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Essential Ion Channel Methods

Author: P. Michael Conn
Publisher: Academic Press
ISBN: 9780123822376
Size: 28.33 MB
Format: PDF
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The rapid growth of interest and research activity in ion channels is indicative of their fundamental importance in the maintenance of the living state. This volume was prepared with a view toward providing a sampling of the range of molecular and physical methods that are significant for the study of ion channels. As part of the Reliable Lab Solutions series, Essential Ion Channel Methods brings together chapters from volumes 293 and 294 of Methods in Enzymology. The chapters have been selected by the editor and updated, when possible, by their original authors to include new research and references. The result is a set of chapters which make use of graphics, comparisons to other methods, and provide tricks and approaches that make it possible to adapt methods to other systems. Methods are presented in a fashion that allows their replication by individuals new to the field, yet providing valuable information for seasoned investigators. Highlights top downloaded and cited chapters, authored by pioneers in the field and enhanced with graphics and easy to follow methods Loaded with detailed protocols developed and used by leaders in the field Refines, organizes and updates popular methods from one of our top selling series, Methods in Enzymology

Essential Bioimaging Methods

Author: P. Michael Conn
Publisher: Academic Press
ISBN: 9780080963426
Size: 10.45 MB
Format: PDF, ePub
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Need a tested, reliable method that works? Put Essential Bioimaging Methods to work for you. Editor Michael Conn has hand-picked the most robust methods from his previously-published volumes in the Methods in Enzymology series. Many of these methods have been briefly updated by the authors that created them and use them in their research, and this book further refines and organizes existing content and focuses on methods that work, including MRI, fMRI, PET, Microscopic optical imaging and other. Part of the Reliable Lab Solution series, this volume provides clear advice and explicit protocols, providing updates to classic, tried-and-true methods and an essential addition to the bookshelf or workbench of any researcher in the field. * Highlights usefulness of techniques in basic research detailing MRI imaging of small animals, fMRI of Macaque monkeys, and baboon model of reperfused stroke * Built from volumes in the flagship brand, Methods in Enzymology * Provides tricks, tips and different approaches

Laboratory And Field Testing Of Unsaturated Soils

Author: Alessandro Tarantino
Publisher: Springer Science & Business Media
ISBN: 1402088191
Size: 38.91 MB
Format: PDF, Kindle
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This volume details recent global advances in laboratory and field testing of unsaturated soils. Coverage includes mechanical, hydraulic, and geo-environmental testing and applications of unsaturated soil monitoring to engineering behavior of geo-structures.

Ion Selective Electrode Method

Author: A.K. Covington
Publisher: CRC Press
ISBN: 1351082329
Size: 64.11 MB
Format: PDF, ePub
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The intention was to produce a book which perforce would never be far from the laboratory, although CRC?s use of Handbook in another connection precludes our use of that word in the title.

Handbook Of Ion Channels

Author: Jie Zheng
Publisher: CRC Press
ISBN: 1466551429
Size: 51.75 MB
Format: PDF, Docs
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The New Benchmark for Understanding the Latest Developments of Ion Channels Ion channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of cells. In nonexcitable tissues, they also help regulate basic salt balance critical for homeostasis. All of these features make ion channels important targets for pharmaceuticals. Handbook of Ion Channels illustrates the fundamental importance of these membrane proteins to human health and disease. Renowned researchers from around the world introduce the technical aspects of ion channel research, provide a modern guide to the properties of major ion channels, and present powerful methods for modeling ion channel diseases and performing clinical trials for ion channel drugs. Conveniently divided into five parts, the handbook first describes the basic concepts of permeation and gating mechanisms, balancing classic theories and the latest developments. The second part covers the principles and practical issues of both traditional and new ion channel techniques and their applications to channel research. The third part organizes the material to follow the superfamilies of ion channels. This part focuses on the classification, properties, gating mechanisms, function, and pharmacology of established and novel channel types. The fourth part addresses ion channel regulation as well as trafficking and distribution. The final part examines several ion channel-related diseases, discussing genetics, mechanisms, and pharmaceutical advances.

Der Lange Weg Zur Freiheit

Author: Nelson Mandela
Publisher: S. Fischer Verlag
ISBN: 3104031541
Size: 48.80 MB
Format: PDF, ePub, Mobi
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»Ich bin einer von ungezählten Millionen, die durch Nelson Mandelas Leben inspiriert wurden.« Barack Obama Eine fast drei Jahrzehnte währende Gefängnishaft ließ Nelson Mandela zum Mythos der schwarzen Befreiungsbewegung werden. Kaum ein anderer Politiker unserer Zeit symbolisiert heute in solchem Maße die Friedenshoffnungen der Menschheit und den Gedanken der Aussöhnung aller Rassen wie der ehemalige südafrikanische Präsident und Friedensnobelpreisträger. Auch nach seinem Tod finden seine ungebrochene Charakterstärke und Menschenfreundlichkeit die Bewunderung aller friedenswilligen Menschen auf der Welt. Mandelas Lebensgeschichte ist über die politische Bedeutung hinaus ein spannend zu lesendes, kenntnis- und faktenreiches Dokument menschlicher Entwicklung unter Bedingungen und Fährnissen, vor denen die meisten Menschen innerlich wie äußerlich kapituliert haben dürften.

Scientific Essentials Of Reproductive Medicine

Author: Stephen G. Hillier
Publisher: Saunders
Size: 76.22 MB
Format: PDF, Kindle
View: 2014
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Addressing the scientific basis of obstetrics and gynaecology in the 1990s, this textbook focuses on the fundamentals of reproductive medicine from the perspective of molecular and cellular biology. It is aimed primarily at trainees, in particular MROG Part 1 candidates.

Steam Water And Hydrothermal Systems

Author: Peter R. Tremaine
Publisher: NRC Research Press
ISBN: 0660177781
Size: 58.69 MB
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This work includes 140 papers on pure and applied research of physics and chemistry of hydrothermal systems. It includes papers on metastable states, nucleation, super-cooled water and high temperature aqueous solutions.

Physiology Of Excitable Membranes

Author: J. Salánki
Publisher: Elsevier
ISBN: 1483146928
Size: 80.30 MB
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Physiology of Excitable Membranes contains plenary lecture and most of the papers presented at five symposia of the Section ""General Cell Physiology"" at the 28th International Congress of Physiological Sciences. Organized into 44 chapters, this book begins with a discussion on the ionic mechanisms of excitability of nerve cells. Subsequent chapters focus on charge movement in nerve membrane; calcium electrogenesis; optical changes during electrogenesis; synaptic transmission and modulation; and transmission in autonomic ganglia.