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Computational Biology

Author: Röbbe Wünschiers
Publisher: Springer Science & Business Media
ISBN: 3642347495
Size: 33.46 MB
Format: PDF
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This greatly expanded 2nd edition provides a practical introduction to - data processing with Linux tools and the programming languages AWK and Perl - data management with the relational database system MySQL, and - data analysis and visualization with the statistical computing environment R for students and practitioners in the life sciences. Although written for beginners, experienced researchers in areas involving bioinformatics and computational biology may benefit from numerous tips and tricks that help to process, filter and format large datasets. Learning by doing is the basic concept of this book. Worked examples illustrate how to employ data processing and analysis techniques, e.g. for - finding proteins potentially causing pathogenicity in bacteria, - supporting the significance of BLAST with homology modeling, or - detecting candidate proteins that may be redox-regulated, on the basis of their structure. All the software tools and datasets used are freely available. One section is devoted to explaining setup and maintenance of Linux as an operating system independent virtual machine. The author's experiences and knowledge gained from working and teaching in both academia and industry constitute the foundation for this practical approach.

Computational Biology

Author: Röbbe Wünschiers
Publisher: Springer Science & Business Media
ISBN: 3642185525
Size: 68.28 MB
Format: PDF, Docs
View: 7313
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-Teaches the reader how to use Unix, which is the key to basic computing and allows the most flexibility for bioinformatics applications -Written specifically with the needs of molecular biologists in mind -Easy to follow, written for beginners with no computational knowledge -Includes examples from biological data analysis -Can be use either for self-teaching or in courses

A First Course In Systems Biology

Author: Eberhard Voit
Publisher: Garland Science
ISBN: 1351332945
Size: 19.81 MB
Format: PDF, Docs
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A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling, then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way, it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks, understanding the modern literature, and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design, limit cycles and chaos, parameter estimation in Excel, model representations of gene regulation through transcription factors, derivation of the Michaelis-Menten rate law from the original conceptual model, different types of inhibition, hysteresis, a model of differentiation, system adaptation to persistent signals, nonlinear nullclines, PBPK models, and elementary modes. The format is a combination of instructional text and references to primary literature, complemented by sets of small-scale exercises that enable hands-on experience, and large-scale, often open-ended questions for further reflection.

Computational Genome Analysis

Author: Richard C. Deonier
Publisher: Springer Science & Business Media
ISBN: 9780387987859
Size: 46.54 MB
Format: PDF, Mobi
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This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.

Practical Computing For Biologists

Author: Steven Harold David Haddock
Publisher: Sinauer Associates Incorporated
ISBN: 9780878933914
Size: 45.56 MB
Format: PDF, ePub
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To help with the increasingly large data sets that many scientists deal with, this book illustrates how to use many freely available computing tools to work more powerfully and effectively. The book was born out of the authors' experiences developing tools for their research and to fix other biologist's computational problems.

Doing Data Science

Author: Cathy O'Neil
Publisher: "O'Reilly Media, Inc."
ISBN: 144936389X
Size: 27.49 MB
Format: PDF, Mobi
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Now that people are aware that data can make the difference in an election or a business model, data science as an occupation is gaining ground. But how can you get started working in a wide-ranging, interdisciplinary field that’s so clouded in hype? This insightful book, based on Columbia University’s Introduction to Data Science class, tells you what you need to know. In many of these chapter-long lectures, data scientists from companies such as Google, Microsoft, and eBay share new algorithms, methods, and models by presenting case studies and the code they use. If you’re familiar with linear algebra, probability, and statistics, and have programming experience, this book is an ideal introduction to data science. Topics include: Statistical inference, exploratory data analysis, and the data science process Algorithms Spam filters, Naive Bayes, and data wrangling Logistic regression Financial modeling Recommendation engines and causality Data visualization Social networks and data journalism Data engineering, MapReduce, Pregel, and Hadoop Doing Data Science is collaboration between course instructor Rachel Schutt, Senior VP of Data Science at News Corp, and data science consultant Cathy O’Neil, a senior data scientist at Johnson Research Labs, who attended and blogged about the course.

40 Days Of Dating

Author: Timothy Goodman
Publisher: ABRAMS
ISBN: 1613127154
Size: 27.70 MB
Format: PDF, ePub
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“What would happen if Harry met Sally in the age of Tinder and Snapchat? . . . A field guide to Millennial dating in New York City” (New York Daily News). When New York–based graphic designers and long-time friends Timothy Goodman and Jessica Walsh found themselves single at the same time, they decided to try an experiment. The old adage says that it takes 40 days to change a habit—could the same be said for love? So they agreed to date each other for 40 days, record their experiences in questionnaires, photographs, videos, texts, and artworks, and post the material on a website they would create for this purpose. What began as a small experiment between two friends became an Internet sensation, drawing 5 million unique (and obsessed) visitors from around the globe to their site and their story. 40 Days of Dating: An Experiment is a beautifully designed, expanded look at the experiment and the results, including a great deal of material that never made it onto the site, such as who they were as friends and individuals before the 40 days and who they have become since.

Information And Communication Technology For Sustainable Development

Author: Durgesh Kumar Mishra
Publisher: Springer
ISBN: 9811039321
Size: 48.87 MB
Format: PDF, ePub, Docs
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The book proposes new technologies and discusses future solutions for design infrastructure for ICT. The book contains high quality submissions presented at Second International Conference on Information and Communication Technology for Sustainable Development (ICT4SD - 2016) held at Goa, India during 1 - 2 July, 2016. The conference stimulates the cutting-edge research discussions among many academic pioneering researchers, scientists, industrial engineers, and students from all around the world. The topics covered in this book also focus on innovative issues at international level by bringing together the experts from different countries.

Data Driven Innovation Big Data For Growth And Well Being

Author: OECD
Publisher: OECD Publishing
ISBN: 9264229353
Size: 56.89 MB
Format: PDF, Docs
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This report improves the evidence base on the role of Data Driven Innovation for promoting growth and well-being, and provide policy guidance on how to maximise the benefits of DDI and mitigate the associated economic and societal risks.

Software Tools And Algorithms For Biological Systems

Author: Hamid Arabnia
Publisher: Springer Science & Business Media
ISBN: 1441970460
Size: 73.55 MB
Format: PDF, Docs
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“Software Tools and Algorithms for Biological Systems" is composed of a collection of papers received in response to an announcement that was widely distributed to academicians and practitioners in the broad area of computational biology and software tools. Also, selected authors of accepted papers of BIOCOMP’09 proceedings (International Conference on Bioinformatics and Computational Biology: July 13-16, 2009; Las Vegas, Nevada, USA) were invited to submit the extended versions of their papers for evaluation.