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Basic And Clinical Biostatistics

Author: Beth Dawson
Publisher:
ISBN: 9780838505106
Size: 42.62 MB
Format: PDF, Docs
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Here is absolutely everything medical students need to know about biostatistics and quantitative methods as applied to medicine, clinical practice, and research. Case study approach introduces problems at the beginning of each chapter, to clarify concepts. Includes CD-ROM of data sets.

Basic Clinical Biostatistics Fourth Edition

Author: Beth Dawson
Publisher: McGraw Hill Professional
ISBN: 0071781323
Size: 29.43 MB
Format: PDF, ePub
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The ideal way to develop sound judgment about data applicable to clinical care First choice of students, educators, and practitioners A thorough, meaningful, and interesting presentation of biostatistics Helps students become informed users and consumers of biostatistics Learn to evaluate and apply statistics in medicine, medical research, and all health-related fields. Emphasis on the basics of biostatistics and epidemiology and the clinical applications in evidence-based medicine and decision-making methods NEW chapter on survey research Expanded discussion of logistic regression, the Cox model, and other multivariate statistical methods Key Concepts in each chapter pinpoint essential information Presenting Problems drawn from studies in the medical literature that illustrate the various statistical methods Downloadable NCSS statistical software, procedures, and data sets from the presenting problems End-of-chapter exercises Multiple-choice final practice exam

Basic Clinical Biostatistics Fourth Edition

Author: Beth Dawson
Publisher: McGraw-Hill Professional
ISBN: 9780071410175
Size: 68.15 MB
Format: PDF, Mobi
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A Doody's Core Title for 2011! A comprehensive user-friendly introduction to biostatistics and epidemiology applied to medicine, clinical practice, and research. Features “Presenting Problems” (case studies) drawn from studies published in the medical literature, end-of-chapter, and a CD-ROM with data sets and statistical software programs.

Medical Epidemiology

Author: Raymond S. Greenberg
Publisher: McGraw-Hill Professional
ISBN: 9780071416375
Size: 66.72 MB
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Recognized for its succinct and compelling discussion of epidemiology and its role in medicine. 4 STAR DOODY'S REVIEW! "This is a well-written, easy to read, well-illustrated primer, which medical students and others should read. A nice feature of the book is all key concepts are highlighted for emphasis, with summaries at the beginning and end of each chapter."--Doody's Review Service This book provides students with an overview of the principles and concepts of epidemiology and illustrates the complementary relationship between population-based science and the care of patients Thoroughly updated, this new edition features epidemiologic implications of bio-terrorism, “Patient Profiles” within each chapter, and USMLE clinical vignettes within the “Study Question” section of each chapter.

Understanding Clinical Research

Author: Renato D. Lopes
Publisher: McGraw Hill Professional
ISBN: 0071792651
Size: 12.88 MB
Format: PDF, Mobi
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A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials

Writing Clinical Research Protocols

Author: Evan DeRenzo
Publisher: Elsevier
ISBN: 9780080454207
Size: 10.20 MB
Format: PDF, Kindle
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This highly engaging guide for clinical researchers provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. Writing Clinical Research Protocols includes practical information on ethical principles in clinical research, designing appropriate research studies, writing consent and assent documents, getting protocols approved, special populations, confidentiality issues, and the reporting of adverse events. A valuable appendix includes a listing of web resources about research ethics as well as a glossary. This is an invaluable resource for basic scientists collaborating in clinical trials, physician investigators, clinical research fellows, research nurse coordinators, residents, and anyone who wants a better understanding of the clinical trials process. Walks investigators and trainees through identification of the ethical aspects of each section of a clinical research protocol Includes a chapter containing Case Histories Contains information on conducting clinical research within the pharmaceutical industry An appendix includes internet resources and world wide web addresses for important research ethics documents and regulations Chapter on 'Study Design and Methodology' purposely expanded to explicitly address biostatistical considerations

Clinical And Translational Science

Author: David Robertson
Publisher: Academic Press
ISBN: 012802111X
Size: 15.90 MB
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Clinical and Translational Science: Principles of Human Research, Second Edition, is the most authoritative and timely resource for the broad range of investigators taking on the challenge of clinical and translational science, a field that is devoted to investigating human health and disease, interventions, and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. This updated second edition has been prepared with an international perspective, beginning with fundamental principles, experimental design, epidemiology, traditional and new biostatistical approaches, and investigative tools. It presents complete instruction and guidance from fundamental principles, approaches, and infrastructure, especially for human genetics and genomics, human pharmacology, research in special populations, the societal context of human research, and the future of human research. The book moves on to discuss legal, social, and ethical issues, and concludes with a discussion of future prospects, providing readers with a comprehensive view of this rapidly developing area of science. Introduces novel physiological and therapeutic strategies for engaging the fastest growing scientific field in both the private sector and academic medicine Brings insights from international leaders into the discipline of clinical and translational science Addresses drug discovery, drug repurposing and development, innovative and improved approaches to go/no-go decisions in drug development, and traditional and innovative clinical trial designs

Fundamentals Of Clinical Trials

Author: Lawrence M. Friedman
Publisher: Springer
ISBN: 331918539X
Size: 11.38 MB
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This is the fifth edition of a very successful textbook on clinical trials methodology, written by recognized leaders who have long and extensive experience in all areas of clinical trials. The three authors of the first four editions have been joined by two others who add great expertise. A chapter on regulatory issues has been included and the chapter on data monitoring has been split into two and expanded. Many contemporary clinical trial examples have been added. There is much new material on adverse events, adherence, issues in analysis, electronic data, data sharing and international trials. This book is intended for the clinical researcher who is interested in designing a clinical trial and developing a protocol. It is also of value to researchers and practitioners who must critically evaluate the literature of published clinical trials and assess the merits of each trial and the implications for the care and treatment of patients. The authors use numerous examples of published clinical trials to illustrate the fundamentals. The text is organized sequentially from defining the question to trial closeout. One chapter is devoted to each of the critical areas to aid the clinical trial researcher. These areas include pre-specifying the scientific questions to be tested and appropriate outcome measures, determining the organizational structure, estimating an adequate sample size, specifying the randomization procedure, implementing the intervention and visit schedules for participant evaluation, establishing an interim data and safety monitoring plan, detailing the final analysis plan and reporting the trial results according to the pre-specified objectives. Although a basic introductory statistics course is helpful in maximizing the benefit of this book, a researcher or practitioner with limited statistical background would still find most if not all the chapters understandable and helpful. While the technical material has been kept to a minimum, the statistician may still find the principles and fundamentals presented in this text useful.