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Forensic Dna Biology

Author: Kelly M. Elkins
Publisher: Academic Press
ISBN: 0123945852
Size: 47.92 MB
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A collection of forensic DNA typing laboratory experiments designed for academic and training courses at the collegiate level.

Forensic Dna Analysis

Author: J. Thomas McClintock
Publisher: CRC Press
ISBN: 1420063308
Size: 42.71 MB
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In its short but active history, the use of DNA typing has revolutionized criminal investigations. It is almost inconceivable to bring a case to trial without positive identification through what is now our most accurate means. Proficiency with the methodology, principles, and interpretation of DNA evidence is crucial for today’s criminalist. An introductory text, Forensic DNA Analysis: A Laboratory Manual presents a contextual history and overview of the science and use of DNA typing. Logically organized, with clear, concise language, this manual provides a fundamental understanding of forensic DNA analysis and a thorough background in the molecular techniques used to determine an individual’s identity. Students are provided with a sound working knowledge of the investigative methodology, scientific principles, and the analysis and interpretation of the resulting data. After laying a foundation on the rules of the laboratory, the basic scientific principles, and the types of biological materials, such as hair, blood, and bone, this practical, hands-on manual provides 12 exercises outlining techniques commonly used in DNA typing. Designed to be performed in a common laboratory, the experiments cover DNA extraction, concentration, and assessment; DNA analysis using restriction fragment length polymorphisms; polymerase chain reaction and PCR-based typing tests; short tandem repeat analysis; and mitochondrial DNA analysis. Many of the procedures described have been adapted from methods used in federal, state, and private forensic laboratories and are suitable to a wide range of applications. There is also an extensive glossary for DNA typing terminology and basic terms used in molecular biology. Instilling confidence, analytical clarity, and a sense of curiosity, this comprehensive introduction is the perfect tool for grasping the techniques and applications of forensic DNA analysis and exploring the questions and issues involved in forensic science investigations.

Funktionelle Ultrastruktur

Author: Margit Pavelka
Publisher: Springer-Verlag
ISBN: 3211308261
Size: 49.33 MB
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Mit dem Blick auf die Feinstrukturen werden die Innenräume der Zellen und ihre Architekturen in der höheren Organisation der Gewebe lebendig. Die Autoren geben mit diesem Atlas der funktionellen Ultrastruktur Einblick in die komplexe zelluläre Innenwelt mit ihren vielgestaltigen Funktionsräumen, sowie in dynamische Funktionsabläufe, die für die Erfüllung der zellulären Aufgaben im Gewebe notwendig sind. Das besondere Anliegen besteht darin, dem Leser bewusst zu machen, dass es sich hier um diejenigen Strukturen handelt, in denen sich grundlegende zelluläre Lebensvorgänge und krankmachende Mechanismen abspielen. An Hand elektronenmikroskopischer Bilder, ergänzt durch Immunelektronenmikroskopie und ausführlicher Beschreibung werden in den Zellen die Beziehungen zwischen Strukturen und Funktionen aufgerollt, Details herausgearbeitet und die Organisation in den Zellverbänden der Gewebe präsentiert. Das Buch wendet sich an Medizin- und Naturwissenschaftsstudenten, Ärzte, Biologen, Zell- und Molekularbiologen.

Csi Forensik F R Dummies

Author: Douglas P. Lyle
Publisher: John Wiley & Sons
ISBN: 3527704698
Size: 40.43 MB
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CSI, CSI Miami, CSI New York, Crossing Jordan: Der Ermittler von heute ist Wissenschaftler, klug und manchmal exzentrisch. So ist das zumindest im Fernsehen, aber wie sieht es in der Wirklichkeit aus? Wie erkennt man an einer Schädelverletzung die Todesursache, wie funktioniert die Untersuchung von Projektilen, welche Möglichkeiten bietet die DNA-Analyse? Douglas P. Lyle klärt Sie in diesem preisgekrönten Buch über die Arbeit der Kriminaltechniker auf und stellt Ihnen bekannte und kuriose Fälle sowie deren Lösung vor.

Forensic Dna Profiling Protocols

Author: Patrick J. Lincoln
Publisher: Springer Science & Business Media
ISBN: 0896034437
Size: 37.49 MB
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In Forensic DNA Profiling Protocols, leading forensic experts from around the world describe in detail their time-proven methods for identity testing through DNA analysis. Their state-of-the-art collection of easily reproducible methods includes all of the major techniques of DNA analysis currently used in forensic identity testing. The book covers PCR-based test systems, the now widely used STR typing systems (complete with details of both manual and automated detection systems), repeat unit mapping (MVR), direct-phase minisequencing, capillary electrophoresis, and direct blotting. Also fully discussed are the recovery of DNA from a wide range of sample types (blood, semen, skeletal remains, and saliva), species testing, sex determination, and mitochondrial DNA testing. Forensic DNA Profiling Protocols captures and makes practical for all laboratories the whole array of new technologies and techniques that have revolutionized forensic science. The readily reproducible methods elucidated here represent the state-of-the-art for those scientists who want to introduce, establish, and perfect DNA identification techniques in their laboratories.

Analytical Molecular Biology

Author: Ginny C. Saunders
Publisher: Royal Society of Chemistry
ISBN: 9780854044726
Size: 11.43 MB
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DNA technology has revolutionized molecular biology, with far-reaching implications in health care, pharmaceuticals, agriculture, and forensics. This book, produced under the VAM (Valid Analytical Measurement) initiative, addresses the applicability, reliability and validation of the many methods employed. Since analytical molecular biology has typically developed in the academic and medical research environments, guidelines are also provided to ease the transition of cutting-edge techniques from the research environment to the laboratory. 27 illus.

Forensic Analysis Of Biological Evidence

Author: J. Thomas McClintock
Publisher: CRC Press
ISBN: 1466504560
Size: 35.73 MB
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A powerful tool in the identification of individuals, DNA typing has revolutionized criminal and paternity investigations. Widespread analysis is now conducted by public and private laboratories in the United States and abroad. Focusing on the basic techniques used in forensic DNA laboratories, Forensic Analysis of Biological Evidence: A Laboratory Guide for Serological and DNA Typing introduces readers to the science of serological analysis and DNA typing methods and provides a thorough background of the molecular techniques used to determine an individual’s identity or parental lineage. Originally published as Forensic DNA Analysis: A Laboratory Manual, this revised work offers updated exercises and protocols for all kinds of DNA and serological analyses with delineated objectives, step-by-step procedures, and required laboratory supplies. Each exercise in this manual: Provides an overview of forensic DNA analysis Explains the sources or types of biological material used in a particular DNA analysis Supplies the background principles and practical methodology for specific serological analysis and DNA typing techniques Simulates human forensic testing and can also be used to simulate a wide range of applications for genetic analysis The book contains an extensive glossary to make readers familiar with terminology used in the forensic analysis of biological evidence, as well as basic terms used in molecular biology. Those who master the material in this volume will understand the methodology of the investigation in DNA typing, develop an understanding of the scientific principles involved in serology and DNA analysis, and succeed in analyzing and interpreting the data generated in each exercise with clarity and confidence.

Fundamentals Of Forensic Dna Typing

Author: John M. Butler
Publisher: Academic Press
ISBN: 9780080961767
Size: 27.20 MB
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Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Forensic Science

Author: Jay A. Siegel
Publisher: CRC Press
ISBN: 9780849346316
Size: 32.33 MB
Format: PDF, Docs
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Forensic Science: The Basics explains every aspects of crime scene investigation, moving from basic areas of criminalistics and beyond to pathology, anthropology, and engineering. It also explores new and emerging areas such as forensic entomology. With no previous knowledge of either science or law required, information is self-contained and conveyed at the lowest possible non-scientific level, making this text suitable for both lower level academic adoptions as well as for a general audience. It also offers a complete package of ancillary material for instructors. Comprehensive and Up-to-Date • Covers DNA, drugs, firearms, fingerprints, and trace evidence • Includes cutting-edge material on spectroscopy, chromatography, microscopy, odontology, and entomology • Demonstrates the practical application of modern chemistry, biology, and other laboratory sciences Each chapter: • Opens with learning objectives, a chapter outline, and an introduction • Closes with a summary and review questions for self-testing • Contains real-life examples, many from the author’s own experience Build an exceptional classroom experience with this dynamic resource! • More than 200 full color nongraphic illustrations • Countless figures, tables, and charts • A wealth of supporting material including lecture slides and test questions available on www.classwire.com • Real case studies to demonstrate forensic concepts in action • Suggested student projects to reinforce learning Appropriate for High School and University Students • Written in the lucid and concise style of a master teacher • Fully explains the scientific basics required • Omits potentially traumatic photographs and subject matter About the Author Eminently qualified to create this work, Jay Siegel is both a practicing forensic expert and a master instructor. He has worked for the Virginia Bureau of Forensic Sciences and published extensively in the field. He continues to be called upon as an expert witness, having testified over 200 times in state, federal, and military courts across the country. With nearly thirty years of teaching experience, he is highly active in curriculum development for forensic science classes taught at all levels, from junior high through graduate school. He is currently director of the Forensic and Investigative Sciences Program at Purdue University in Indiana. In February of 2009, Mr. Siegel received the "Distinguished Fellow" award from the American Academy of Forensic Sciences at its annual meeting. This is the highest honor that the Academy bestows upon a fellow. In addition, George Washington University has selected Mr. Siegel for the 2008-2009 "Distinguished Alumni Scholar." This award, the highest that the University bestows upon its alumni, is designated for those who have made truly outstanding contributions to the knowledge base of their disciplines. For Instructors Only: Develop and Customize Your Curriculum Draw from hundreds of PowerPoint® slides and illustrations to supplement your lectures Organize your class with Dr. Siegel’s helpful outlines and learning objectives Review answers to end-of-chapter questions Build exams for different levels from a giant test bank of problems This book also works in conjunction with Forensic Science Laboratory Manual and Workbook, Revised Edition. All ancillary material will be available in convenient website format at www.classwire.com. Upon request, photographs, lecture slides, and a test bank are also available to instructors on CD.

Genetic Variation

Author: Michael P. Weiner
Publisher: CSHL Press
ISBN: 0879697806
Size: 54.54 MB
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Genetic Variation: A Laboratory Manualis the first compendium of protocols specifically geared towards genetic variation studies, and includes thorough discussions on their applications for human and model organism studies. Intended for graduate students and professional scientists in clinical and research settings, it covers the complete spectrum of genetic variation—from SNPs and microsatellites to more complex DNA alterations, including copy number variation. Written and edited by leading scientists in the field, the early sections of the manual are devoted to study design and generating genotype data, the use of resources such as HapMap and dbSNP, as well as experimental, statistical, and bioinformatic approaches for analyzing the data. The final sections include descriptions of genetic variation in model organisms and discussions of recent insights into human genetic ancestry, forensics, and human variation.