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Introduction To Genomics

Author: Arthur Lesk
Publisher: Oxford University Press
ISBN: 0198754833
Size: 45.41 MB
Format: PDF
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Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on andoff in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time. Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes. The bookcovers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. The Online Resource Centre accompanying Introduction to Genomics features: For students: * Extensive and imaginative weblems (web-based problems) for each chapter designed to give you practice with the tools required for further study and research in the field* Hints and answers to end-of-chapter problems and exercises support your self-directed learning* Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research * Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primary literature* Rotating figures allow you to visualize complex structuresFor registered adopters: * Downloadable figures from the book.

Why I Am Not A Scientist

Author: Jonathan Marks
Publisher: Univ of California Press
ISBN: 0520259602
Size: 45.43 MB
Format: PDF, Mobi
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"Highly readable and informative, this critical series of vignettes illustrates a long history of the corruption of science by folk beliefs, careerism, and sociopolitical agendas. Marks repeatedly brings home the message that we should challenge scientists, especially molecular geneticists, before we accept their results and give millions of dollars in public and private funds toward their enterprises."—Russell Tuttle, The University of Chicago “Jonathan Marks has produced a personal and compelling story of how science works. His involvement in scientific endeavor in human biology and evolution over the past three decades and his keen sense of the workings of science make this book a must read for both scientists and lay readers. In this sense, the lay reader will learn how scientists should and shouldn't think and some scientists who read this book will come away thinking they are truly not scientists nor would they want to be.”—Rob DeSalle, American Museum of Natural History “Jonathan Marks's Why I Am Not a Scientist provides food for thought, and as expected, it's digestible. In unusually broad perspective, this anthropology of knowledge considers science and race and racism, gender, fraud, misconduct and creationism in a way that makes one proud to be called a scientist.”—George J. Armelagos, Emory University

Bio2010

Author: Committee on Undergraduate Biology Education to Prepare Research Scientists for the 21st Century
Publisher: National Academies Press
ISBN: 0309085357
Size: 72.12 MB
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Biological sciences have been revolutionized, not only in the way research is conducted -- with the introduction of techniques such as recombinant DNA and digital technology -- but also in how research findings are communicated among professionals and to the public. Yet, the undergraduate programs that train biology researchers remain much the same as they were before these fundamental changes came on the scene. This new volume provides a blueprint for bringing undergraduate biology education up to the speed of today's research fast track. It includes recommendations for teaching the next generation of life science investigators, through: Building a strong interdisciplinary curriculum that includes physical science, information technology, and mathematics. Eliminating the administrative and financial barriers to cross-departmental collaboration. Evaluating the impact of medical college admissions testing on undergraduate biology education. Creating early opportunities for independent research. Designing meaningful laboratory experiences into the curriculum. The committee presents a dozen brief case studies of exemplary programs at leading institutions and lists many resources for biology educators. This volume will be important to biology faculty, administrators, practitioners, professional societies, research and education funders, and the biotechnology industry.

Statistics For Terrified Biologists

Author: Helmut van Emden
Publisher: John Wiley & Sons
ISBN: 1118541677
Size: 60.47 MB
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“We highly recommend it—not just for statistically terrified biology students and faculty, but also for those who are occasionally anxious or uncertain. In addition to being a good starting point to learn statistics, it is a useful place to return to refresh your memory.” –The Quarterly Review of Biology, March 2009 "During the entire course of my Ph.D. I've been (embarrasingly) looking for a way to teach myself the fundamentals of statistical analysis. At this point in my education, I've come to realize that often times, simply knowing the basics is enough for you to properly apply even the most complex analytical methods. ‘Statistics for Terrified Biologists’ has been just such a book - it was more than worth the $40 I spent on it, and while my 'book clubs' aren't meant to be reviews, I highly recommend the book to anyone who's in a similar predicament to my own." –Carlo Artieri's Blog Book Club The typical biology student is “hardwired” to be wary of any tasks involving the application of mathematics and statistical analyses, but the plain fact is much of biology requires interpretation of experimental data through the use of statistical methods. This unique textbook aims to demystify statistical formulae for the average biology student. Written in a lively and engaging style, Statistics for Terrified Biologists draws on the author’s 30 years of lecturing experience. One of the foremost entomologists of his generation, van Emden has an extensive track record for successfully teaching statistical methods to even the most guarded of biology students. For the first time basic methods are presented using straightforward, jargon-free language. Students are taught to use simple formulae accurately to interpret what is being measured with each test and statistic, while at the same time learning to recognize overall patterns and guiding principles. Complemented by simple illustrations and useful case studies, this is an ideal statistics resource tool for undergraduate biology and environmental science students who lack confidence in their mathematical abilities.

Biology For Engineers

Author: Arthur T. Johnson
Publisher: CRC Press
ISBN: 1439894027
Size: 17.64 MB
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Biology is a critical application area for engineering analysis and design, and students in engineering programs must be well-versed in the fundamentals of biology as they relate to their field. Biology for Engineers is an introductory text that minimizes unnecessary memorization of connections and classifications and instead emphasizes concepts, technology, and the utilization of living things. Whether students are headed toward a bio-related engineering degree or one of the more traditional majors, biology is so important that all engineering students should know how living things work and act. Classroom-tested at the University of Maryland, this comprehensive text introduces concepts and terminology needed to understand more advanced biology literature. Filled with practical detailed examples, the book presents: Scientific principles relevant to biology that all engineers must know A discussion of biological responses from the perspective of a broad range of fields such as psychology, human factors, genetics, plant and animal physiology, imaging, control systems, actuary, and medicine A thorough examination of the scaling of biological responses and attributes A classification of different types of applications related to biological systems Tables of useful information that are nearly impossible to find elsewhere A series of questions at the end of each chapter to test comprehension Emphasizing the ever-present interactions between a biological unit and its physical, chemical, and biological environments, the book provides ample instruction on the basics of physics, chemistry, mathematics, and engineering. It brings together all of the concepts one needs to understand the role of biology in modern technology.

The Scientist S Guide To Writing

Author: Stephen B. Heard
Publisher: Princeton University Press
ISBN: 1400881145
Size: 78.89 MB
Format: PDF, Kindle
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The ability to write clearly is critical to any scientific career. The Scientist's Guide to Writing provides practical advice to help scientists become more effective writers so that their ideas have the greatest possible impact. Drawing on his own experience as a scientist, graduate adviser, and editor, Stephen Heard emphasizes that the goal of all scientific writing should be absolute clarity; that good writing takes deliberate practice; and that what many scientists need are not long lists of prescriptive rules but rather direct engagement with their behaviors and attitudes when they write. He combines advice on such topics as how to generate and maintain writing momentum with practical tips on structuring a scientific paper, revising a first draft, handling citations, responding to peer reviews, managing coauthorships, and more. In an accessible, informal tone, The Scientist's Guide to Writing explains essential techniques that students, postdoctoral researchers, and early-career scientists need to write more clearly, efficiently, and easily. Emphasizes writing as a process, not just a product Encourages habits that improve motivation and productivity Explains the structure of the scientific paper and the function of each part Provides detailed guidance on submission, review, revision, and publication Addresses issues related to coauthorship, English as a second language, and more

Time Love Memory

Author: Jonathan Weiner
Publisher: Vintage
ISBN: 0804153361
Size: 50.96 MB
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How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives. Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.

Learning About Your Genes A Primer For Non Biologists

Author: Friedberg Errol C
Publisher: World Scientific
ISBN: 9813272635
Size: 55.62 MB
Format: PDF
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Genes were unknowingly discovered in the 19th century by Gregor Mendel, a Czechoslovakian monk. It was later established that genes are made of DNA, a biological compound found in tiny thread-like structures called chromosomes that are located in the nuclei of all cells in our bodies. DNA consists of chains of entities called bases of which there are four in nature. DNA consists of long chains of bases (sometimes referred to as DNA sequences) that are joined in any order, but the precise order and length of which constitute different genes.Many (but not all) genes carry a code called the genetic code, a code that instructs the synthesis (manufacture) of the many hundreds of proteins that we require to survive and execute the many functions of life. The genetic code was deciphered in relatively recent years and is considered one of the most significant discoveries in the history of biology.Genes that encode instructions for the synthesis of proteins and those that regulate the manufacture of proteins comprise a mere two percent of our DNA. Despite our extensive knowledge of biology and the sub-discipline of molecular biology (the study of biology at the molecular level), the function (if any) of the rest of the DNA in our cells is unknown.Research about genes and DNA has in recent years spawned an endeavor referred to as the Human Genome Project, an international collaboration that has successfully determined, stored, and rendered publicly available the sequences of almost all the genetic content of the chromosomes of the human organism, otherwise known as the human genome.DNA sequences that are unique to every person on earth have been discovered (DNA fingherprints) and are now used for identifying criminals. The book relates a specific example of identifying a criminal who murdered two women.This is the first and only book that we are aware of that educates non-biologists about genes. It is written in a style and uses a vocabulary that can be comprehended by the average reader who knows very little if anything about genes.

A New Biology For The 21st Century

Author: National Research Council
Publisher: National Academies Press
ISBN: 9780309147866
Size: 42.12 MB
Format: PDF, Kindle
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Now more than ever, biology has the potential to contribute practical solutions to many of the major challenges confronting the United States and the world. A New Biology for the 21st Century recommends that a "New Biology" approach--one that depends on greater integration within biology, and closer collaboration with physical, computational, and earth scientists, mathematicians and engineers--be used to find solutions to four key societal needs: sustainable food production, ecosystem restoration, optimized biofuel production, and improvement in human health. The approach calls for a coordinated effort to leverage resources across the federal, private, and academic sectors to help meet challenges and improve the return on life science research in general.

A Computer Scientist S Guide To Cell Biology

Author: William W. Cohen
Publisher: Springer Science & Business Media
ISBN: 0387482784
Size: 72.31 MB
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This book is designed specifically as a guide for Computer Scientists needing an introduction to Cell Biology. The text explores three different facets of biology: biological systems, experimental methods, and language and nomenclature. The author discusses what biologists are trying to determine from their experiments, how various experimental procedures are used and how they relate to accepted concepts in computer science, and the vocabulary necessary to read and understand current literature in biology. The book is an invaluable reference tool and an excellent starting point for a more comprehensive examination of cell biology.