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Foundations Of Clinical Research

Author: Leslie Gross Portney
Publisher: F A Davis Company
ISBN: 9780803646575
Size: 78.19 MB
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Draw upon the foundations necessary for finding and interpreting research evidence across all healthcare professions. Revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, you'll find a growing emphasis on evidence-based practice (EBP) as well as new vocabulary that is being integrated into research and practice across disciplines.

Foundations Of Clinical Research

Author: Leslie G Portney
Publisher: F.A. Davis
ISBN: 0803647344
Size: 11.41 MB
Format: PDF
View: 6619
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Draw upon the foundations necessary for finding and interpreting research evidence across all healthcare professions. Revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, you’ll find a growing emphasis on evidence-based practice (EBP) as well as new vocabulary that is being integrated into research and practice across disciplines.

Foundations Of Clinical Research

Author: Leslie Gross Portney
Publisher: Prentice Hall
ISBN: 9780131716407
Size: 76.76 MB
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Foundations of Clinical Research: Applications to Practice, 3/e provides the foundations that are necessary for finding and interpreting research evidence across all healthcare professions. This book has been revised to reflect the most current changes in the field of clinical research in rehabilitation and medicine, including the growing emphasis on evidence-based practice (EBP) that has become central to all of health care and the new vocabulary that is being integrated into research and practice across disciplines. There is also a new chapter on systematic reviews and meta-analysis as well as expanded content related to clinical decision making, including likelihood ratios, pretest and posttest probabilities, minimally important change and number needed to treat.

Foundations Of Clinical Research

Author: Leslie Gross Portney
Publisher:
ISBN: 9781292020365
Size: 48.18 MB
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Foundations of Clinical Research: Applications to Practice, 3/e serves as a comprehensive reference for a variety of research situations. This edition reflects the contemporary focus on evidence-based practice in health care, and the essential concepts for understanding analysis and research design. Expanded topics include measures of diagnostic accuracy, statistical estimates of validity and reliability, systematic reviews and meta-analysis, search strategies and critical appraisal of literature for clinical decision making and development of research. Written for those in the health professions, including physical therapy, occupational therapy, speech therapy, nursing, and exercise physiology, this text will be useful to developing clinicians, practitioners, graduate students and researchers.

Critical Thinking In Clinical Research

Author: Felipe Fregni
Publisher: Oxford University Press
ISBN: 0199324492
Size: 14.89 MB
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One of the most crucial skills a clinician, scientist, or student can learn is to create, conduct, and interpret the conclusions of a clinical study. Critical Thinking in Clinical Research teaches these fundamentals in four distinct sections, called "units": the first unit focuses on issues surrounding the design of a study such as population, question selection, randomization, and blinding; Unit 2 presents statistical methods such as analyzing data collected, how to present and discuss the data concisely; the third unit covers practical aspects such as methodology, organizational considerations, principles of trial conduct and reporting; and the final unit delves into study designs, providing the advantages and drawbacks of each design style. Each chapter begins with a short introduction, followed by a hypothetical case that challenges the reader to make decisions, to consider pros and cons of specific approaches, and to evaluate options based on specific conditions. Knowing how to critically read and understand scientific papers and to collect, analyze, and interpret research data, which they in turn can then present in their own scientific manuscript makes this book the perfect resource for anyone looking to contribute to the wealth of scientific and medical inquiry.

Principles And Practice Of Clinical Research

Author: John I. Gallin
Publisher: Academic Press
ISBN: 0128499044
Size: 19.19 MB
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Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research. New to this edition of this highly regarded reference, authors have focused on examples that broadly reflect clinical research on a global scale while including a discussion of international regulations, studies, and implications. In addition to key topics such as bioethics, clinical outcome data, cultural diversity, protocol guidelines, and “omic platforms, this edition contains new chapters devoted to electronic health records and information resources for clinical researchers, as well as the many opportunities associated with big data. Covering a vast number of topics and practical advice for both novice and advanced clinical investigators, this book is a highly relevant and essential resource for all those involved in conducting research. Features input from experts in the field dedicated to translating scientific research from bench to bedside and back Provides expanded coverage of global clinical research Contains hands-on, practical suggestions, illustrations, and examples throughout Includes new chapters on the international regulation of drugs and biologics, the emergence of the important role of comparative effectiveness research and how to identify clinical risks and manage patient safety in a clinical research setting

Clinical Epidemiology

Author: R. Brian Haynes
Publisher: Lippincott Williams & Wilkins
ISBN: 1451178794
Size: 77.89 MB
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The Third Edition of this popular text focuses on clinical-practice research methods. It is written by clinicians with experience in generating and answering researchable questions about real-world clinical practice and health care—the prevention, treatment, diagnosis, prognosis, and causes of diseases, the measurement of quality of life, and the effects of innovations in health services. The book has a problem-oriented and protocol-based approach and is written at an introductory level, emphasizing key principles and their applications. A bound-in CD-ROM contains the full text of the book to help the reader locate needed information.

Understanding Clinical Research

Author: Renato D. Lopes
Publisher: McGraw Hill Professional
ISBN: 0071792651
Size: 77.31 MB
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A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials

Foundations And Applications Of Medical Biochemistry In Clinical Practice

Author: John Neustadt Nd
Publisher: iUniverse
ISBN: 9781440125348
Size: 80.31 MB
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The culmination of more than ten years of research by the authors, this book describes for the first time ever the scientific basis and clinical applications of medical biochemistry, a fundamental paradigm shift in medicine. This paradigm shift is so revolutionary that it has been called the Neustadt-Pieczenik Paradigm, which is the fusion and clinical applications of biochemistry, thermodynamics, physiology, fractal enzymology, nutritional medicine and laboratory testing to identify and correct the underlying causes of many diseases that are considered genetic in nature (eg, Phenylketonuria) and those that are not considered genetic (eg, mature onset asthma, depression, fatigue). In this new medicine, doctors must reject the failed, purely symptomatic treatments they learned in medical school and focus on learning and treating the underlying biochemical causes of disease. From the first documented clinical observations of biochemical individuality in the early 1900s to the development of sophisticated biochemical tests, the authors provide a detailed and stunning analysis of a new medical model to help millions and cure our ailing healthcare system. They uniquely contrast the conventional medical approach with the functional biochemical approach through extensive case studies on depression, arthritis, migraine headaches, seizures, rashes and more. This book is a must-read for physicians, medical students, nutritionists, and anyone looking to take charge of their health.