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Heart Valves

Author: Paul A. Iaizzo
Publisher: Springer Science & Business Media
ISBN: 1461461448
Size: 65.13 MB
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Cardiovascular disease is the major cause of morbidity and mortality worldwide. While the past 40 years have brought major progress in cardiac valve repair and replacement, there remain large patient populations that do not receive such therapies. This, in turn, implies a great need for future basic, applied, and clinical research and, ultimately, therapeutic developments. Heart Valves is a state-of-the-art handbook dedicated to: 1) cardiac valve anatomy, 2) models for testing and research methods; 3) clinical trials; and 4) clinical needs and applications.

Transcatheter Valve Therapies

Author: Christoph Huber
Publisher: CRC Press
ISBN: 1439810826
Size: 56.65 MB
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The landscape of cardiac surgery is changing, as is the field of interventional cardiology. The idea of accessing and replacing a failing valve through the patients vasculature has become the most rapidly expanding therapy of choice in cardiovascular disease. Transcatheter Valve Therapies chronicles the astonishing advances that have taken place in the field and prepares readers for the challenging future of cardiac valve therapies. Designed to meet the growing needs of cardiologists, cardiac surgeons, anesthetists, and general practitioners, the book covers all aspects from logistic needs to clinical outcomes. It provides a comprehensive overview of transcatheter valve therapies and the necessary understanding for a successful clinical introduction at individual institutions. Topics include: Epidemiologic considerations Aspects of balloon aortic valvuloplasty as a stand-alone procedure or as part of the transcatheter valve replacement The history of how transcatheter valve therapies were implemented into surgical practice New imaging modalities The particularities of transcatheter access Aortic root anatomy Emerging technologies and future design improvements Development steps of aortic devices and potential solutions for transcatheter tricuspid, mitral, and pulmonary valve replacement The rigorous testing requirements for endovascular medical devices Clinical results of aortic transcatheter valve therapies in easy accessible text and table formats The future of transcatheter valve therapies All topics are discussed based on the author’s own clinical and experimental experience in the field. This volume is essential for anyone involved in transcatheter valve implantation, clinicians wishing to become more involved in improving transcatheter valve therapies, and researchers engaged in building and creating new medical technologies to shape the cardiovascular landscape of the future.

Cardiac Reconstructions With Allograft Tissues

Author: Richard A. Hopkins
Publisher: Springer Science & Business Media
ISBN: 0387265155
Size: 20.26 MB
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Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition ("Cardiac Reconstructions with Allograft Valves") in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table. All surgeons performing pediatric and/or adult valve replacements and reconstructive cardiac surgeries will benefit from the described methods. Cardiothoracic residents and cardiologists will also find the text useful. It will provide the surgeon with an enhanced understanding of the biological and material properties of allografts and increased familiarity with the range of surgical techniques applicable for the use of these valves, particularly in the successful management of challenging cardiac reconstructions.>

Transcatheter Valve Repair

Author: Ziyad M. Hijazi
Publisher: CRC Press
ISBN: 9781841844725
Size: 66.34 MB
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Transcatheter Valve Repair discusses all aspects related to percutaneous and established valve repair methods. The book is divided into few major sections covering all four valves and other topics. Each section contains several chapters discussing everything related to that valve. Beginning with the pulmonary valve, since it was the first valve to be tackled in the catheterization laboratory, and then moving to the aortic, then the mitral and then finally end with the tricuspid valve. 1.5M US citizens alone have some degree of aortic valve stenosis, with half (750K) requiring aortic valve replacement. Aortic valve replacement, on the whole, is performed by surgeons, requiring bypass machines and technicians, as well as the usual operating team. The operation is expensive and occupies a considerable amount of operating room time. Mostly, the aortic valve is calcified and the usual option available to patients is valve replacement with a variety of choices, ranging from porcine valves to synthetic, for which there are many manufacturers. It should be noted that the aortic valve is the most problematic of valves. Percutaneous procedures are the answer. The bottom line is that given the growing elderly population, many more patients will require valve repair, thus increasing health care costs with not only surgical operations but also hospitalisation. Percutanous valve repair, whilst requiring a cath lab team, does not involve bypass machines nor extended hospitalisation. Like percutaneous transluminal coronary artery interventions (PTCA) has replaced coronary artery bypass grafts (once the golden standard), and now stenting having replaced PTCA and its balloons. We now see drug eluting stents replacing ordinary stents (though at a much higher cost. There will be a huge movement toward percutanous valve repair, which should presumably cut costs but also morbidity and mortality.

Biomaterials Science

Author: Buddy D. Ratner
Publisher: Academic Press
ISBN: 008087780X
Size: 29.98 MB
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The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. Over 29,000 copies sold, this is the most comprehensive coverage of principles and applications of all classes of biomaterials: "the only such text that currently covers this area comprehensively" - Materials Today Edited by four of the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and expanded, key new topics include of tissue engineering, drug delivery systems, and new clinical applications, with new teaching and learning material throughout, case studies and a downloadable image bank

Tissue Engineering And Artificial Organs

Author: Joseph D. Bronzino
Publisher: CRC Press
ISBN: 1420003879
Size: 59.55 MB
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Over the last century, medicine has come out of the "black bag" and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiology to material science and nanotechnology. Reflecting the enormous growth and change in biomedical engineering during the infancy of the 21st century, The Biomedical Engineering Handbook enters its third edition as a set of three carefully focused and conveniently organized books. Reviewing applications at the leading edge of modern biomedical engineering, Tissue Engineering and Artificial Organs explores transport phenomena, biomimetics systems, biotechnology, prostheses, artificial organs, and ethical issues. The book features approximately 90% new material in the tissue engineering section, integrates coverage of life sciences with a new section on molecular biology, and includes a new section on bionanotechnology. Prominent leaders from around the world share their expertise in their respective fields with many new and updated chapters. New technologies and methods spawned by biomedical engineering have the potential to improve the quality of life for everyone, and Tissue Engineering and Artificial Organs sheds light on the tools that will enable these advances.

Echocardiography

Author: Petros Nihoyannopoulos
Publisher: Springer Science & Business Media
ISBN: 9781848822931
Size: 60.64 MB
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As increasing emphasis is placed on evidence-based medicine and the need to a rapid and clinically effective diagnosis of cardiac disease, so echocardiography is ever-more present at the forefront of cardiology. This book represents the current knowledge in the technique of cardiology and is designed to guide the resident and fellow through the most common applications of echocardiography while touching on some of the less often seen echocardiographic diagnoses.

Follow Up After Cardiovascular Surgery Ecab

Author: O P Yadava
Publisher: Elsevier Health Sciences
ISBN: 8131231739
Size: 80.64 MB
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Follow-up of patients after surgery is of utmost importance as results of the surgery heavily depend on the treatment of patient in the follow-up period. A good follow-up and proper treatment also provides protection to the patient from various complications and recurrence of the disease. Therapeutic guidelines and algorithms for treatment of the patients after discharge from the hospitals exist for a number of cardiovascular disorders. Still, follow-up and postdischarge treatment is very often found to be inappropriate and incomplete. This results in many avoidable complications for both the patient as well as the treating clinician. This book is designed to update the readers on follow-up regimens for some of the important cardiovascular surgical procedures. Typical supportive case scenarios are included to exemplify and highlight the various points discussed. Thus it provides an excellent opportunity to widen one’s perspective in this area.

Guide To Prosthetic Cardiac Valves

Author: Dryden Morse
Publisher: Springer Science & Business Media
ISBN: 146125096X
Size: 62.60 MB
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Weare entering an especially prolific era in reporting and publishing clinical experiences with cardiac valve replacement. A voluminous litera ture on this subject is already in existence, emanating from clinicians, surgeons, bioengineers, and other scientists. Additionally, information presented at heart valve symposia in the form of bound collections reaches the shelves of the medical book stores every year. This activity reflects the dynamic state of cardiac valve technology, highlighted by the introduction each year of new valve designs that often utilize new materials. As a result, the authors recognized the need to update their book The Pacemaker and Valve Identification Guide, separating the contents into two volumes dealing with pacemakers* and cardiac valve technology. For this Guide to Prosthetic Cardiac Valves, we have gathered a group of recognized authorities in the field, all of whom have contributed in depth analysis in their areas of expertise. New material dealing with the preoperative and postoperative care ofthe heart valve patient, pathol ogy of cardiac valves, bioengineering problems of cardiac valve technol ogy, and separate chapters on valve implantation in children and ultra sonography have been added. Chapter 3, "The Radiology of Prosthetic Heart Valves," we feel will be particularly helpful to the physician in identifying a prosthetic valve and revealing the most likely complica tions. Chapter 10 is an atlas with descriptions to supply the reader with the essential features of the various prostheses when he or she is faced with a new patient bearing an implanted cardiac valve.

Learning From Nature How To Design New Implantable Biomaterials From Biomineralization Fundamentals To Biomimetic Materials And Processing Routes

Author: Rui L. Reis
Publisher: Springer Science & Business Media
ISBN: 140202648X
Size: 51.82 MB
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The development of materials for any replacement or regeneration application should be based on the thorough understanding of the structure to be substituted. This is true in many fields, but particularly exigent in substitution and regeneration medicine. The demands upon the material properties largely depend on the site of application and the function it has to restore. Ideally, a replacement material should mimic the living tissue from a mechanical, chemical, biological and functional point of view. Of course this is much easier to write down than to implement in clinical practice. Mineralized tissues such as bones, tooth and shells have attracted, in the last few years, considerable interest as natural anisotropic composite structures with adequate mechanical properties. In fact, Nature is and will continue to be the best materials scientist ever. Who better than nature can design complex structures and control the intricate phenomena (processing routes) that lead to the final shape and structure (from the macro to the nano level) of living creatures? Who can combine biological and physico-chemical mechanisms in such a way that can build ideal structure-properties relationships? Who, else than Nature, can really design smart structural components that respond in-situ to exterior stimulus, being able of adapting constantly their microstructure and correspondent properties? In the described philosophy line, mineralized tissues and biomineralization processes are ideal examples to learn-from for the materials scientist of the future.