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Chronic Inflammation

Author: Sashwati Roy
Publisher: CRC Press
ISBN: 1439872155
Size: 75.15 MB
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Although acute inflammation is a healthy physiological response indicative of wound healing, chronic inflammation has been directly implicated in a wide range of degenerative human health disorders encompassing almost all present day non-communicable diseases including autoimmune diseases, obesity, diabetes and atherosclerosis. Chronic Inflammation: Molecular Pathophysiology, Nutritional and Therapeutic Interventions provides an exposition of the process of chronic inflammation in three parts: Systems Biology of Inflammation and Regulatory Mechanisms describes the process of chronic inflammation including initiation, progression, and resolution. Pathologies Associated with Inflammation gives a rigorous and critical treatment of specific human health disorders where chronic inflammation plays a major role. Nutrition & Therapeutics for Inflammatory Diseases details the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, NSAIDs, disease modifying anti-rheumatic drugs, and novel regimens. Designed for scientists as well as clinicians, Chronic Inflammation provides critical understanding of the key checkpoints that regulate chronic inflammation. Going beyond the epidemiology of chronic inflammation, the text covers regulatory mechanisms controlling inflammation initiation, progression, and resolution. The authors address pathologies associated with inflammation and provide various nutritional and therapeutic interventions for inflammatory diseases.

Nutritional And Therapeutic Interventions For Diabetes And Metabolic Syndrome

Author: Debasis Bagchi
Publisher: Academic Press
ISBN: 0128120088
Size: 29.46 MB
Format: PDF
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Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome, Second Edition, provides an overview of the current diabetes epidemic, outlines the consequences of this crisis, and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. Contributing experts provide up-to-date global approaches to the critical consequences of metabolic syndrome and make the book an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer’s and neurodegenerative diseases, roles of SGLT2 inhibitors in the treatment of type 2 diabetes, novel biomarkers in diabetes, roles of Trigonella foenum-graecumseed extract in type 2 diabetes, beneficial effects of chromium (III) and vanadium supplements in diabetes, prevention of type 1 diabetes, novel drugs in the therapeutic intervention of type 2 diabetes, eHealth and mobile apps for self-management, artificial pancreatic transplantation, non-invasive glucose monitoring, and the app for glucose regulation. Contains a scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions, plus both Type I and Type II Diabetes Presents both prevention and treatment options

Biomarkers Of Cardiometabolic Risk Inflammation And Disease

Author: Filipe Palavra
Publisher: Springer
ISBN: 3319160184
Size: 79.16 MB
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This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders. Tackling the topic in a systematic manner, the book starts with an introduction to cardiometabolic risk and its clinical relevance, comparing emergent and classical biomarkers. It then goes on to discuss cardiometabolic risk biomarkers in a range of diseases, including diabetes, ischemic stroke and neurodegenerative disorders. Biomarkers of Cardiometabolic Risk, Inflammation and Disease is aimed at doctors specializing in internal medicine, neurology, cardiology, rheumatology, nephrology or endocrinology and will also be of interest to GPs, trainee doctors and clinical and basic researchers working on cardiovascular and autoimmune disorders.

Lipid Oxidation In Health And Disease

Author: Corinne M. Spickett
Publisher: CRC Press
ISBN: 1482202867
Size: 64.30 MB
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Oxidative modification of lipids and phospholipids—including radical damage, halogenation, and nitration—result in significant changes to the chemical properties of the molecules, which in turn have a major effect on their biochemical functions. Lipid oxidation has long been regarded as a deleterious process responsible for lipid rancidity, loss of function, and generation of toxic products. However in recent years, research has also focused on the non-detrimental physiological and pathological effects of these chemical reactions. Lipid Oxidation in Health and Disease provides an up-to-date review of the role of oxidized lipid products in physiological and pathophysiological processes. Covering the diverse topics that contribute to research in this important field, this book explores: The mechanisms of lipid oxidation, both enzymatic and non-enzymatic Antioxidant defenses and lipid oxidation Lipid oxidation products and cell signaling The roles of oxidized lipids in specific diseases—including cardiovascular, neurodegenerative, and metabolic disorders, as well as in cancer Drug targeting and the therapeutic potential of oxidized lipids Accurate measurement of the formation of lipid oxidation products and investigation of their biological effects and roles in disease are critical to biomedical science and new targeted therapeutics. Written by acknowledged experts in the field, this book provides a broad survey of both established knowledge and recent findings on the action of oxidized lipid products on cell signaling and gene expression in health and disease.

Bioactive Food As Dietary Interventions For Arthritis And Related Inflammatory Diseases

Author: Ronald Ross Watson
Publisher: Academic Press
ISBN: 012397156X
Size: 73.37 MB
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Antioxidant flavonoids for arthritis treatment : Human and animal models / S.G. Somasundaram, B. Oommen -- Inflammation in arthritis / N.J. Correa-Matos, S.B. Vaghefi -- Effects of beef on inflammation affecting arthritis / A.E. Galena -- Contribution of bioactive foods and their emerging role in immunomodulation, inflammation, and arthritis / N. Khan ... [et al.] -- Curcumin and joint health : From traditional knowledge to clinical validation / S. Togni, G. Appendino -- Dried plum and bone health / B.J. Smith, E. Rendina, E.A. Lucas -- The alkaline way : Integrative management of rheumatoid arthritisand other autoimmune conditions / R. Jaffe -- Marine omega-3 polyunsaturated fatty acids and rheumatoid arthritis / P.C. Calder -- Diet modulated inflammation in chronic disease : An overview / G. Egger -- Food supplements and immune function in humans / J. Romeo ... [et al.] -- Natural antioxidants and resistance to infection / M.A. Puertollano ... [et al.] -- The effects of flavonoids on ...

Cardiovascular Diseases

Author: Nilanjana Maulik, Ph.D.
Publisher: CRC Press
ISBN: 1439882010
Size: 55.50 MB
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With cardiovascular disease remaining one of the primary causes of morbidity and mortality worldwide, there is a great need to further understand the molecular basis of this disease class and develop new therapeutic or preventative measures. Cardiovascular Diseases: Nutritional and Therapeutic Interventions presents up-to-date information on the pathobiology of cardiovascular diseases, emphasizing emerging therapeutics and nutritional interventions. The book is divided into four parts: epidemiology, epigenetics, pathobiology, and therapies for cardiovascular diseases. Part I details epidemiological studies, highlighting the extent of the clinical problem. Part II describes the genetic and, primarily, epigenetic modifications associated with cardiovascular disease, including the importance of DNA methylation status and the possibility of early intervention using simple dietary modifications. The text also discusses histone modifications associated with disease and potential therapeutic synthetic and dietary compounds such as resveratrol and garlic. Covering the etiology and pathobiology, part III discusses lipid regulation, micro-RNAs, emerging cell-based therapies, and new receptor targets for therapeutics as well as targeted imaging. It also describes the link between cancer therapies and cardiomyopathy and the potential of vitamin C to ameliorate this effect. Part IV focuses on therapeutic and nutritional interventions, namely, stem cell therapies, emerging nanomedicines, and a wide range of dietary interventions. These include general healthy diets, fruits and vegetables, botanicals, effects of specific compounds such as antioxidants, and discussions on garlic, curcumin, and resveratrol. The text also covers lifestyle factors, emphasizing the importance of stress in the occurrence of and meditation and yoga in the management of cardiovascular disease. This book provides a comprehensive reference for clinicians and scientists, combining epidemiology, prevention, and modern treatment strategies.

Inflammation In The Pathogenesis Of Chronic Diseases

Author: Randall E. Harris
Publisher: Springer Science & Business Media
ISBN: 1402056885
Size: 74.20 MB
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In this book, a worldwide panel of leading experts discuss the role of inflammation in the pathogenesis of major chronic diseases and the current controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. The authors provide exciting and enlightening perspectives on COX-2 and related molecular targets in the future of medicine, including historical perspectives.

Clinical Naturopathy

Author: Jon Wardle
Publisher: Elsevier Health Sciences
ISBN: 0729579263
Size: 67.34 MB
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A landmark guide to naturopathic practice in Australia – ideal for naturopaths, naturopathy students and Allied Health and medical practitioners Clinical Naturopathy: An evidence-based guide to practice details key treatment protocols and evidence-based complementary medicine interventions for use in naturopathic practice. This valuable naturopathy resource is authored by leading practitioners in the field. Its unique perspective combines clinical experience with evidence-based substantiation from rigorous medical research. Clinical Naturopathy explores key naturopathic treatments – including herbal treatments, nutritional and dietary treatments and lifestyle treatments – for common medical symptoms and conditions encountered in modern practice. Clinical Naturopathy: An evidence-based guide to practice outlines an introduction to case-taking methodology and naturopathic diagnostic techniques. It then details treatment protocols and naturopathic prescriptions to treat major health conditions within individual body systems. The textbook also offers special sections on naturopathic treatment throughout the life cycle, including paediatrics, pregnancy and aging, as well as complex health conditions like HIV, cancer and pain management. Comprehensive appendices provide additional clinically important material, such as reference levels for laboratory medical tests, nutrient food values and traditional Chinese medical diagnosis. This one-of-a-kind naturopathic reference makes essential reading for practitioners wishing to enhance practical application of their skills in a clinical setting, and advance their knowledge of evidence-based complementary medicine interventions. • addresses pre-clinical and clinical naturopathy subjects (from third year naturopathy to post-graduate level) • focuses on major medical conditions, and outlines naturopathic and integrative medical treatments • features case studies to contextualise theory into relevant clinical application • includes user-friendly clinical decision trees, tables and figures • is rigorously researched with over 4000 references

Inflammation Advancing Age And Nutrition

Author: Irfan Rahman
Publisher: Academic Press
ISBN: 0123978076
Size: 28.17 MB
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The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. Includes models of aging, including worm, mouse and human Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition Includes suggested nutritional interventions

Copd An Issue Of Clinics In Chest Medicine

Author: Peter J Barnes
Publisher: Elsevier Health Sciences
ISBN: 0323260918
Size: 30.33 MB
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This issue of Clinics in Chest Medicine is Guest Edited by Peter J. Barnes FRS, FMedSci from Imperial College London and will fosus on COPD. Article topics include epidemiology, pathophysiology, cellular and molecular mechanisms and comorbidities of COPD, diagnosis and phenotype of COPD, pulmonary rehabilitation, asthma and COPD, biomarkers, bronchodilators, non invasive ventialtion, and new drug therapies.