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Analysis Of Sterols And Other Biologically Significant Steroids

Author: W. David Nes
Publisher: Elsevier
ISBN: 0323154441
Size: 50.97 MB
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Analysis of Sterols and Other Biologically Significant Steroids provides the fundamental training for the analysis of selected sterols and steroids. The book is composed of chapters that review the spectroscopic and chromatographic properties of certain sterols and steroids. The text also teaches how to isolate and characterize sterols and steroid metabolites of plant, fungal, and insect origin. Lipoprotein analysis and the utilization of physical-analytical techniques are likewise provided. Biochemists, microbiologists, and medical physiologists will find the book useful.

Food Lipids

Author: David B. Min
Publisher: CRC Press
ISBN: 1420046640
Size: 79.72 MB
Format: PDF, ePub
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Maintaining the high standards that made the previous editions such well-respected and widely used references, Food Lipids: Chemistry, Nutrition, and Biotechnology, Third Edition tightens its focus to emphasize lipids from the point of entry into the food supply and highlights recent findings regarding antioxidants and lipid oxidation. Always representative of the current state of lipid science, this edition provides four new chapters reflecting the latest advances in antioxidant research. New chapters include: Polyunsaturated Lipid Oxidation in Aqueous Systems, Tocopherol Stability and the Prooxidant Mechanisms of Oxidized Tocopherols in Lipids, Effects and Mechanisms of Minor Compounds in Oil on Lipid Oxidation, and Total Antioxidant Evaluation and Synergism. The most comprehensive and relevant treatment of food lipids available, this book highlights the role of dietary fats in foods, human health, and disease. Divided into five parts, it begins with the chemistry and properties of food lipids covering nomenclature and classification, extraction and analysis, and chemistry and function. Part II addresses processing techniques including recovery, refining, converting, and stabilizing, as well as chemical interesterification. The third Part has been renamed and expanded to honor the growing data on oxidation and antioxidants. Part IV explores the myriad interactions of lipids in nutrition and health with information on heart disease, obesity, and cancer, and Part V continues with contributions on biotechnology and biochemistry including a chapter on the genetic engineering of crops that produce vegetable oil. Revised and updated with new information and references throughout the text, this third edition of a bestselling industry standard once again draws on the contributions of leading international experts to establish the latest benchmark in the field and provide the platform from which to further advance lipid science.

Analysis Of Sterols

Author: J. Goad
Publisher: Springer Science & Business Media
ISBN: 9400914474
Size: 60.76 MB
Format: PDF, Kindle
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Knowledge is of two kinds. We know a subject ourselves, or we know where we can find information on it Samuel Johnson, 18 April, 1775* Sterols are among the most studied groups of natural products with interest commencing in the 19th century and running to the present. Investigations have embraced the refinement of separation procedures, the development of new analytical techniques and instrumentation for structure elucidation, the unravelling of biosynthetic mechanisms, the determination of the physiological functions of sterols, and the role they play in health and disease. In the past 20-30 years interest in the medical implications of sterol biochemistry, studies on the sterols of plants, algae and fungi, and the identification of the many unusual sterols from marine organisms have proceeded in parallel and somewhat independently. Although the motiva tion and goals for the various lines of investigation have differed widely the researchers working in each of these areas have contributed a wealth of knowledge to the literature relating to the analysis of sterols and many diverse new sterols have been discovered. We conceived this book as a modest attempt to bring together some of this literature in the hope that it may be helpful to newcomers to sterol research. We had originally intended to produce a 'handbook' outlining in detail the protocols to be followed for sterol extraction, chromatography, NMR analysis, etc. in order to identify the components of a sterol mixture.

Molecular Structure And Biological Activity Of Steroids

Author: Martin Bohl
Publisher: CRC Press
ISBN: 1351091700
Size: 72.89 MB
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Molecular Structure and Biological Activity of Steroids focuses on the indentification of steroid structural features that control particular biological effects. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book. Well-established observations and proposed models are presented, summarizing knowledge of molecular features (e.g., steroid backbone structures, side-chain constitutions, substitution sites, configurations, hydrogen-bonding patterns) that can affect steroid action. The book also provides overviews about recent progress in various frontier fields of steroid research, including such areas as sex steroids, glucocorticoids, aromatase inhibitors, vitamin D metabolites, brassinosteroids, neuromuscular blocking agents, and cardiotonic steroids. Molecular Structure and Biological Activity of Steroids is a "must-have" resource for biochemists, pharmacologists, endocrinologists, biophysicists, and others actively involved in steroid research.

R Mpp Encyclopedia Natural Products 1st Edition 2000

Author: Burkhard Fugmann
Publisher: Georg Thieme Verlag
ISBN: 3131795514
Size: 28.76 MB
Format: PDF
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Compiled by German natural products chemist Wolfgang Steglich and his co-editors Burkhard Fugmann and Susanne Lang-Fugmann, RÖMPP Encyclopedia Natural Products provides highly reliable and comprehensive information on the 6,000 most relevant natural substances, including 15,000 cross references and 2,200 formulas. The book contains descriptions of the different substance classes and important analytical methods, comprehensive indices of Latin Species names and molecular formulas as well as a vast amount of cross referencing. It has been compiled by 40 leaders in their respective fields. Written in a clear, consistent style and thoroughly copy edited, this is a must-have reference work for chemists, biochemists working with natural products, researchers in plant protection, pharmacists and medical researchers, biologists working in drug research as well as microbiologists and botanists working on microorganisms, plants or marine organisms, and interested layman.

Olives And Olive Oil In Health And Disease Prevention

Author: Victor R. Preedy
Publisher: Academic Press
ISBN: 9780080922201
Size: 68.41 MB
Format: PDF, Docs
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Long used in sacred ceremonies and associated with good health, the nutritional and health promoting benefits of olives and olive oils have been proven by an ever-increasing body of science. From cardiovascular benefits to anti-microbial, anti-cancer, antioxidant activity and effects on macrophages and aptoptosis to cellular and pathophysiollogical process, olives and olive oils are proving important in many healthful ways. For example, reactive components in olive oils or olive oil by-products have now been isolated and identified. These include tyrosol, hydroxytyrosol, 3,4-dihydroxyphenyl acetic acid elenolic acid and oleuropein. Oleic acid is the main monosaturated fatty acid of olive oil. These have putative protective effects and modulate the biochemistry of a variety of cell types including those of the vascular system. Some but not all components have been characterised by their putative pharmacological properties. It is possible that usage of these aforementioned products may have beneficial application in other disease. However, in order for this cross-fertilization to take place, a comprehensive understanding of olives and olive oils is required. Finding this knowledge in a single volume provides a key resource for scientists in a variety of food an nutritional roles. Key Features: * Explores olives and olive oil from their general aspects to the detailed level of important micro-and micronutrients * Includes coverage of various methodologies for analysis to help scientists and chemists determine the most appropriate option for their own studies, including those of olive-related compounds in other foods * Relates, in a single volume resource, information for food and nutritional chemists, pharmaceutical scientists, nutritionists and dieticians * Presents information in three key categories: General aspects of olives an olive oils; Nutritional, pharmacological and metabolic properties of olives and olive oil; Specific components of olive oil and their effects on tissue and body systems

Quantitative Analysis Of Steroids

Author: S. Görög
Publisher: Elsevier
ISBN: 0444597522
Size: 71.10 MB
Format: PDF, Docs
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Studies in Analytical Chemistry, Volume 5: Quantitative Analysis of Steroids covers the pharmaceutical aspects of the analysis of steroid hormones. This book is divided into nine chapters that examine the biological-clinical analysis of other important groups of steroids, including sterols, vitamin D, bile acids, cardiac glycosides, and sapogenins. The material in the book is classified according to the main groups of steroids, individual chapters being devoted to sex hormones, corticosteroids, sterols, vitamins D, bile acids, cardiac glycosides, sapogenins, and miscellaneous steroids. The structure of each chapter is the same. In section 1 the fundamentals of the chemistry of the group of steroids in question are outlined. Section 2 provides a detailed description of the use of various spectroscopic, chromatographic, protein-binding and other methods, while Section 3 deals with the main problems encountered in the analysis of the group of steroids in question and with their solution using the methods described in Section 2. This book will prove useful to steroid and analytical chemists.

Handbook Of Chemical And Biological Plant Analytical Methods 3 Volume Set

Author: Shilin Chen
Publisher: John Wiley & Sons
ISBN: 1118874986
Size: 12.54 MB
Format: PDF, ePub, Docs
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Plants and plant-derived compounds and drugs are becoming moreand more popular with increasing numbers of scientists researchingplant analysis. The quality control of herbal drugs is alsobecoming essential to avoid severe health problems, and in thefuture many more new drugs will be developed from plantsources. This three-volume Handbook, featuring 47 detailed review articles,is unique as it deals with chemical and biological methodologiesfor plant analysis. It presents the most important and mostaccurate methods which are available for plant analysis. This comprehensive work is divided into six sections asfollows: Sample preparation and identification – discussingplant selection and collection, followed by extraction and samplepreparation methodologies. Extraction and sample preparation methodologies Instrumentation for chemical analysis - severalinstrumentations for chemical plant analysis are presented with anemphasis on hyphenated techniques, e.g. the coupling between HPLCand mass spectroscometry, and HPLC with NMR. Strategies for selective classes of compounds –coverage of the most interesting classes of compounds such aspolysaccharides, saponins, cardiotonic glycosides, alkaloids,terpenoids, lipids, volatile compounds and polyphenols (flavonoids, xanthones, coumarins, naphthoquinones, anthraquinones,proanthocyanidins, etc.). Biological Analysis - includes phenotyping, DNA barcodingtechniques, transcriptome analysis , microarray, metabolomics andproteomics. Drugs from Plants – covers the screening of plantextracts and strategies for the quick discovery of novelbioactive natural products. Safety assessment of herbal drugs ishighly dependent on outstanding chromatographic and spectroscopicmethods which are also featured here. This Handbook introduces to scientists involved in plant studiesthe current knowledge of methodologies in various fields ofchemically- and biochemically-related topics in plantresearch. The content from this Handbook will publish online within theEncyclopedia of Analytical Chemistry via Wiley Online Library: ahref="" Benefit from the introductory offer, valid until 30 November2014! Introductory price: £425.00 / $695.00 /€550.00 List price thereafter: £495.00 / $795.00 / €640.00

The Biology Of Cholesterol And Related Steroids

Author: N. B. Myant
Publisher: Butterworth-Heinemann
ISBN: 148328123X
Size: 34.24 MB
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The Biology of Cholesterol and Related Steroids focuses on the study of sterols in relation to living organisms. The publication first takes a look at the analysis of sterols and related steroids and the distribution of sterols and related steroids in nature, as well as the processes of extraction and separation and presence of sterols in plants, fungi, vertebrates, and invertebrates. The text then ponders on biosynthesis of sterols and metabolism of cholesterol. Topics include formation of fatty acid esters of cholesterol, steroid hormones, biosynthetic pathway to sterols, reaction mechanisms, and comparative aspects of sterol synthesis. The manuscript examines the developmental aspects of cholesterol metabolism and sterols in biological membranes. The book also reviews cholesterol synthesis in animal tissues, sterol metabolism in isolated cells, and epidemiology of the plasma cholesterol. Discussions focus on selection of statistical populations, genetic influences, regulation of sterol synthesis, general aspects of sterol metabolism, and removal of cell cholesterol in vivo. The publication is a dependable source of data for biochemists and readers interested in the biology of cholesterol and steroids.

High Performance Liquid Chromatography In Phytochemical Analysis

Author: Monika Waksmundzka-Hajnos
Publisher: CRC Press
ISBN: 9781420092615
Size: 73.61 MB
Format: PDF, Mobi
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The powerful, efficient technique of high performance liquid chromatography (HPLC) is essential to the standardization of plant-based drugs, identification of plant material, and creation of new herbal medicines. Filling the void in this critical area, High Performance Liquid Chromatography in Phytochemical Analysis is the first book to give a complete description of the techniques, materials, and instrumentation of column HPLC and its application to essentially all primary and secondary plant metabolites. Hailing from around the world and with vast expertise in HPLC phytochemical analysis, the contributors present a global, authoritative view of the field. The book looks at the role of HPLC in the analysis of herbal drugs, quality control of plant products in dietary supplements, and chemosystematics. It also covers the phytochemistry, pharmacology, and biological role of plant metabolites as well as various modes and techniques of HPLC analysis. The book then focuses on HPLC separation, identification, and quantification of particular classes of compounds in a variety of sample types, including plants, plant extracts, and plant-derived products. Along with its companion volume Thin Layer Chromatography in Phytochemistry, this comprehensive book presents the most important analytical approaches used in phytochemical analysis. It will help in solving problems connected with practical separations and the analyses of plant extract fractions of active metabolites.