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Cracking The Aging Code

Author: Josh Mitteldorf
Publisher: Flatiron Books
ISBN: 1250061725
Size: 21.31 MB
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A revolutionary examination of why we age, what it means for our health, and how we just might be able to fight it. In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction. When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection. This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.

Cracking The Aging Code

Author: Josh Mitteldorf
Publisher: Macmillan
ISBN: 1250061709
Size: 66.26 MB
Format: PDF, Docs
View: 5095
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A revolutionary examination of why we age, what it means for our health, and how we just might be able to fight it. In Cracking the Aging Code, theoretical biologist Josh Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction. When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection. This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.

Cracking The Aging Code

Author: Josh Mitteldorf
Publisher: Flatiron Books
ISBN: 9781250061713
Size: 56.97 MB
Format: PDF, Docs
View: 2011
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What is the function of aging? Why do most, but not all species age? Aging is generally thought of as wear and tear, but why does this process occur if there is no benefit for the individual? If the selfish gene and natural selection is at play, then why do our cells die off? In Cracking the Aging Code , theoretical biologist Joshua Mitteldorf and award-winning writer and ecological philosopher Dorion Sagan reveal that evolution and aging are even more complex and breathtaking than we originally thought. Using an in-depth and wide-ranging review of the biological record and exploring the genes that either start or stall aging the authors challenge the assumptions of neo-Darwinism and show us how aging evolved not to help ourselves and those like us, but to support the "greater good." Our genetically pre-programmed death is ultimately a means to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction. This dynamic new understanding of aging opens the door to startling new means of stopping, slowing, or reversing the aging process. A controversial, idea-driven book that is at once provocative, entertaining and pioneering, Cracking the Aging Code challenges the way we understand aging, death, and just what makes us human.

Why We Age

Author: Steven N. Austad
Publisher: Wiley
ISBN: 9780471296461
Size: 60.84 MB
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Why has the life span of the average American increased from 48 to 75 years in this century alone? . . . If the body is a machine that simply wears out, why do some cells seem immortal? . . . Is there an aging gene? And can we control it? . . . Can antioxidants and hormone therapy actually slow the aging process and extend life? Steven Austad s compelling book investigates the history, the theories, and the personalities behind the quest to understand the nature of aging. Here is hard evidence from the front lines of research that science is finally closing in on the fundamental processes of human biology and life. "Austad s book can be read with pleasure and profit by any intelligent person with a smattering of biological knowledge." Science "In this clear, engrossing overview, Austad takes the sting out of a subject that will ultimately capture us all." Publishers Weekly "Why We Age is remarkably rigorous in its analysis and thorough scope. . . . A comprehensive examination of its topic." Science Editors, Amazon.com "The problem with long life is that one keeps getting older; here s an able and clearly written summary of the latest theories on why we age and what might be done to ameliorate the process." Kirkus Reviews

The Youth Pill

Author: David Stipp
Publisher: Penguin
ISBN: 110144228X
Size: 31.92 MB
Format: PDF
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In The Youth Pill, journalist David Stipp explores the scientific battle against aging and the pioneers of the movement to extend lifespan for everyone. He takes readers behind the scenes and introduces us to the key players who are experimenting with the most promising cutting-edge research. It is an informative and provocative read that shows how a small group of optimistic and determined scientists are closing in on drugs that will change the way we live forver.

Ageless Quest

Author: Leonard Guarente
Publisher: CSHL Press
ISBN: 9780879696528
Size: 48.65 MB
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Ageless Questis a personal, sometimes controversial, account of the pursuit of a genetic †̃cure' for aging by an expert in the field. The author is the Novartis Professor of Biology at the Massachusetts Institute of Technology. Aging has always been regarded as a highly complex process with many degenerative changes leading to the cessation of life. But recent research has identified a relatively simple mechanism that governs the pace of aging. Lenny Guarente's Ageless Questis a scientific detective story for the baby boom generation. It offers an insider's view of an area of potentially astonishing high reward—and equally high risk.

Into The Cool

Author: Eric D. Schneider
Publisher: University of Chicago Press
ISBN: 0226739368
Size: 38.32 MB
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Demonstrates how the second law of thermodynamics--which refers to energy's tendency to change from being concentrated in one place to being spread out over time--is behind evolution, ecology, economics, and even the origins of life itself in this scientific tour de force that explores how complex systems emerge, enlarge, and reproduce in a chaotic world.

Cosmic Apprentice

Author: Dorion Sagan
Publisher:
ISBN: 9780816684373
Size: 27.35 MB
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Refreshingly nonconformist and polemically incisive, "Cosmic Apprentice "challenges readers to reject both dogma and clich(r) and instead recover the intellectual adventurousness that shouldOCoand can once againOCoanimate both science and philosophy. Informed by a countercultural sensibility, a deep engagement with speculative thought, and a hardheaded scientific skepticism, it advances controversial positions on such seemingly sacrosanct subjects as evolution and entropy.

Apoptosis And Beyond

Author: James Radosevich
Publisher: Wiley-Blackwell
ISBN: 1119432421
Size: 72.26 MB
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These volumes teach readers to think beyond apoptosis and describes all of the known processes that cells can undergo which result in cell death This two-volume source on how cells dies is the first, comprehensive collection to cover all of the known processes that cells undergo when they die. It is also the only one of its kind to compare these processes. It seeks to enlighten those in the field about these many processes and to stimulate their thinking at looking at these pathways when their research system does not show signs of activation of the classic apoptotic pathway. In addition, it links activities like the molecular biology of one process (eg. Necrosis) to another process (eg. apoptosis) and contrasts those that are close to each. Volume 1 of Apoptosis and Beyond: The Many Ways Cells Die begins with a general view of the cytoplasmic and nuclear features of apoptosis. It then goes on to offer chapters on targeting the cell death mechanism; microbial programmed cell death; autophagy; cell injury, adaptation, and necrosis; necroptosis; ferroptosis; anoikis; pyronecrosis; and more. Volume 2 covers such subjects as phenoptosis; pyroptosis; hematopoiesis and eryptosis; cyclophilin d-dependent necrosis; and the role of phospholipase in cell death. Covers all known processes that dying cells undergo Provides extensive coverage of a topic not fully covered before Offers chapters written by top researchers in the field Provides activities that link and contrast processes to each other Apoptosis and Beyond: The Many Ways Cells Die will appeal to students and researchers/clinicians in cell biology, molecular biology, oncology, and tumor biology.