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Advances In Heterocyclic Chemistry

Author:
Publisher: Academic Press
ISBN: 0080576494
Size: 78.44 MB
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Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Every fifth volume ofAdvances in Heterocyclic Chemistry contains a cumulative subject index. A selection of topics covered in Volume 62 Synthesis possibilities in N-Fluoropyridinium salts An updated review of Pyran Chemistry The organic chemistry and synthesis of Tetrathia- and tetraselena-fulvalenes A review of the classes of five-membered heterocyclic rings containing two sulfur and two nitrogen atoms, both as anionic and radical species

Progress In Heterocyclic Chemistry

Author: Gordon W. Gribble
Publisher:
ISBN: 9780080454085
Size: 69.21 MB
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This is the 19th annual volume of 'Progress in Heterocyclic Chemistry', which covers the literature published during 2006. As with previous volumes in the series, Volume 19 will enable the reader to keep abreast of developments in heterocyclic chemistry in an effortless way.

Fluorine In Organic Chemistry

Author: Richard D. Chambers
Publisher: CRC Press
ISBN: 9780849317903
Size: 58.45 MB
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Replacing hydrogen with fluorine in organic molecules can profoundly influence their chemical and physical properties, leading to a range of chemical compounds, from Prozac to Teflon, which rely on organic fluorine chemistry for their useful and highly desirable properties. Fluorine in Organic Chemistry introduces its subject by discussing the chemical properties and electronic effects of fluorocarbon systems. Subsequent chapters detail the most efficient methods for the preparation and synthesis of partially, selectively, and highly fluorinated systems, from electrochemical flourination, to the addition of fluorine to olefins and aceytylenes. Other topics include: the characteristics of fluorocarbon groups in terms of ions, acids, and bases; substitution effects of fluorocarbon groups on nucleophilic displacement; elimination reactions; flouroalkane, functional, and polyfluoroaromatic compounds; fluorine in biochemistry; and organometallic reagents. With applications that extend from pharmaceuticals to fine and specialty chemicals to polymers, Fluorine in Organic Chemistry is an excellent reference for all organic chemists.

Heterocyclic Chemistry

Author: John A. Joule
Publisher: John Wiley & Sons
ISBN: 1118681649
Size: 66.49 MB
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This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.

Green Techniques For Organic Synthesis And Medicinal Chemistry

Author: Wei Zhang
Publisher: John Wiley & Sons
ISBN: 0470711515
Size: 78.48 MB
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Green chemistry is a new way of looking at organic synthesis and the design of drug molecules, offering important environmental and economic advantages over traditional synthetic processes. Pharmaceutical companies are increasingly turning to the principles of green chemistry in an effort to reduce waste, reduce costs and develop environmentally benign processes. Green Techniques for Organic Synthesis and Medicinal Chemistry presents an overview of the established and emerging techniques in green organic chemistry, highlighting their applications in medicinal chemistry. The book is divided into four parts: Introduction: Introduces the reader to the toxicology of organic chemicals,their environmental impact, and the concept of green chemistry. Green Catalysis: Covers a variety of green catalytic techniques including organocatalysis, supported catalysis, biocatalysis, fluorous catalysis, and catalytic direct C-H bond activation reactions. Green Synthetic Techniques: Presents a series of new techniques, assessing the green chemistry aspects and limitations (i.e. cost, equipment, expertise). Techniques include reactions in alternative solvents, atom economic multicomponent reactions, microwave and ultrasonic reactions, solid-supported synthesis, fluorous and ionic liquid-based recycling techniques, and flow reactors. Green Techniques in Pharmaceutical Industry: Covers applications of green chemistry concepts and special techniques for medicinal chemistry, including synthesis, analysis, separation, formulation, , and drug delivery. Process and business case studies are included to illustrate the applications in the pharmaceutical industry. Green Techniques for Organic Synthesis and Medicinal Chemistry is an essential resource on green chemistry technologies for academic researchers, R&D professionals and students working in organic chemistry and medicinal chemistry.

Advances In Pesticide Science

Author: H. Geissbühler
Publisher: Elsevier
ISBN: 1483182142
Size: 14.12 MB
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Advances in Pesticide Science: Abstracts and Addendum documents the proceedings of the Fourth International Congress of Pesticide Chemistry held in Zurich on July 24-28, 1978. This book discusses the synthesis of isocoumarins and their biological activities; structure-activity correlations in control of membrane-bound linolenic acid with substituted pyridazinones; and oxidative processes in pesticide transformation. The cardiovascular and neurotoxicity of endosulfan; chemistry and plant growth regulating activity of fusicoccin derivatives and analogs; and pesticide interactions with naturally occurring food components are also elaborated. This compilation likewise covers the techniques for deriving realistic estimates of pesticide intakes; confirmation tests for pesticides based on gas chromatographic techniques; surfactants in flowable formulations; and thin-layer densitometry. This publication is a good reference for biologists and chemists researching on pesticides and its relation to food and the environment.