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Dna Helicases And Dna Motor Proteins

Author: Maria Spies
Publisher: Springer Science & Business Media
ISBN: 1461450373
Size: 34.86 MB
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In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.

Single Molecule Studies Of Nucleic Acids And Their Proteins

Author: David Bensimon
Publisher: Oxford University Press
ISBN: 0192559966
Size: 16.17 MB
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This book provides the basis for understanding the elastic properties of nucleic acids (DNA, RNA), the methods used to manipulate them (e.g. optical, magnetic and acoustic tweezers and traps), and how to observe their interactions with proteins (e.g. fluorescence microscopy, FCS, FRET, etc.). It then exemplifies the use of these various methods in the study of three families of DNA enzymes: polymerases, helicases and topoisomerases. The book aims not to be exhaustive, but rather to stimulate the imagination of readers in the application of these single molecule approaches to the study of DNA/RNA and their interactions.

Biochemie

Author: Lubert Stryer
Publisher: Vieweg+Teubner Verlag
ISBN: 9783663001096
Size: 70.61 MB
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Das Geschlecht In Der Biologie

Author: Mechthild Koreuber
Publisher: Nomos Verlag
ISBN: 3845239433
Size: 53.10 MB
Format: PDF, Kindle
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Geschlechterforschung in und zur Biologie ist notwendiger denn je, um naturalistischen Vorstellungen über Geschlechterdifferenz und Geschlechterverhältnisse entgegenzutreten und die Fragwürdigkeit von Positionen aufzuzeigen, die glauben, sich auf biologische Erkenntnisse beziehen zu können. Dieser Sammelband beleuchtet das Thema Geschlecht in der Biologie aus unterschiedlichen Perspektiven und liefert konkrete Beispiele.

Medizinische Physik 2

Author: W. Schlegel
Publisher: Springer-Verlag
ISBN: 3642562590
Size: 26.83 MB
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Kompaktes Wissen f? Studium und Weiterbildung aus dem renommierten Heidelberger Kurs f? medizinische Physik.

Gesund Altern

Author: Magdalena M Schimke
Publisher: Springer-Verlag
ISBN: 3658199733
Size: 43.80 MB
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Die Autorinnen und Autoren führen interdisziplinär Wissensbestände zum Thema Altersforschung zusammen. Neben unterschiedlichen Perspektiven bieten sie in kompakten Beiträgen einen Einblick zu Prozessen des Alterns und über Erkenntnisse zu gesundem Altern. Darüber hinaus werden zentrale Ansätze und Modelle diskutiert sowie unterschiedliche disziplinäre Perspektiven zugänglich gemacht. Der rote Faden, der sich durch die Beiträge zieht, ist der Zugang zu gesundem Altern. Kritische Reflexionen und Ausblicke runden den Sammelband ab.

Pl Tzlich War Alles Anders

Author: Daggi Geiselmann
Publisher:
ISBN: 9781985233478
Size: 76.18 MB
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Die Autorin beschreibt in ihrem autobiografischen Roman das Leben in ihrer Wahlheimat Kalabrien.Ein Leben gepr�gt von Zorn, Hass, Verzweiflung, falschen Schuldgef�hlen und der Liebe, die alles auszugleichen schien.Sie zeigt auf, wie gef�hrlich es sein kann, in einem Land der �Ndrangheta, in einem Land der Korruption, in einem Land der fast nicht vorhandenen Gesundheitsvorsorge, die sie Aufgrund ihrer HIV-Erkrankung dringend br�uchte, zu leben.In einer zum Teil ernsten, aber auch heiteren Art, erz�hlt sie aus ihrem Leben, das den Leser in Atem h�lt.Vers�umen sie nicht, die Autorin zu begleiten.

Die Cellularpathologie In Ihrer Begr Ndung Auf Physiologische Und Pathologische Gewebelehre

Author: Rudolf Ludwig Karl Virchow
Publisher: Wentworth Press
ISBN: 9780270274080
Size: 21.47 MB
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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.