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Atlas Of The Prenatal Mouse Brain

Author: Uta B. Schambra
Publisher: Academic Press
ISBN: 1483289087
Size: 16.52 MB
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The Atlas of the Prenatal Mouse Brain is the latest addition to Academic Press' list of atlases for neuroscientists and neuroscience students. It fills an urgent need for a comprehensive atlas of the developing mouse brain for use in studies of both normal and abnormal development. High-quality photomicrographs of brain sections are depicted in sagittal, coronal, and horizontal planes for four gestational age groups. Each photomicrograph is accompanied by a fully labeled, precision-drawn diagram for easy identification of brain structures. Researchers and students using normal, transgenic, or mutant mouse preparations in developmental neurobiology, neurotoxicology, and biotechnology will welcome this meticulously assembled and accessible guide. Presents 153 photomicrographs of serial brain sections Represents four gestational ages (GD 12 and 14 embryos; GD 16 and 18 fetuses), each depicted in sigittal, coronal, and horizontal planes Includes fully labeled diagrams identifying brain structures for each photomicrograph Provides complete alphabetical lists of brain structures and abbreviations Presents a full description of tissue preparation method Large format, 8-1/2 x 11" pages in a sturdy hardcover case

Prenatal Mouse Brain Atlas

Author: Uta Schambra
Publisher: Springer Science & Business Media
ISBN: 9780387470931
Size: 35.75 MB
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This is the only book available for studies of the mouse brain before birth. It presents a complete mapping of the developing mouse brain that features imaging of whole brain sections. Users will be able to compare structure shown in the Atlas to what they see in the microscope. This new, greatly expanded edition provides an easily accessible tool for researchers in the fields of normal and abnormal brain development.

Chemoarchitectonic Atlas Of The Developing Mouse Brain

Author: David M. Jacobowitz
Publisher: CRC Press
ISBN: 9780849326677
Size: 37.45 MB
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Representing the state-of-the-art in neurochemical mapping, Chemoarchitectonic Atlas of the Developing Mouse Brain provides a complete, full-color look at the developing mouse brain. Hundreds of coronal sections are presented, clearly illustrating structures at progressive stages of brain development.

Stereotaxic Neurosurgery In Laboratory Rodent

Author: Barbara Ferry
Publisher: Springer Science & Business
ISBN: 2817804724
Size: 65.59 MB
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Stereotaxic neurosurgery in rodents is used by a variety of people working at research laboratories (research staff, technicians, students at animal facilities...). The present handbook presents all the steps necessary to complete a stereotaxic neurosurgery protocol in accordance with current animal welfare guidelines. This book will guide surgeons step by step, from anesthesia to the post-surgery recovery procedures, including asepsis of the surgical tools and surgical zone, analgesia, correctly identifying the reference points on the skull and brain targets, etc. In keeping with the current international trends, the authors above all focus on the following points: the consideration of pain and how to best treat it depending on the type of surgery; and ensuring asepsis. This book will serve as an important reference work and valuable guidebook for the scientific community.

Guide To Techniques In Mouse Development Part A

Publisher: Academic Press
ISBN: 9780080887784
Size: 34.19 MB
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This volume comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. This volume is an update of volume 225 of MIE, "Guide to Techniques in Mouse Development", edited by P.M. Wassarman and M.L. DePamphilis and published in 1993. During the past 17 years many new technologies or methodologies have appeared for the study of mouse development and this volume comprehensively covers these, including: new techniques for the cryopreservation of gametes and embryos, production of transgenic and null (knockout) animals (use of ES cells), generation of conditional/inducible mutant animals, use of gene-trap mutagenesis, analysis of allele-specific expresion, use of new reporter constructs, humanizing of transgenic animals, transcript profiling of mouse development, imaging of mouse development, rederivation of animals and use of mouse genomics.

Building Brains

Author: David J. Price
Publisher: John Wiley & Sons
ISBN: 1119957664
Size: 57.14 MB
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The development of a brain from its simple beginnings in the embryo to the extraordinarily complex fully-functional adult structure is a truly remarkable process. Understanding how it occurs remains a formidable challenge despite enormous advances over the last century and current intense world-wide scientific research. A greater knowledge of how nervous systems construct themselves will bring huge benefits for human health and future technologies. Unravelling the mechanisms that lead to the development of healthy brains should help scientists tackle currently incurable diseases of the nervous system such as autism, epilepsy and schizophrenia (to name but a few), discover more about the processes that cause the uncontrolled growth associated with cancer and develop possible treatments. Building Brains provides a highly visual and readily accessible introduction to the main events that occur during neural development and the mechanisms by which they occur. Aimed at undergraduate students and postgraduates new to the field, who may not have a background in neuroscience and/or molecular genetics, it explains how cells in the early embryo first become neural, how their proliferation is controlled, what regulates the types of neural cells they become, how neurons connect to each other, how these connections are later refined under the influence of neural activity including that arising from experience, and why some neurons normally die. Key Features: A concise illustrated guide focusing on the core elements of current understanding of neural development, emphasising common principles underlying developmental mechanisms and supplemented by suggestions for further reading. Text boxes throughout provide further detail on selected major advances, issues of particular uncertainty or controversy and examples of human diseases that result from abnormal development. A balanced mammalian/non-mammalian perspective, drawing on examples from model organisms including the fruit fly, nematode worm, frog, zebrafish, chick, mouse, ferret, cat, monkey and human, and emphasising mechanisms that are conserved across species. Introduces the methods for studying neural development including genetics, transgenic technologies, advanced microscopy and computational modeling, allowing the reader to understand the main evidence underlying research advances. Student-friendly, full colour artwork reinforces important concepts; an extensive glossary and definitions in page margins help readers from different backgrounds; chapter summaries stress important points and aid revision. Associated Website includes a complete set of figures from the textbook.

Histology Atlas Of The Developing Prenatal And Postnatal Mouse Central Nervous System With Emphasis On Prenatal Days E7 5 To E18 5

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Evaluation of the central nervous system (CNS) in the developing mouse presents unique challenges, given the complexity of ontogenesis, marked structural reorganization over very short distances in 3 dimensions each hour, and numerous developmental events susceptible to genetic and environmental influences. Developmental defects affecting the brain and spinal cord arise frequently both in utero and perinatally as spontaneous events, following teratogen exposure, and as sequelae to induced mutations and thus are a common factor in embryonic and perinatal lethality in many mouse models. Knowledge of normal organ and cellular architecture and differentiation throughout the mouse’s life span is crucial to identify and characterize neurodevelopmental lesions. By providing a well-illustrated overview summarizing major events of normal in utero and perinatal mouse CNS development with examples of common developmental abnormalities, this annotated, color atlas can be used to identify normal structure and histology when phenotyping genetically engineered mice and will enhance efforts to describe and interpret brain and spinal cord malformations as causes of mouse embryonic and perinatal lethal phenotypes. The schematics and images in this atlas illustrate major developmental events during gestation from embryonic day (E)7.5 to E18.5 and after birth from postnatal day (P)1 to P21.

Normentafeln Zur Entwicklungsgeschichte Der Wirbelthiere

Author: Franz Keibel
ISBN: 9783743322875
Size: 58.79 MB
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Normentafeln zur Entwicklungsgeschichte der Wirbelthiere - Band 4 ist ein unveranderter, hochwertiger Nachdruck der Originalausgabe aus dem Jahr 1897. Hansebooks ist Herausgeber von Literatur zu unterschiedlichen Themengebieten wie Forschung und Wissenschaft, Reisen und Expeditionen, Kochen und Ernahrung, Medizin und weiteren Genres.Der Schwerpunkt des Verlages liegt auf dem Erhalt historischer Literatur.Viele Werke historischer Schriftsteller und Wissenschaftler sind heute nur noch als Antiquitaten erhaltlich. Hansebooks verlegt diese Bucher neu und tragt damit zum Erhalt selten gewordener Literatur und historischem Wissen auch fur die Zukunft bei."

Atlas Of The Developing Rat Nervous System

Author: George Paxinos
Publisher: Academic Press
ISBN: 1483284913
Size: 52.63 MB
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In response to the explosion of research in developmental neurobiology, this new edition of the Atlas of the Developing Rat Brain has been expanded to include all of the plates and diagrams of the previous book, PLUS an additional 95 plates and 95 diagrams delineating the entire rat nervous system. Atlas of the Developing Rat Nervous System features large, high-magnification photographs of serial brain sections of the embryonic and neonatal laboratory rat, with opposing fully labeled diagrams. Complementing the classic atlas by Paxinos and Watson, The Rat Brain in Stereotaxic Coordinates, Second Edition (Academic Press, 1986), this new atlas is the standard reference for developmental neuroscientists. Key Features * Provides section-by-section photographs and accompanying labeled diagrams of the embryonic and neonatal rat brain * Shows brain development at Embryonic Days 14 (Whole embryo), 16, 17, and 19, as well as Postnatal Day 0 * Delineates nerves, ganglia, arteries, veins, bones, and foramina of the head on Embryonic Days 14 and 19 * Depicts 912 brain structures or their primordial counterparts * Large size in an easy-to-use, spiral-bound format * Includes a full list of abbreviations, index of structures, and references * 224 photographs alongside meticulously drawn diagrams depict the central and peripheral nervous system and other body organs * Depicts ages E14, E16, and E19 in the customary coronal and sagittal planes and E17 and P0 in the coronal plane