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Fundamentals Of Modern Bioprocessing

Author: Sarfaraz K. Niazi
Publisher: CRC Press
ISBN: 1466585749
Size: 65.39 MB
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Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.

Cell Culture Technology For Pharmaceutical And Cell Based Therapies

Author: Sadettin Ozturk
Publisher: CRC Press
ISBN: 9780849351068
Size: 41.40 MB
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Edited by two of the most distinguished pioneers in genetic manipulation and bioprocess technology, this bestselling reference presents a comprehensive overview of current cell culture technology used in the pharmaceutical industry. Contributions from several leading researchers showcase the importance of gene discovery and genomic technology development in the production of biotechnology products, tissue engineering, and cell-based therapies. Offering detailed guidance, they cover the steps leading up to the creation of viable therapies including host cell selection, cloning and gene amplification, bioreactor design and operation, protein purification, optimization, scale-up, and facility design.

Bioprocess Engineering

Author: Michael L. Shuler
Publisher:
ISBN:
Size: 58.81 MB
Format: PDF
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Showing readers how to apply basic engineering skills to modern problems in bioprocessing, this introductory reference covers biological - biochemistry, microbiology, molecular biology - fundamentals and engineering principles of biochemical/bioprocess engineering. Aimed at beginners in the field, it offers a unique, comprehensive overview of the field with illustrative examples and problems.

Bioprocess Engineering For A Green Environment

Author: V. Sivasubramanian
Publisher: CRC Press
ISBN: 1351867865
Size: 40.50 MB
Format: PDF, ePub
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This book deals with bioprocess engineering, which encompasses the design and development of equipment and processes for the manufacturing of products such as food, pharmaceuticals, chemicals, polymers and paper from biological materials. It also deals with studying various biotechnological processes used in industries for large scale production of biological products, for the optimization of yield. This work also incorporates significant treatment on biocatalysts and their applications in food industry, bioplastics production, conversion of agro waste and the importance of biotechnology in bioprocessing. This is coupled with pertinent information related to environmental contaminants.

Bioprocess Engineering

Author: Shijie Liu
Publisher: Elsevier
ISBN: 0444637931
Size: 34.46 MB
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Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems. Includes the mechanistic description of biotransformations and chemical transformations Provides quantitative descriptions of bioprocesses Contains extensive illustrative drawings, which make the understanding of the subject easy Includes bioprocess kinetics and reactor analysis Contains examples of the various process parameters, their significance, and their specific practical use Incorporates sustainability concepts into the various bioprocesses

Bioprocessing For Value Added Products From Renewable Resources

Author: Shang-Tian Yang
Publisher: Elsevier
ISBN: 9780080466712
Size: 26.19 MB
Format: PDF, ePub
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Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry

International Conference On Harmonisation Ich Quality Guidelines

Author: Mindy J. Allport-Settle
Publisher: Pharmalogika
ISBN: 9780982147658
Size: 22.19 MB
Format: PDF, Docs
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ICH Quality Guidelines: * Overview and Orientation * Introduction * Part I: Stability [Q1A(R2), Q1B, Q1C, Q1D, Q1E] * Part II: Analytical Validation [Q2(R1)] * Part III: Impurities [Q3A(R2), Q3B(R2), Q3C(R4)] * Part IV: Pharmacopoeias (List Overview) * Part V: Quality of Biotechnological Products [Q5A(R1), Q5B, Q5C, Q5D, Q5E] * Part VI: Specifications [Q6A, Q6B] * Part VII: Good Manufacturing Practice [Q7] * Part VIII: Pharmaceutical Development [Q8(R2)] * Part IX: Quality Risk Management [Q9] * Part X: Pharmaceutical Quality System [Q10] Reference Tools * Part XI: Questions and Answers for Q8/9/10 Quality Guidance Documents * Part XII: Combined Glossary and Index for all Quality Guidance Documents

Biotechnology Fundamentals

Author: Firdos Alam Khan
Publisher: CRC Press
ISBN: 1439820090
Size: 24.47 MB
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The focus of Biotechnology Fundamentals is to educate readers on both classical and modern aspects of biotechnology and to expose them to a range of topics, from basic information to complex technicalities. Other books cover subjects individually, but this text offers a rare topical combination of coverage, using numerous helpful illustrations to explore the information that students and researchers need to intelligently shape their careers. Keeping pace with the rapid advancement of the field, topics covered include: How biotechnology products are produced Differences between scientific research conducted in universities and industry Which areas of biotechnology offer the best and most challenging career opportunities Key laboratory techniques and protocols employed in the field The contents of this book are derived from discussions between teachers and undergraduate students and designed to address the concepts and methods thought useful by both sides. Starting with the fundamentals of biotechnology, coverage includes definitions, historical perspectives, timelines, and major discoveries, in addition to products, research and development, career prospects, ethical issues, and future trends. The author explains that even before it had been classified as its own field, biotechnology was already being applied in plant breeding, in vitro fertilization, alcohol fermentation, and other areas. He then delves into new developments in areas including stem cell research, cloning, biofuels, transgenic plants, genetically modified food/crops, pharmacogenomics, and nanobiotechnology. Incorporating extensive pedagogy into the content, this book provides plenty of examples, end-of-chapter problems, case studies, and lab tutorials to help reinforce understanding.

Chemical And Bioprocess Engineering

Author: Ricardo Simpson
Publisher: Springer Science & Business Media
ISBN: 1461491266
Size: 64.47 MB
Format: PDF, ePub, Mobi
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The goal of this textbook is to provide first-year engineering students with a firm grounding in the fundamentals of chemical and bioprocess engineering. However, instead of being a general overview of the two topics, Fundamentals of Chemical and Bioprocess Engineering will identify and focus on specific areas in which attaining a solid competency is desired. This strategy is the direct result of studies showing that broad-based courses at the freshman level often leave students grappling with a lot of material, which results in a low rate of retention. Specifically, strong emphasis will be placed on the topic of material balances, with the intent that students exiting a course based upon this textbook will be significantly higher on Bloom’s Taxonomy (knowledge, comprehension, application, analysis and synthesis, evaluation, creation) relating to material balances. In addition, this book also provides students with a highly developed ability to analyze problems from the material balances perspective, which leaves them with important skills for the future. The textbook consists of numerous exercises and their solutions. Problems are classified by their level of difficulty. Each chapter has references and selected web pages to vividly illustrate each example. In addition, to engage students and increase their comprehension and rate of retention, many examples involve real-world situations.