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Current Topics In Bone Biology

Author: Hong-wen Deng
Publisher: World Scientific
ISBN: 981448072X
Size: 31.10 MB
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This book covers a wide spectrum of areas related to basic bone research. While bone remodeling, bone development, and osteoclast biology constitute the main contents, topics important to the understanding of bone metabolism and treatment of bone-related diseases are also intensively reviewed. Three chapters are dedicated to the classic topic of bone mechanics, which include a brief overview of the mechanostat hypothesis, a more detailed review on mechanotransduction and bone adaptation, and a chapter illustrating the basic principles of bone mechanical testing. New emerging fields such as skeletal stem cells, bone tissue engineering, phytoestrogens applications, and bone genetics study using mouse models, are also covered in detail. The book closes with a special chapter dedicated to state-of-the-art advances in bone biology research. Contents:International Chinese Hard Tissue Society — The Power that Connects the World of Science and Culture (D X Ji & W S S Jee)Integrated Bone Tissue Anatomy and Physiology (X-J Li & W S S Jee)Skeletal Stem Cells (M Connolly & G Li)Osteoclast Biology (X Feng & H Zhou)Intercellular Communication of Osteoblast and Osteoclast in Bone Diseases (J Xu et al.)Osteoclasts and Inflammatory Osteolysis (L Xing et al.)Endochrondral Bone Formation and Extracellular Matrix (Q Chen et al.)Bone Morphogenetic Proteins in Bone Formation and Development (X-J Qi et al.)Mechanical Testing for Bone Specimens (L Qin & M Zhang)Estrogens and Androgens on Bone Metabolism (A Kung & J Gu)Phytoestrogens and Bone Health: Mechanisms of Action (Z C Dang)Regulation of Bone Remodeling (D Chen et al.)TGFB in Chondrocyte Biology and Cartilage Pathology (T F Li et al.)Bone Health in Children and Adolescents (J M Lappe)The Mechanostat Hypothesis for Bones and Other Skeletal Organs (H M Frost)Mechanotransduction and Its Role in Bone Adaptation (Y Qin & C Rubin)Bio-Pathology of Bone Tumors (L Huang et al.)Bone Tissue Engineering (X Yang & R O C Oreffo)Bone Genetic Factors Determined Using Mouse Models (W Gu & Y Jiao)Recent Advances in Bone Biology Research (D Chen et al.) Readership: Scientists and researchers in the bone field; clinicians, especially endocrinologists, orthopedists, gynecologists and pediatricians; medical students; and students majoring in biomedical sciences (undergraduate and graduate). Keywords:Bone;Skleton;Osteoclast;Osteoblast;Osteoporosis;RemodelingKey Features:Book covers both classic topics in bone research and new advancesTopics covered represent the most active areas of bone researchContributions from leading experts such as Dr Harold M Frost, regarded by most as the most influential theoretician in skeletal biology in the last fifty years, and Dr Webster S S Jee

Bone Formation

Author: Felix Bronner
Publisher: Springer Science & Business Media
ISBN: 9781852337179
Size: 66.69 MB
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Bone research in recent years has generated much new knowledge, in large measure because of the broad public health implications of osteoporosis and related bone disorders. Bone Formation, the first in a series entitled Topics in Bone Biology, evaluates this new information and formulates novel insights and hypotheses within the broad framework of current knowledge. An easy-to handle and to read work, with concise reviews that are extensively referenced, the chapters in this book are written by internationally known authorities. Particular emphasis is on osteoporosis and related disorders of diminished bone formation. Among the general topics treated is a chapter on biomechanical aspects of bone formation, not often considered in relation to diseases of bone formation. The book constitutes essential reading for those entering the field of bone biology and those who wish to become familiar with up-to-date information in a particular area of bone research.

Current Topics In Bone Biology

Author: Hong-wen Deng
Publisher: World Scientific
ISBN: 9812562095
Size: 56.18 MB
Format: PDF, ePub, Mobi
View: 1050
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This book covers a wide spectrum of areas related to basic bone research. While bone remodeling, bone development, and osteoclast biology constitute the main contents, topics important to the understanding of bone metabolism and treatment of bone-related diseases are also intensively reviewed. Three chapters are dedicated to the classic topic of bone mechanics, which include a brief overview of the mechanostat hypothesis, a more detailed review on mechanotransduction and bone adaptation, and a chapter illustrating the basic principles of bone mechanical testing. New emerging fields such as skeletal stem cells, bone tissue engineering, phytoestrogens applications, and bone genetics study using mouse models, are also covered in detail. The book closes with a special chapter dedicated to state-of-the-art advances in bone biology research.

Principles Of Bone Biology

Author: John P. Bilezikian
Publisher: Academic Press
ISBN: 9780080568751
Size: 39.70 MB
Format: PDF
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Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition

Current Topics In Developmental Biology

Author:
Publisher: Elsevier
ISBN: 0080458300
Size: 77.53 MB
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Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology. This volume contains nine important contributions from leading minds in developmental biology. Presents major contemporary issues and astonishing discoveries at the forefront of modern developmental biology, stem cells, cloning, and regenerative medicine Series Editor, Gerald Schatten, is one of the leading minds in reproductive and developmental science The longest-running forum for current issues in developmental biology with over 30 years of coverage

Bones And Cartilage

Author: Brian K. Hall
Publisher: Academic Press
ISBN: 0124166857
Size: 46.99 MB
Format: PDF, Kindle
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Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Dynamics Of Bone And Cartilage Metabolism

Author: Markus J. Seibel
Publisher: Elsevier
ISBN: 9780080456263
Size: 67.26 MB
Format: PDF
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This updated edition is a comprehensive treatise that spans the complete range of basic biochemistry of bone and cartilage components to the clinical evaluation of disease markers in bone and joint disorders. With contributions from over 75 international experts, Dynamics of Bone and Cartilage Metabolism, Second Edition, is indispensable reading for those involved in skeletal research as well as for rheumatologists, endocrinologists, clinical biochemists, and other clinical disciplines participating in the management of patients with bone and cartilage diseases. Part I provides an up-to-date account of current knowledge of the structure, biosynthesis and molecular biology of the major tissue components Part II covers the organizational structure and cellular metabolism of bone and cartilage Part III deals with the utility of components specific to bone and cartilage as biomarkers of health and disease