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Advances In Vasopressin And Oxytocin From Genes To Behaviour To Disease

Author: Rainer Landgraf
Publisher: Elsevier
ISBN: 9780080932477
Size: 30.87 MB
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Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohypophysial system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike. • Comprehensive review of OXT and AVP physiology and behaviour • Each chapter covers a novel aspect of OXT and AVP research and is written by a leading expert • Review articles are ideal for experts and newcomers to the field alike • Discusses fascinating behavioural effects of oxytocin and vasopressin • Summarizes the recent explosion of neuropeptide research, physiology and behaviour, is in one location

Brain Extracellular Matrix In Health And Disease

Author:
Publisher: Elsevier
ISBN: 0444634940
Size: 47.29 MB
Format: PDF, ePub, Docs
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In the central nervous system, extracellular matrix (ECM) molecules, including hyaluronic acid, chondroitin and heparan sulfate proteoglycans, tenascins, reelin and agrin, along with their remodelling enzymes, such as neurotrypsin, neuropsin, plasminogen activators, and metalloproteinases, are secreted by neural and non-neural cells into the extracellular space to form the ECM and signal via ECM receptors. Despite recent advances in the ECM field, the importance of neural ECM for physiological and pathological processes is currently less widely recognized than that of other CNS elements. This book will enlighten recent progress in our understanding of mechanisms by which neural ECM, its receptors and activity-dependent ECM remodeling regulate neural development, synaptic plasticity, and contribute to pathological changes in the brain. In the first part, the roles of ECM signaling and proteolytic modification of ECM in neurogenesis, neural migration, axonal pathfinding, synaptogenesis, synaptic and homeostatic plasticity will be discussed. The second part will focus on the emerging ECM-dependent mechanisms associated with CNS injury, epilepsy, neurodegenerative and neuropsychiatric diseases. For further development of neural ECM field, a very important contribution is the third part of the book, which is devoted to neural ECM-targeting tools and therapeutics. The concluding fourth part will highlight advances in development of artificial ECM and ECM-based systems suitable for multisite recording and stimulation of neural cells. Authors are the leading experts in the field of brain extracellular matrix in health and disease Book covers the most important aspects of brain extracellular matrix in health and disease Interesting for both scientists and clinicians

Music Neurology And Neuroscience Evolution The Musical Brain Medical Conditions And Therapies

Author:
Publisher: Elsevier
ISBN: 0444635521
Size: 22.64 MB
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Did you ever ask whether music makes people smart, why a Parkinson patient's gait is improved with marching tunes, and whether Robert Schumann was suffering from schizophrenia or Alzheimer's disease? This broad but comprehensive book deals with history and new discoveries about music and the brain. It provides a multi-disciplinary overview on music processing, its effects on brain plasticity, and the healing power of music in neurological and psychiatric disorders. In this context, the disorders the plagued famous musicians and how they affected both performance and composition are critically discussed, and music as medicine, as well as music as a potential health hazard are examined. Among the other topics covered are: how music fit into early conceptions of localization of function in the brain, the cultural roots of music in evolution, and the important roles played by music in societies and educational systems. Topic: Music is interesting to almost everybody Orientation: This book looks at music and the brain both historically and in the light of the latest research findings Comprehensiveness: This is the largest and most comprehensive volume on "music and neurology" ever written! Quality of authors: This volume is written by a unique group of real world experts representing a variety of fields, ranging from history of science and medicine to neurology and musicology

Recent Advances In Parkinsons Disease

Author:
Publisher: Elsevier
ISBN: 9780444537515
Size: 57.94 MB
Format: PDF, Kindle
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This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. Different areas of experimental therapeutics and outstanding challenges to PD treatment are presented in a concluding group of articles. Complete overview of hot topics and approaches to current PD research, from molecules, to brain circuits, to clinical and therapeutic applications Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Vasopressin And Oxytocin From Genes To Clinical Applications

Author: D. Poulain
Publisher: Elsevier
ISBN: 9780080522821
Size: 47.87 MB
Format: PDF
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The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system. Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.

Cultural Neuroscience Cultural Influences On Brain Function

Author: Juan Y. Chiao
Publisher: Elsevier
ISBN: 0080952216
Size: 26.81 MB
Format: PDF, ePub
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This volume presents recent empirical advances using neuroscience techniques to investigate how culture influences neural processes underlying a wide range of human abilities, from perception and scene processing to memory and social cognition. It also highlights the theoretical and methodological issues with conducting cultural neuroscience research. Section I provides diverse theoretical perspectives on how culture and biology interact are represented. Sections II –VI is to demonstrate how cultural values, beliefs, practices and experience affect neural systems underlying a wide range of human behavior from perception and cognition to emotion, social cognition and decision-making. The final section presents arguments for integrating the study of culture and the human brain by providing an explicit articulation of how the study of culture can inform the study of the brain and vice versa.

Advances In Brain Vasopressin

Author: I.J.A. Urban
Publisher: Elsevier
ISBN: 9780080862446
Size: 20.44 MB
Format: PDF, ePub
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Advances in Brain Vasopressin elucidates the functions of the regulatory peptide vasopressin in the nervous system, and reviews the current status of this field at different levels. It deals with the cell biology and anatomy of the neurons that produce vasopressin in the brain, and provides an overview on the receptors of vasopressin and the signal transduction pathways that they activate, including the cellular responses that are triggered by vasopressin. Reviews are presented on the modulation of behavior induced by vasopressin in a number of different contexts, such as sex-linked and steroid-dependent behaviors, social behaviors, and learning and memory. Furthermore, the volume deals with several controversial issues in the field by presenting overlapping chapters from different research groups in order to provide the reader with current views. Highly relevant and useful, for those working on this "first" neuropeptide, and for young investigators entering the field, and in addition, shows how important a multidisciplinary approach is to unravelling the function of a neuropeptide in the brain.

Hormones Brain And Behavior Online

Author:
Publisher: Academic Press
ISBN: 008088783X
Size: 45.70 MB
Format: PDF
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Hormones, Brain, and Behavior Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available. * Comprehensive coverage of a growing field of research * Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunites for relating behavior to molecular genetics * Covers an unusual breadth ranging from molecules to ecophysiology, and from basic science to clinical research

Handbook Of Neuroendocrinology

Author: George Fink
Publisher: Academic Press
ISBN: 0123750970
Size: 28.46 MB
Format: PDF, ePub, Mobi
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Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.