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Bioprocess Engineering

Author: Michael L. Shuler
Publisher: Prentice Hall
ISBN: 0132901412
Size: 31.32 MB
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The Leading Introduction to Biochemical and Bioprocess Engineering, Updated with Key Advances in Productivity, Innovation, and Safety Bioprocess Engineering, Third Edition, is an extensive update of the world’s leading introductory textbook on biochemical and bioprocess engineering and reflects key advances in productivity, innovation, and safety. The authors review relevant fundamentals of biochemistry, microbiology, and molecular biology, including enzymes, cell functions and growth, major metabolic pathways, alteration of cellular information, and other key topics. They then introduce evolving biological tools for manipulating cell biology more effectively and to reduce costs of bioprocesses. This edition presents major advances in the production of biologicals; highly productive techniques for making heterologous proteins; new commercial applications for both animal and plant cell cultures; key improvements in recombinant DNA microbe engineering; techniques for more consistent authentic post-translational processing of proteins; and other advanced topics. It includes new, improved, or expanded coverage of The role of small RNAs as regulators Transcription, translation, regulation, and differences between prokaryotes and eukaryotes Cell-free processes, metabolic engineering, and protein engineering Biofuels and energy, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions Synthetic biology The growing role of genomics and epigenomics Population balances and the Gompetz equation for batch growth and product formation Microreactors for scale-up/scale-down, including rapid scale-up of vaccine production The development of single-use technology in bioprocesses Stem cell technology and utilization Use of microfabrication, nanobiotechnology, and 3D printing techniques Advances in animal and plant cell biotechnology The text makes extensive use of illustrations, examples, and problems, and contains references for further reading as well as a detailed appendix describing traditional bioprocesses. Register your product at informit.com/register for convenient access to downloads, updates, and corrections as they become available.

Bioprocess Engineering

Author: Michael L. Shuler
Publisher:
ISBN: 9780137062706
Size: 29.43 MB
Format: PDF, ePub
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The Leading Introduction to Biochemical and Bioprocess Engineering, Updated with Key Advances in Productivity, Innovation, and Safety Bioprocess Engineering, Third Edition, is an extensive update of the world's leading introductory textbook on biochemical and bioprocess engineering and reflects key advances in productivity, innovation, and safety. The authors review relevant fundamentals of biochemistry, microbiology, and molecular biology, including enzymes, cell functions and growth, major metabolic pathways, alteration of cellular information, and other key topics. They then introduce evolving biological tools for manipulating cell biology more effectively and to reduce costs of bioprocesses. This edition presents major advances in the production of biologicals; highly productive techniques for making heterologous proteins; new commercial applications for both animal and plant cell cultures; key improvements in recombinant DNA microbe engineering; techniques for more consistent authentic post-translational processing of proteins; and other advanced topics. It includes new, improved, or expanded coverage of The role of small RNAs as regulators Transcription, translation, regulation, and differences between prokaryotes and eukaryotes Cell-free processes, metabolic engineering, and protein engineering Biofuels and energy, including coordinated enzyme systems, mixed-inhibition and enzyme-activation kinetics, and two-phase enzymatic reactions Synthetic biology The growing role of genomics and epigenomics Population balances and the Gompetz equation for batch growth and product formation Microreactors for scale-up/scale-down, including rapid scale-up of vaccine production The development of single-use technology in bioprocesses Stem cell technology and utilization Use of microfabrication, nanobiotechnology, and 3D printing techniques Advances in animal and plant cell biotechnology The text makes extensive use of illustrations, examples, and problems, and contains references for further reading as well as a detailed appendix describing traditional bioprocesses.

Bioprocess Engineering

Author: Michael L. Shuler
Publisher: Pearson College Division
ISBN: 9780130819086
Size: 45.84 MB
Format: PDF, Kindle
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This concise yet comprehensive text introduces the essential concepts of bioprocessing - internal structure and functions of different types of microorganisms, major metabolic pathways, enzymes, microbial genetics, kinetics and stoichiometry of growth and product information - to traditional chemical engineers and those in related disciplines. It explores the engineering principles necessary for bioprocess synthesis and design, and illustrates the application of these principles to modern biotechnology for production of pharmaceuticals and biologics, solution of environmental problems, production of commodities, and medical applications.

Bioprocess Engineering

Author: Shijie Liu
Publisher: Elsevier
ISBN: 0444637931
Size: 55.54 MB
Format: PDF
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Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems. Includes the mechanistic description of biotransformations and chemical transformations Provides quantitative descriptions of bioprocesses Contains extensive illustrative drawings, which make the understanding of the subject easy Includes bioprocess kinetics and reactor analysis Contains examples of the various process parameters, their significance, and their specific practical use Incorporates sustainability concepts into the various bioprocesses

Bioprocess Engineering Principles

Author: Pauline M. Doran
Publisher: Academic Press
ISBN: 012220851X
Size: 44.57 MB
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This welcome new edition covers bioprocess engineering principles for the reader with a limited engineering background. It explains process analysis from an engineering point of view, using worked examples and problems that relate to biological systems. Application of engineering concepts is illustrated in areas of modern biotechnology such as recombinant protein production, bioremediation, biofuels, drug development, and tissue engineering, as well as microbial fermentation. The main sub-disciplines within the engineering curriculum are all covered; Material and Energy Balances, Transport Processes, Reactions and Reactor Engineering. With new and expanded material, Doran's textbook remains the book of choice for students seeking to move into bioprocess engineering. NEW TO THIS EDITION: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations New to this edition: All chapters thoroughly revised for current developments, with over 200 pgs of new material, including significant new content in: Metabolic Engineering Sustainable Bioprocessing Membrane Filtration Turbulence and Impeller Design Downstream Processing Oxygen Transfer Systems Over 150 new problems and worked examples More than 100 new illustrations

Biochemical Engineering Second Edition

Author: Douglas S. Clark
Publisher: CRC Press
ISBN: 9780824789497
Size: 66.85 MB
Format: PDF, Mobi
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This work provides comprehensive coverage of modern biochemical engineering, detailing the basic concepts underlying the behaviour of bioprocesses as well as advances in bioprocess and biochemical engineering science. It includes discussions of topics such as enzyme kinetics and biocatalysis, microbial growth and product formation, bioreactor design, transport in bioreactors, bioproduct recovery and bioprocess economics and design. A solutions manual is available to instructors only.

Fundamentals Of Modern Bioprocessing

Author: Sarfaraz K. Niazi
Publisher: CRC Press
ISBN: 1466585749
Size: 33.94 MB
Format: PDF
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Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.

Bioseparations Science And Engineering

Author: Roger G. Harrison
Publisher: Oxford University Press
ISBN: 0190213736
Size: 21.68 MB
Format: PDF, ePub
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Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer? is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.

Biochemical Engineering

Author: Shigeo Katoh
Publisher: John Wiley & Sons
ISBN: 3527685014
Size: 59.14 MB
Format: PDF, Mobi
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Completely revised, updated, and enlarged, this second edition now contains a subchapter on biorecognition assays, plus a chapter on bioprocess control added by the new co-author Jun-ichi Horiuchi, who is one of the leading experts in the field. The central theme of the textbook remains the application of chemical engineering principles to biological processes in general, demonstrating how a chemical engineer would address and solve problems. To create a logical and clear structure, the book is divided into three parts. The first deals with the basic concepts and principles of chemical engineering and can be read by those students with no prior knowledge of chemical engineering. The second part focuses on process aspects, such as heat and mass transfer, bioreactors, and separation methods. Finally, the third section describes practical aspects, including medical device production, downstream operations, and fermenter engineering. More than 40 exemplary solved exercises facilitate understanding of the complex engineering background, while self-study is supported by the inclusion of over 80 exercises at the end of each chapter, which are supplemented by the corresponding solutions. An excellent, comprehensive introduction to the principles of biochemical engineering.

Bioreaction Engineering Principles

Author: Jens Nielsen
Publisher: Springer
ISBN: 1461507677
Size: 71.66 MB
Format: PDF, Kindle
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This is the second edition of the text "Bioreaction Engineering Principles" by Jens Nielsen and John Villadsen, originally published in 1994 by Plenum Press (now part of Kluwer). Time runs fast in Biotechnology, and when Kluwer Plenum stopped reprinting the first edition and asked us to make a second, revised edition we happily accepted. A text on bioreactions written in the early 1990's will not reflect the enormous development of experimental as well as theoretical aspects of cellular reactions during the past decade. In the preface to the first edition we admitted to be newcomers in the field. One of us (JV) has had 10 more years of job training in biotechnology, and the younger author (IN) has now received international recognition for his work with the hottest topics of "modem" biotechnology. Furthermore we are happy to have induced Gunnar Liden, professor of chemical reaction engineering at our sister university in Lund, Sweden to join us as co-author of the second edition. His contribution, especially on the chemical engineering aspects of "real" bioreactors has been of the greatest value. Chapter 8 of the present edition is largely unchanged from the first edition. We wish to thank professor Martin Hjortso from LSU for his substantial help with this chapter.