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Biomaterials For Clinical Applications

Author: Sujata K. Bhatia
Publisher: Springer Science & Business Media
ISBN: 9781441969200
Size: 38.24 MB
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Biomaterials for Clinical Applications is organized according to the World Health Organization’s report of the top 11 causes of death worldwide, and lays out opportunities for both biomaterials scientists and physicians to tackle each of these leading contributors to mortality. The introductory chapter discusses the global burden of disease. Each of the subsequent eleven chapters focuses on a specific disease process, beginning with the leading cause of death worldwide, cardiovascular disease. The chapters start with describing diseases where clinical needs are most pressing, and then envisions how biomaterials can be designed to address these needs, instead of the more technologically centered approached favored by most books in the field. This book, then, should appeal to chemical engineers and bioengineers who are designing new biomaterials for drug delivery and vaccine delivery, as well as tissue engineering.

Hemocompatibility Of Biomaterials For Clinical Applications

Author: Christopher Siedlecki
Publisher: Woodhead Publishing
ISBN: 0081004990
Size: 19.27 MB
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Hemocompatibility of Biomaterials for Clinical Applications: Blood-Biomaterials Interactions summarizes the state-of-the-art on this important subject. The first part of the book reviews the latest research on blood composition and response, mechanisms of coagulation, test standards and methods. Next, the book assesses techniques for modifying biomaterial surfaces and developing coatings to improve hemocompatibility. In the final sections, users will find discussions on ways to improve the hemocompatibility of particular classes of biomaterials and a review of methods for improving medical devices. Provides comprehensive information on the fundamentals of hemocompatibility and new technologies Combines research in the biomaterials field in a digestible format for clinical applications Provides a complete overview biomaterials in current use and test methods

Clinical Applications Of Biomaterials

Author: Gurbinder Kaur
Publisher: Springer
ISBN: 331956059X
Size: 42.16 MB
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This book examines the most novel and state-of-the-art applications of biomaterials, with chapters that exemplify approaches with targeted drug delivery, diabetes, neurodegenerative diseases and cranioplasty implants. Expert contributors analyze biomaterials such as calcium phosphate, sol-gel and quenched glasses, metallic and polymer implants, bioactive glass, and polymer composites while also covering important areas such as the soft tissue replacement, apatites, bone regeneration and cell encapsulation. This book is appropriate for biomedical engineers, materials scientists, and clinicians who are seeking to implement the most advanced approaches and technologies with their patients.

Translating Biomaterials For Bone Graft

Author: Joo L. Ong
Publisher: CRC Press
ISBN: 1315363518
Size: 14.98 MB
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Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

Engineering Biomaterials For Regenerative Medicine

Author: Sujata K. Bhatia
Publisher: Springer Science & Business Media
ISBN: 9781461410805
Size: 17.65 MB
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Regeneration of tissues and organs remains one of the great challenges of clinical medicine, and physicians are constantly seeking better methods for tissue repair and replacement. Tissue engineering and regenerative medicine have been investigated for virtually every organ system in the human body, and progress is made possible by advances in materials science, polymer chemistry, and molecular biology. This book reviews the current status of biomaterials for regenerative medicine, and highlights advances in both basic science and clinical practice. The latest methods for regulating the biological and chemical composition of biomaterials are described, together with techniques for modulating mechanical properties of engineered constructs. Contributors delineate methods for guiding the host response to implantable materials, and explain the use of biologically-inspired materials for optimal biological functionality and compatibility. The book culminates in a discussion of the clinical applications of regenerative medicine. By integrating engineering and clinical medicine, Engineering Biomaterials for Regenerative Medicine examines how tissue engineering and regenerative medicine can be translated into successful therapies to bridge the gap between laboratory and clinic. The book will aid materials scientists and engineers in identifying research priorities to fulfill clinical needs, and will also enable physicians to understand novel biomaterials that are emerging in the clinic. This integrated approach also gives engineering students a sense of the excitement and relevance of materials science in the development of novel therapeutic strategies.

Bioceramics And Their Clinical Applications

Author: T Kokubo
Publisher: Elsevier
ISBN: 1845694228
Size: 65.26 MB
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Bioceramics have been used very successfully within the human body for many years. They are commonly used in orthopaedic surgery and dentistry but they are potentially suitable for a wide range of important applications within the medical device industry. This important book reviews the range of bioceramics, their properties and range of clinical uses. Chapters in the first section of the book discusses issues of significance to a range of bioceramics such as their structure, mechanical properties and biological interactions. The second part reviews the fabrication, microstructure and properties of specific bioceramics and glasses, concentrating on the most promising materials. These include alumina and zirconia ceramics, bioactive glasses and bioactive glass-ceramics, calcium sulphate, tricalcium phosphate-based ceramics, hydroxyapatite, tricalcium phosphate/hydroxyapatite biphasic ceramics, si-substrated hydroxyapatite, calcium phosphate cement, calcium phosphate coating, titania-based materials, ceramic-polymer composites, dental ceramics and dental glass-ceramics. The final group of chapters reviews the clinical applications of bioceramics in joint replacement, bone grafts, tissue engineering and dentistry. Bioceramics and their clinical applications is written by leading academics from around the world and it provides an authoritative review of this highly active area of research. This book is a useful resource for biomaterials scientists and engineers, as well as for clinicians and the academic community. Provides an authoritative review of this highly active area of research Discusses issues of significance of a range of bioceramics such as their structure, mechanical properties and biological interactions Reviews the clinical applications of bioceramics in joint replacement, bone grafts, tissue engineering and dentistry

Bone Grafts And Bone Substitutes

Author: Aziz Nather
Publisher: World Scientific
ISBN: 9814481475
Size: 69.11 MB
Format: PDF
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This book provides the latest updates on the major challenges of bridging large bone defects, where options range from autografts, “tissue engineered bone”, biomaterials (hydroxyapatite, polycaprolactone and third generation biomaterials) to prostheses. Emphasis has been made on bone tissue engineering, the current state-of-the-art in this field, problems encountered with cell culture technology, scaffolds and bone growth factors (including genomics) and the use of gene therapy for the application of bone growth factors. Attention has also been given to the use of bone autografts. It also covers the use of biomaterials and prostheses as other options for reconstruction. Clinical applications, in addition to the basic science, are also included throughout the discussions. Contents:Basic Science of BoneAutograftsAllograftsGenomicsBone Tissue EngineeringGrowth FactorsCeramicsProstheses Readership: Undergraduate students, graduate students, researchers and lecturers in bone tissue engineering, bone growth factors, biomaterials, autografts, allografts, prostheses, as well as orthopaedic surgeons, plastic and reconstructive surgeons, maxillo-facial surgeons and tissue bank operators. Keywords:Bone Grafts;Bone Substitutes;Basic Science;Clinical Applications;Bone Tissue Engineering;Bone Growth Factor;Genomics;Bone Gene Therapy;BiomaterialsKey Features:Latest updates on the major challenges of bridging large bone defects, including state-of-the-art optionsClinical applications highlighted