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Discovery Of Novel Natural Products With Therapeutic Potential

Author: Vincent P. Gullo
Publisher: Newnes
ISBN: 1483292134
Size: 13.33 MB
Format: PDF, ePub, Mobi
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Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sources of natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

Natural Products In The New Millennium Prospects And Industrial Application

Author: Amelia Rauter
Publisher: Springer Science & Business Media
ISBN: 9401598762
Size: 12.34 MB
Format: PDF, ePub, Docs
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This book deals with a variety of aspects of natural product research. It includes review articles and revised original contributions involving analysis, isolation and structure elucidation, synthesis and bioactivity of terrestrial and marine natural products. Plant cell biotechnology for the production of secondary metabolites is discussed. This volume provides also outstanding information about the industrial application of natural products for medicinal purposes. The broad interdisciplinary approach found in this book, which comprises 50 papers, makes it interesting to the scientists, whose work is in any way related to the research or use of natural products.

Natural Products

Author: Lixin Zhang
Publisher: Springer Science & Business Media
ISBN: 1592599761
Size: 58.98 MB
Format: PDF, Mobi
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A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.

Mycorrhiza

Author: Ajit Varma
Publisher: Springer Science & Business Media
ISBN: 3540788263
Size: 35.19 MB
Format: PDF
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This book is perfectly timed for the worldwide explosion of interest in mycorrhizal research. With a strong emphasis on the latest findings in genetics and molecular biology, it contains all current information and speculation on the structure, function and biotechnological applications of mycorrhizas.

Anticancer Plants Natural Products And Biotechnological Implements

Author: Mohd Sayeed Akhtar
Publisher: Springer
ISBN: 981108064X
Size: 33.18 MB
Format: PDF
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This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Biotechnological Production Of Plant Secondary Metabolites

Author: Ilkay Orhan
Publisher: Bentham Science Publishers
ISBN: 1608051145
Size: 50.22 MB
Format: PDF, ePub, Mobi
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Modern techniques have been developed to overcome problems associated with the extraction of natural products from plants. These techniques include production of secondary metabolites by biotechnological methods such as plant tissue culture and microbial

Frontiers In Drug Design Discovery

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681083558
Size: 47.10 MB
Format: PDF, Kindle
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Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field.

Lead Molecules From Natural Products

Author:
Publisher: Elsevier
ISBN: 9780080459332
Size: 38.30 MB
Format: PDF, ePub
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Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.

Bio Exploitation Of Filamentous Fungi

Author: Stephen B. Pointing
Publisher:
ISBN: 9789628567720
Size: 79.60 MB
Format: PDF, Kindle
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The focus of this exciting new book is on identifying existing and potential applications for filamentous fungi. Selected topics at the forefront of current fungal biotechnology research, namely bioactive compounds and agricultural applications, are covered in depth by acknowledged experts in their field. Other emerging fungal technologies such as bioremediation are also reviewed, together with associated subjects such as the ownership of genetic resources.

Bioactive Natural Products

Author: Goutam Brahmachari
Publisher: John Wiley & Sons
ISBN: 3527337946
Size: 75.90 MB
Format: PDF
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A multi-disciplinary survey of current topics and future trends in natural products research, with a focus on pharmaceutical and medical applications.