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Heat Shock Proteins And Whole Body Adaptation To Extreme Environments

Author: Michael B. Evgen'ev
Publisher: Springer
ISBN: 9401792356
Size: 80.96 MB
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For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.

Occupational Safety And Hygiene Vi

Author: Pedro M. Arezes
Publisher: CRC Press
ISBN: 1351008862
Size: 64.62 MB
Format: PDF, ePub
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Occupational Safety and Hygiene VI collects recent papers of selected authors from 21 countries in the domain of occupational safety and hygiene (OSH). The contributions cover a wide range of topics, including: - Occupational safety - Risk assessment - Safety management - Ergonomics - Management systems - Environmental ergonomics - Physical environment - Construction safety, and - Human factors Occupational Safety and Hygiene VI represents the state-of-the-art on the above mentioned domains, and is based on research carried out at universities and other research institutions. Some contributions focus more on practical case studies developed by OSH practitioners within their own companies. Hence, the book provides practical tools and approaches currently used by OHS practitioners in a global context.

Hsp70 In Human Diseases And Disorders

Author: Alexzander A. A. Asea
Publisher: Springer
ISBN: 3319895516
Size: 74.80 MB
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The book HSP70 in Human Diseases and Disorders provides the most comprehensive review on contemporary knowledge on the role of HSP70 family - one of the most studied HSP - in human diseases and disorders. Using an integrative approach to expand our current understanding of HSP70 functions, the contributors provide a synopsis of novel mechanisms by which HSP70 is involved in the regulation of human diseases and disorders. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for medical students and residents, clinical and basic science researchers, postdoctoral fellows and graduate students in the fields of Medicine, Physiology, Clinical Trials, Biotechnology, Molecular Medicine and Pathology.

Heat Shock Proteins And Whole Body Physiology

Author: Alexzander A. A. Asea
Publisher: Springer Science & Business Media
ISBN: 9789048133819
Size: 45.77 MB
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Heat Shock Proteins and Whole Body Physiology is an exciting new book in the Heat Shock Proteins series which provides the most up-to-date review on novel mechanisms insights into the important role played by heat shock proteins in human physiology. Written by leaders in the field of heat shock protein exercise physiology, neuroscience and aging, the chapters systematically and in a step wise fashion takes the reader through the fascinating mechanisms by which heat shock proteins modulate human disease and pathophysiology and provides answers as to its biological significance to the host. Section I, introduces the readers to the role played by heat shock proteins in various diseases and disorders (Heat Shock Proteins and Disease). Section II, addresses the role heat shock proteins play in psychological disorders including post traumatic stress disorders and learning (Heat Shock Proteins and Psychological Stress). Section III, present a detailed review of the role played by heat shock proteins in exercise physiology (Heat Shock Proteins and Exercise Physiology). This book is a must read for heat shock protein researchers, graduate and postgraduate fellows in the field of Medicine in general and specialities in Excersie Physiology, Neuroscience, Immunology, Aging and Pathology.

Wilderness Medicine E Book

Author: Paul S. Auerbach
Publisher: Elsevier Health Sciences
ISBN: 1455733563
Size: 77.63 MB
Format: PDF, ePub, Mobi
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Quickly and decisively manage any medical emergency you encounter in the great outdoors with Wilderness Medicine! World-renowned authority and author, Dr. Paul Auerbach, and a team of experts offer proven, practical, visual guidance for effectively diagnosing and treating the full range of emergencies and health problems encountered in situations where time and resources are scarce. Every day, more and more people are venturing into the wilderness and extreme environments, or are victims of horrific natural disasters...and many are unprepared for the dangers and aftermath that come with these episodes. Whether these victims are stranded on mountaintops, lost in the desert, injured on a remote bike path, or ill far out at sea, this indispensable resource--now with online access at www.expertconsult.com for greater accessibility and portability-- equips rescuers and health care professionals to effectively address and prevent injury and illness in the wilderness! This textbook is widely referred to as "The Bible of Wilderness Medicine." Be able to practice emergency medicine outside of the traditional hospital/clinical setting whether you are in remote environments, underdeveloped but highly populated areas, or disaster areas, are part of search and rescue operations, or dealing with casualties from episodes of extreme sports and active lifestyle activities. Face any medical challenge in the wilderness with expert guidance: Dr. Auerbach is a noted author and the world's leading authority on wilderness medicine. He is a founder and Past President of the Wilderness Medical Society, consultant to the Divers Alert Network and many other agencies and organizations, and a member of the National Medical Committee for the National Ski Patrol System. Handle everything from frostbite to infection by marine microbes, not to mention other diverse injuries, bites, stings, poisonous plant exposures, animal attacks, and natural disasters. Grasp the essential aspects of search and rescue. Respond quickly and effectively by improvising with available materials. Improve your competency and readiness with the latest guidance on volcanic eruptions, extreme sports, splints and slings, wilderness cardiology, living off the land, aerospace medicine, mental health in the wilderness, tactical combat casualty care, and much more. Meet the needs and special considerations of specific patient populations such as children, women, elders, persons with chronic medical conditions, and the disabled. Make smart decisions about gear, navigation, nutrition, and survival. Be prepared for everything with expanded coverage on topics such as high altitude, cold water immersion, and poisonous and venomous plants and animals. Get the skills you need now with new information on global humanitarian relief and expedition medicine, plus expanded coverage of injury prevention and environmental preservation. Get guidance on the go with fully searchable online text, plus bonus images, tables and video clips - all available on ExpertConsult.com.

Understanding Ageing

Author: Robin Holliday
Publisher: Cambridge University Press
ISBN: 9780521478021
Size: 42.34 MB
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This book presents a completely novel approach to understanding aging: it explains both why aging exists in animals and reviews our current understanding of it at the biological level. Dr. Holliday argues that much research needs to be done on the cellular and molecular aspects of aging if the origin of age-related diseases is to be understood. In making this argument, the author draws on material from a wide range of disciplines, including extensive biomedical information about age-related disease in humans. This thought-provoking book will appeal to all students and researchers who are interested in aging, whether they are working in the clinical or basic research sphere.

An Introduction To Ecological Genomics

Author: Nico M. van Straalen
Publisher: OUP Oxford
ISBN: 0191624616
Size: 36.74 MB
Format: PDF, ePub
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The genomics revolution has expanded from its origins in molecular biology to impact upon every discipline in the life sciences, including ecology. Several lines of ecological research can now be profitably addressed using genomics technology, including issues of nutrient cycling, population structure, life-history variation, trophic interaction, stress responses, and adaptation to environmental change. This new edition addresses a series of fundamental ecological questions: the relationship between community structure and ecological function in ecosystems; how variation in life-history patterns among species can be explained from interaction between the genome and the environment; the molecular responses to changing and toxic environmental conditions; adaptive phenotypes and their relationship to genetic variation. Each of these questions is evaluated in the light of recent advances in genomics research, paying particular attention to data obtained from sequencing and screening of environmental genomes (metagenomics), microarray-based transcription profiling, gene expression directed by signal-transduction pathways, and the analysis of genomic polymorphisms. The chapters covering these key areas are preceded by discussions of genomics methodology (including an overview of next-generation sequencing technologies) and comparative genomics, and the book concludes with a chapter on integrative approaches such as ecological control analysis. The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models. An Introduction to Ecological Genomics incorporates a balance of plant, animal, and microbial examples, and continues to define the new and exciting field of ecological genomics.

The Biology Of Human Survival

Author: Claude A. Piantadosi
Publisher: Oxford University Press
ISBN: 9780199748075
Size: 44.86 MB
Format: PDF, Docs
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The range of environments in which people can survive is extensive, yet most of the natural world cannot support human life. The Biology of Human Survival identifies the key determinants of life or death in extreme environments from a physiologist's perspective, integrating modern concepts of stress, tolerance, and adaptation into explanations of life under Nature's most austere conditions. The book examines how individuals survive when faced with extremes of immersion, heat, cold or altitude, emphasizing the body's recognition of stress and the brain's role in optimizing physiological function in order to provide time to escape or to adapt. In illustrating how human biology adapts to extremes, the book also explains how we learn to cope by blending behavior and biology, first by trial and error, then by rigorous scientific observation, and finally by technological innovation. The book describes life-support technology and how it enables humans to enter once unendurable realm, from the depths of the ocean to the upper reaches of the atmosphere and beyond. Finally, it explores the role that advanced technology might play in special environments of the future, such as long journeys into space.

Llama And Alpaca Care E Book

Author: Chris Cebra
Publisher: Elsevier Health Sciences
ISBN: 032324291X
Size: 37.79 MB
Format: PDF, ePub
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Designed for the mixed practice large animal veterinarian, veterinary students, and camelid caretakers alike, Llama and Alpaca Care covers all major body systems, herd health, physical examination, nutrition, reproduction, surgery, anesthesia, and multisystem diseases of llamas and alpacas. Written by world-renowned camelid specialists and experts in the field, this comprehensive and uniquely global text offers quick access to the most current knowledge in this area. With coverage ranging from basic maintenance such as restraint and handling to more complex topics including anesthesia and surgery, this text provides the full range of knowledge required for the management of llamas and alpacas. "..an essential text for anyone working with South American camelids." Reviewed by Claire E. Whitehead on behalf of Veterinary Record, July 2015 Over 500 full-color images provide detailed, highly illustrated coverage of all major body systems, physical examination, nutrition, anesthesia, fluid therapy, multisystem diseases, and surgical disorders. World-renowned camelid experts and specialists in the field each bring a specific area of expertise for a uniquely global text. Comprehensive herd health content includes handling techniques, vaccinations, biosecurity, and protecting the herd from predators. Coverage of anesthesia and analgesia includes the latest information on pharmacokinetics of anesthetic drugs, chemical restraint, injectable and inhalation anesthesia, neuroanesthesia, and pain management. Reproduction section contains information on breeding management, lactation, infertility, and embryo transfer. Nutrition information offers detailed nutritional requirements and discusses feeding management systems and feeding behavior.