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Cytoskeletal Mechanics

Author: Mohammad R. K. Mofrad
Publisher: Cambridge University Press
ISBN: 9781107648289
Size: 32.59 MB
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This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors of this book come from the biophysics, bioengineering, and physical chemistry communities and each joins the discussion with a unique perspective on biological systems. Consequently, the approaches range from finite element methods commonly used in continuum mechanics to models of the cytoskeleton as a cross-linked polymer network to models of glassy materials and gels. Studies reflect both the static, instantaneous nature of the structure, as well as its dynamic nature due to polymerization and the full array of biological processes. While it is unlikely that a single unifying approach will evolve from this diversity, it is our hope that a better appreciation of the various perspectives will lead to a highly coordinated approach to exploring the essential problems and better discussions among investigators with differing views.

Fundamentals Of Biomechanics

Author: Nihat Özkaya
Publisher: Springer
ISBN: 3319447386
Size: 22.60 MB
Format: PDF
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This textbook integrates the classic fields of mechanics—statics, dynamics, and strength of materials—using examples from biology and medicine. The book is excellent for teaching either undergraduates in biomedical engineering programs or health care professionals studying biomechanics at the graduate level. Extensively revised from a successful third edition, Fundamentals of Biomechanics features a wealth of clear illustrations, numerous worked examples, and many problem sets. The book provides the quantitative perspective missing from more descriptive texts, without requiring an advanced background in mathematics. It will be welcomed for use in courses such as biomechanics and orthopedics, rehabilitation and industrial engineering, and occupational or sports medicine. This book: Introduces the fundamental concepts, principles, and methods that must be understood to begin the study of biomechanics Reinforces basic principles of biomechanics with repetitive exercises in class and homework assignments given throughout the textbook Includes over 100 new problem sets with solutions and illustrations

Introductory Biomechanics

Author: C. Ross Ethier
Publisher: Cambridge University Press
ISBN: 1139461826
Size: 47.93 MB
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Introductory Biomechanics is a new, integrated text written specifically for engineering students. It provides a broad overview of this important branch of the rapidly growing field of bioengineering. A wide selection of topics is presented, ranging from the mechanics of single cells to the dynamics of human movement. No prior biological knowledge is assumed and in each chapter, the relevant anatomy and physiology are first described. The biological system is then analyzed from a mechanical viewpoint by reducing it to its essential elements, using the laws of mechanics and then tying mechanical insights back to biological function. This integrated approach provides students with a deeper understanding of both the mechanics and the biology than from qualitative study alone. The text is supported by a wealth of illustrations, tables and examples, a large selection of suitable problems and hundreds of current references, making it an essential textbook for any biomechanics course.

Mechanics Of The Cell

Author: David Boal
Publisher: Cambridge University Press
ISBN: 1139501771
Size: 23.24 MB
Format: PDF, ePub
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Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With around 280 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/Boal.

Biology And Engineering Of Stem Cell Niches

Author: Ajaykumar Vishwakarma
Publisher: Academic Press
ISBN: 0128027568
Size: 29.42 MB
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Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type. Includes the importance of Cell-Cell and Cell Matrix Interactions in each specific tissue and system Authored and edited by authorities in this emerging and multidisciplinary field Includes valuable links to 5-10 minute YouTube© author videos that describe main points

Biomedical Engineering

Author: W. Mark Saltzman
Publisher: Cambridge University Press
ISBN: 131629868X
Size: 65.76 MB
Format: PDF
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The second edition of this popular introductory undergraduate textbook uses examples, applications, and profiles of biomedical engineers to show students the relevance of the theory and how it can be used to solve real problems in human medicine. The essential molecular biology, cellular biology, and human physiology background is included for students to understand the context in which biomedical engineers work. Updates throughout highlight important advances made over recent years, including iPS cells, microRNA, nanomedicine, imaging technology, biosensors, and drug delivery systems, giving students a modern description of the various subfields of biomedical engineering. Over two hundred quantitative and qualitative exercises, many new to this edition, help consolidate learning, whilst a solutions manual, password-protected for instructors, is available online. Finally, students can enjoy an expanded set of leader profiles in biomedical engineering within the book, showcasing the broad range of career paths open to students who make biomedical engineering their calling.

The Cell As A Machine

Author: Michael Sheetz
Publisher: Cambridge University Press
ISBN: 1107052734
Size: 18.43 MB
Format: PDF, ePub, Docs
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A systematic and mathematically accessible introductory text explaining cell functions through the engineering principles of robust devices.

Cellular Mechanotransduction

Author: Mohammad R. K. Mofrad
Publisher: Cambridge University Press
ISBN: 1316139476
Size: 39.85 MB
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'Mechanotransduction' is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.

Biological Physical And Technical Basics Of Cell Engineering

Author: Gerhard M. Artmann
Publisher: Springer
ISBN: 9811079048
Size: 19.16 MB
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This book presents and discusses recent scientific progress on Cell and Stem Cell Engineering. It predominantly focuses on Biological, Physical and Technical Basics, and features new trends of research reaching far into the 21st century.

An Introduction To Modeling Of Transport Processes

Author: Ashim Datta
Publisher: Cambridge University Press
ISBN: 0521119243
Size: 47.75 MB
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Organised around problem solving, this book introduces the reader to computational simulation, bridging fundamental theory with real-world applications.