies combine the genomic flexibility of phages with phage display systems in order to generate modified phages for targeted delivery.

Allergy And Asthma Practical Diagnosis And Management

Author: Massoud Mahmoudi
Publisher: McGraw Hill Professional
ISBN: 9780071593533
Size: 37.97 MB
Format: PDF, ePub
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Clear, authoritative guidance for your day-to-day allergy and asthma practice Allergy and Asthma: Practical Diagnosis and Management is a concise guide that puts the most salient insights in allergy medicine right at your fingertips. Written by a leading allergy clinician, along with 30 nationally recognized expert contributors, this resource is perfect for front-line general practitioners, especially primary care physicians and allied health care providers. Inside, you'll find the most clinically relevant information on the pathophysiology, diagnosis, treatment, and prevention of all major allergic disorders. Features Need-to-know coverage that spans the entire scope of adult allergy and asthma-geared for real world medical practice A timely look at occupational allergies and allergies linked to unhealthy environments Organization by specific organ, which guides you to diagnostic and therapeutic solutions quickly and easily Essential chapters on the principles of diagnosis and on medications used in the management of simple and complex allergy Coverage of new complementary and alternative medicine techniques in the management of allergic disorders Over 100 outstanding illustrations Key concepts, management protocols, and recent references that deliver s a highly accessible overview of today's allergy practice


Author: Alfred E. Chang
Publisher: Springer Science & Business Media
ISBN: 9780387310565
Size: 61.73 MB
Format: PDF
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Title consistently uses the evidence-based approach Evidence-based tables make documentation of care plan easy Interdisciplinary orientation – all aspects of patient care are covered Only book that involves experts from the entire range of cancer treatment in the fields of medical, surgical and radiation oncology Includes hot topics such as prevention and breast cancer Offers ground-breaking sections on the latest research and clinical applications in cancer survivorship Chapter on PET addresses imaging issues and how to get the best results Most comprehensive sections on the biology and epidemiology of cancer as compared to competitors