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Game Theoretical Models In Biology

Author: Mark Broom
Publisher: CRC Press
ISBN: 1439853215
Size: 18.63 MB
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Covering the major topics of evolutionary game theory, Game-Theoretical Models in Biology presents both abstract and practical mathematical models of real biological situations. It discusses the static aspects of game theory in a mathematically rigorous way that is appealing to mathematicians. In addition, the authors explore many applications of game theory to biology, making the text useful to biologists as well. The book describes a wide range of topics in evolutionary games, including matrix games, replicator dynamics, the hawk-dove game, and the prisoner’s dilemma. It covers the evolutionarily stable strategy, a key concept in biological games, and offers in-depth details of the mathematical models. Most chapters illustrate how to use MATLAB® to solve various games. Important biological phenomena, such as the sex ratio of so many species being close to a half, the evolution of cooperative behavior, and the existence of adornments (for example, the peacock’s tail), have been explained using ideas underpinned by game theoretical modeling. Suitable for readers studying and working at the interface of mathematics and the life sciences, this book shows how evolutionary game theory is used in the modeling of these diverse biological phenomena.

Kompendium Systembiologie

Author: Andreas Kremling
Publisher: Springer-Verlag
ISBN: 3834886076
Size: 13.62 MB
Format: PDF, Kindle
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Das Buch beschreibt die Grundlagen der mathematischen Modellierung zellulärer Systeme. Nach einer Klassifikation von Modellen wird schwerpunktmäßig auf deterministische Modelle eingegangen und für alle relevanten zellulären Prozesse entsprechende Gleichungen angegeben. Anschließend werden eine Reihe von Verfahren zur Modellanalyse vorgestellt. Etwas kürzer werden Verfahren zum Reverse Engineering und zur Analyse von Netzwerkgraphen abgehandelt. Am Ende werden noch Verfahren der Parameteridentifikation besprochen.

A Systems Theoretic Approach To Systems And Synthetic Biology I Models And System Characterizations

Author: Vishwesh V. Kulkarni
Publisher: Springer
ISBN: 9401790418
Size: 21.31 MB
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The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems. More recently, the field of synthetic biology, i.e., de novo engineering of biological systems, has emerged. Scientists from various fields are focusing on how to render this engineering process more predictable, reliable, scalable, affordable, and easy. Systems and control theory is a branch of engineering and applied sciences that rigorously deals with the complexities and uncertainties of interconnected systems with the objective of characterising fundamental systemic properties such as stability, robustness, communication capacity, and other performance metrics. Systems and control theory also strives to offer concepts and methods that facilitate the design of systems with rigorous guarantees on these properties. Over the last 100 years, it has made stellar theoretical and technological contributions in diverse fields such as aerospace, telecommunication, storage, automotive, power systems, and others. Can it have, or evolve to have, a similar impact in biology? The chapters in this book demonstrate that, indeed, systems and control theoretic concepts and techniques can have a significant impact in systems and synthetic biology. Volume I provides a panoramic view that illustrates the potential of such mathematical methods in systems and synthetic biology. Recent advances in systems and synthetic biology have clearly demonstrated the benefits of a rigorous and systematic approach rooted in the principles of systems and control theory - not only does it lead to exciting insights and discoveries but it also reduces the inordinately lengthy trial-and-error process of wet-lab experimentation, thereby facilitating significant savings in human and financial resources. In Volume I, some of the leading researchers in the field of systems and synthetic biology demonstrate how systems and control theoretic concepts and techniques can be useful, or should evolve to be useful, in order to understand how biological systems function. As the eminent computer scientist Donald Knuth put it, "biology easily has 500 years of exciting problems to work on". This edited book presents but a small fraction of those for the benefit of (1) systems and control theorists interested in molecular and cellular biology and (2) biologists interested in rigorous modelling, analysis and control of biological systems.

Dynamics Games And Science Ii

Author: Mauricio Matos Peixoto
Publisher: Springer Science & Business Media
ISBN: 9783642147883
Size: 79.20 MB
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Dynamics, Games and Science I and II are a selection of surveys and research articles written by leading researchers in mathematics. The majority of the contributions are on dynamical systems and game theory, focusing either on fundamental and theoretical developments or on applications to modeling in biology, ecomonics, engineering, finances and psychology. The papers are based on talks given at the International Conference DYNA 2008, held in honor of Mauricio Peixoto and David Rand at the University of Braga, Portugal, on September 8-12, 2008. The aim of these volumes is to present cutting-edge research in these areas to encourage graduate students and researchers in mathematics and other fields to develop them further.

Systems Evolutionary Biology

Author: Bor-Sen Chen
Publisher: Academic Press
ISBN: 0128140739
Size: 21.45 MB
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Systems Evolutionary Biology: Biological Network Evolution Theory, Stochastic Evolutionary Game Strategies, and Applications to Systems Synthetic Biology discusses the evolutionary game theory and strategies of nonlinear stochastic biological networks under random genetic variations and environmental disturbances and their application to systematic synthetic biology design. The book provides more realistic stochastic biological system models to mimic the real biological systems in evolutionary process and then introduces network evolvability, stochastic evolutionary game theory and strategy based on nonlinear stochastic networks in evolution. Readers will find remarkable, revolutionary information on genetic evolutionary biology that be applied to economics, engineering and bioscience. Explains network fitness, network evolvability and network robustness of biological networks from the systematic perspective Discusses the evolutionary noncooperative and cooperative game strategies of biological networks Offers detailed diagrams to help readers understand biological networks, their systematic behaviors and the simulational results of evolutionary biological networks Includes examples in every chapter with computational simulation to illustrate the solution procedure of evolutionary theory, strategy and results

Modeling And Simulation

Author: Hartmut Bossel
Publisher: Springer-Verlag
ISBN: 3663108228
Size: 76.39 MB
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This book is the the English Language Version of the very successful German textbook, "Modellbildung und Simulation". It provides a self-contained and complete guide to the methods and mathematical background of modeling and simulation software of dynamic systems. Furthermore, an appropriate simulation software and a collection of dynamic system models (on the accompanying disk) are highlights of the book/software-Package.Dies ist die englischsprachige Ausgabe des sehr erfolgreichen Lehrbuches "Modellbildung und Simulation". Geboten wird eine vollständige Einführung in die Methoden der Simulation dynamischer Systeme, wobei auch der notwendige mathematische Hintergrund vermittelt wird. Außerdem ist eine Simulationssoftware Bestandteil des Werkes; auf der beiliegenden Diskette befinden sich ferner 50 Beispielsysteme ("Systemzoo"), die zur spielerischen Einübung der verwendeten Verfahren hilfreich sind.