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Essentials Of Apoptosis

Author: Xiao-Ming Yin
Publisher: Springer Science & Business Media
ISBN: 9781603273817
Size: 39.71 MB
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This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly – chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.

Apoptosis In Health And Disease

Author: Martin Holcik
Publisher: Cambridge University Press
ISBN: 052115944X
Size: 61.68 MB
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A 2005 survey of the role of apoptosis in the pathogenesis of many significant human illnesses and injury states.

Schiff S Diseases Of The Liver

Author: Eugene R. Schiff
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781760409
Size: 37.65 MB
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The premier clinical hepatology reference for 50 years, Schiff's Diseases of the Liver is in its Tenth Edition—now in full color throughout. This edition features a major new transplant section focusing on pre-transplant and post-transplant evaluation and management. Also included are updates on key topics such as hepatitis, NASH, and drug-induced pathologies. The first third of the book covers anatomy, pathology, testing, imaging, and effects of liver disease on other organs. Subsequent sections address specific diseases and clinical syndromes. Each of the 12 sections begins with an overview, and each chapter starts with an outline of key concepts. Numerous clinical algorithms appear throughout the text.

Apoptosis Biology And Mechanisms

Author: Sharad Kumar
Publisher: Springer Science & Business Media
ISBN: 3540691847
Size: 62.44 MB
Format: PDF, ePub
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Apoptosis is currently one of the fastest moving fields in biology with spectacular progress made over the past few years in delineating the molecular It is now indisputable that apoptosis mechanisms which underlie this process. plays an essential role in normal cell physiology and that aberrant apoptosis can manifest itself in a variety of human disorders. Published in two parts (Volumes 23 and 24 of the series entitled Results and Problems in Cell Differen tiation), this is an attempt to bring together many different aspects of apoptosis. Given that this is such a vast and rapidly expanding field, it is almost impossible to cover everything that is now known about apoptosis in two short books, but 1 hope these volumes prove to be a guidepost, providing basic essential information on the biology and molecular mechanisms of apoptosis and its implications in some human diseases. As a significant am o unt of new information on apoptosis is emerging every week, it is unrealistic to expect that by the time these two books are published, all the articles will deliver up-to-date information. Nevertheless, 1 believe that the fundamentals of the apoptotic phenomenon are now firmly in place and are discussed at length in various chapters. Readers may find a small degree of overlap between some chapters. This was unavoidable since closely related areas of apoptosis research have been covered by more than one author.

Vaccinology

Author: Gregg N. Milligan
Publisher: John Wiley & Sons
ISBN: 111863652X
Size: 73.54 MB
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Vaccinology: An Essential Guide outlines in a clear,practical format the entire vaccine development process, fromconceptualization and basic immunological principles through toclinical testing and licensing of vaccines. With anoutstanding introduction to the history and practice ofvaccinology, it also guides the reader through the basic sciencerelating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economicand geographical issues that drive vaccine development and trials,it also presents vaccine delivery strategies, novel vaccineplatforms (including experimental vaccines and pathogens), antigendevelopment and selection, vaccine modelling, and the developmentof vaccines against emerging pathogens and agents of bioterror.There are also sections devoted to veterinary vaccines andassociated regulatory processes. Vaccinology: An Essential Guide is a perfect tool fordesigned for undergraduate and graduate microbiologists andimmunologists, as well as residents, fellows and trainees ofinfectious disease and vaccinology. It is also suitable for allthose involved in designing and conducting clinical vaccine trials,and is the ideal companion to the larger reference bookVaccinology: Principles and Practice.

Oncology Of Infancy And Childhood E Book

Author: Stuart H. Orkin
Publisher: Elsevier Health Sciences
ISBN: 1437721389
Size: 32.27 MB
Format: PDF, ePub
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To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two fields. This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. Written by the leading names in pediatric oncology, this resource is an essential tool for all who care for pediatric cancer patients. Offers comprehensive coverage of all pediatric cancers, including less common tumors, making this the most complete guide to pediatric cancer. Covers emerging research developments in cancer biology and therapeutics, both globally and in specific pediatric tumors. Includes a section on supportive care in pediatric oncology, written by authors who represent the critical subdisciplines involved in this important aspect of pediatric oncology. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines. Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.

Contemporary Management Of Esophageal Malignancy An Issue Of Surgical Clinics E Book

Author: Chad Denlinger
Publisher: Elsevier Health Sciences
ISBN: 1455747920
Size: 17.43 MB
Format: PDF, Docs
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An important review on esophageal neoplasms for the general surgeon! Topics will include epidemiology and prevalence of esophageal cancer, molecular basis of esophageal cancer development and progression, diagnosis and management of Barrett's esophagus, evaluation and staging of patients with esophageal cancer, medical evaluation of patients preparing for an esophagectomy, management of stage 1 esophageal cancer, management of T2 esophageal cancer, management of advanced stage operable esophageal cancer, management of GE junction tumors, traditional esophagectomy surgical techniques, minimally invasive esophagectomy techniques, esophageal reconstruction with alternative conduits, complications of esophagectomy, quality of life after an esophagectomy, palliation of inoperable esophageal cancer and more!