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Hematopathology

Author: Faramarz Naeim
Publisher: Academic Press
ISBN: 9780080919485
Size: 36.94 MB
Format: PDF, ePub
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This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues. * Emphasizes the immunophenotypic features, cytogenetic studies, and diagnostic molecular aspects of hematology * Features hundreds of images, charts and tables for the identification of hematologic disorders not only based on histopathologic features, but also with the use of advanced accessory techniques.

Atlas Of Hematopathology

Author: Faramarz Naeim
Publisher: Academic Press
ISBN: 0128098449
Size: 77.84 MB
Format: PDF, ePub
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Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches, Second Edition, will appeal to both a wide range of people undergoing training in a variety of medical fields and practicing non-hematopathologists. For clinicians, fellows and residents, correct diagnosis (and therefore correct treatment) of diseases depends on a strong understanding of the molecular basis for the disease, making this book a crucial resource. This atlas contains hundreds of high-quality color images that mirror the findings that fellows and clinicians encounter in practice. In addition, it provides information in a quick, simple and user-friendly manner, attracting both those in training and non- experts. Residents, fellows, practicing clinicians, and researchers in pathology, hematology and hematology/oncology will find this a useful resource. Covers both non-neoplastic hematopathology and neoplastic hematopathology in all organs and tissues Demonstrates results of important complementary diagnostic tests, such as immunophenotyping (immunohistochemical stains and flow cytometry), karyotyping, FISH and DNA/molecular studies Provides tables to summarize the most important clinicopathological features Saves clinicians and researchers time in quickly accessing the very latest details on the diverse clinical and scientific aspects of hematopathology

Atlas Of Differential Diagnosis In Neoplastic Hematopathology Third Edition

Author: Wojciech Gorczyca
Publisher: CRC Press
ISBN: 1482212250
Size: 77.89 MB
Format: PDF, Docs
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Management of tumor patients now relies on new individualized approaches to treatment, requiring extensive knowledge of the molecular makeup of tumors. Updated and expanded, the third edition of Atlas of Differential Diagnosis in Neoplastic Hematopathology examines not only the differential diagnosis but also the detailed morphologic, immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid malignancies. Featuring a new structure and including new chapters, the third edition updates all content and presents considerable expansion on many topics, including: Metaphase cytogenetic and FISH Flow cytometry (overview and detailed analysis of specific tumors) Acute myeloid leukemia and new classification schemes MDS, AML, and B- and T-cell lymphoproliferations Abnormal patterns in the lymph node and bone marrow with detail differential diagnosis based on histologic features and cellular composition Detailed differential diagnosis based on the expression of broad list of antigenic markers (flow cytometry and immunohistochemistry) Extranodal lymphomas Diagnosis of MDS and myeloproliferative neoplasm and their differential diagnosis based on the morphologic, flow cytometric, and chromosomal features The book also provides expanded differential diagnosis of the most common as well as most difficult and rare entities, including morphologic, immunophenotypic, and karyotypic/molecular features. This edition includes updated algorithms for most common diagnoses as well as several new algorithms. The majority of figures have been revised and are in full color.

Atlas Of Drosophila Morphology

Author: Sylwester Chyb
Publisher: Academic Press
ISBN: 0123846897
Size: 11.25 MB
Format: PDF, Mobi
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The Atlas of Drosophila Morphology: Wild-type and Classical Mutants is the guide every Drosophila researcher wished they had when first learning genetic markers, and the tool they wish they had now as a handy reference in their lab research. Previously, scientists had only poor-quality images or sketches to work with, and then scattered resources online - but no single visual resource quickly at their fingertips when explaining markers to new members of the lab, or selecting flies to do their genetic crosses, or hybrids. This alphabetized guide to Drosophila genetic markers lays flat in the lab for easy referencing. It contains high-resolution images of flies and the appropriate marker on the left side of each page and helpful information for the marker on the facing page, such as symbol, gene name, synonyms, chromosome location, brief informative description of the morphology, and comments on marker reliability. A companion website with updated information, useful links, and additional data provided by the authors complements this extremely valuable resource. Provides an opening chapter with a well-illustrated introduction to Drosophila morphology Features high-resolution illustrations, including those of the most common markers used by Drosophila researchers Contains brief, practical descriptions and tips for deciphering the phenotype Includes material relevant for beginners and the most experienced fly pushers

Machine Learning

Author: Marco Gori
Publisher: Morgan Kaufmann
ISBN: 0081006705
Size: 71.46 MB
Format: PDF
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Machine Learning: A Constraint-Based Approach provides readers with a refreshing look at the basic models and algorithms of machine learning, with an emphasis on current topics of interest that includes neural networks and kernel machines. The book presents the information in a truly unified manner that is based on the notion of learning from environmental constraints. While regarding symbolic knowledge bases as a collection of constraints, the book draws a path towards a deep integration with machine learning that relies on the idea of adopting multivalued logic formalisms, like in fuzzy systems. A special attention is reserved to deep learning, which nicely fits the constrained- based approach followed in this book. This book presents a simpler unified notion of regularization, which is strictly connected with the parsimony principle, and includes many solved exercises that are classified according to the Donald Knuth ranking of difficulty, which essentially consists of a mix of warm-up exercises that lead to deeper research problems. A software simulator is also included. Presents fundamental machine learning concepts, such as neural networks and kernel machines in a unified manner Provides in-depth coverage of unsupervised and semi-supervised learning Includes a software simulator for kernel machines and learning from constraints that also includes exercises to facilitate learning Contains 250 solved examples and exercises chosen particularly for their progression of difficulty from simple to complex

Diagnostic Pediatric Hematopathology

Author: Maria A. Proytcheva
Publisher: Cambridge University Press
ISBN: 0521881609
Size: 80.12 MB
Format: PDF
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An accurate and up-to-date guide to the diagnosis of benign and malignant hematologic disorders of childhood, this is an excellent reference to ensure accurate diagnoses when evaluating peripheral blood, bone marrow, and lymph node disease. It will be a valuable tool in the practice of pathologists, pediatric pathologists, and hematopathologists.

Atlas Of Hematologic Neoplasms

Author: Tsieh Sun
Publisher: Springer Science & Business Media
ISBN: 0387898484
Size: 24.38 MB
Format: PDF, ePub
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Due to its rapid development in recent years, hematopathology has become a very complicated discipline. The current development is mainly in two aspects: the new classification of lymphomas and leukemias and the new techniques. The Revised European-American Classification of Lymphoid Neoplasms (REAL classification) and the World Health Organization (WHO) classification of hematologic neoplasms require not only morphologic criteria but also immunophenotyping and molecular genetics for the diagnosis of hematologic tumors. Immunophenotyping is performed by either flow cytometry or immunohistochemistry. There are many new monoclonal antibodies and new equipments accumulated in recent years that make immunophenotyping more or more accurate and helpful. There are even more new techniques invented in recent years in the field of molecular genetics. In cytogenetics, the conventional karyotype is supplemented and partly replaced by the fluorescence in situ hybridization (FISH) technique. The current development of gene expression profiling is even more powerful in terms of subtyping the hematologic tumors, which may help guiding the treatment and predict the prognosis. In molecular biology, the tedious Southern blotting technique is largely replaced by polymerase chain reaction (PCR). The recent development in reverse-transcriptase PCR and quantitative PCR makes these techniques even more versatile. Because of these new developments, hematopathology has become too complicated to handle by a general pathologist. Many hospitals have to hire a newly trained hematopathologist to oversee peripheral blood, bone marrow and lymph node examinations. These young hematopathologists are geared to the new techniques, but most of them are inexperienced in morphology. No matter how well-trained a hematopathologist is, he or she still needs to see enough cases so that they can recognize the morphology and use the new techniques to substantiate the diagnosis. In other words, morphology is still the basis for the diagnosis of lymphomas and leukemias. Therefore, a good color atlas is the most helpful tool for these young hematopathologists and for the surgical pathologists who may encounter a few cases of hematologic tumors from time to time. In a busy daily practice, it is difficult to refer to a comprehensive hematologic textbook all the time. There are a few hematologic color atlases on the market to show the morphology of the normal blood cells and hematologic tumor cells. These books are helpful but not enough, because tumor cell morphology is variable from case to case and different kinds of tumor cells may look alike and need to be differentiated by other parameters. The best way to learn morphology is through the format of clinical case study. This format is also consistent with the daily practice of hematopathologists and with the pattern in all the specialty board examinations. Therefore, it is a good learning tool for the pathology residents, hematology fellows as well as medical students. This proposed book will present 83 clinical cases with clinical history, morphology of the original specimen and a list of differential diagnoses. This is followed by further testing with pictures to show the test results. At the end, a correct diagnosis is rendered with subsequent brief discussion on how the diagnosis is achieved. A few useful references will be cited and a table will be provided for differential diagnosis in some cases. The major emphasis is the provision of 500 color photos of peripheral blood smears, bone marrow aspirates, core biopsy, lymph node biopsy and biopsies of other solid organs that are involved with lymphomas and leukemias. Pictures of other diagnostic parameters, such as flow cytometric histograms, immunohistochemical stains, cytogenetic karyotypes, fluorescence in situ hybridization and polymerase chain reaction, will also be included. A comprehensive approach with consideration of clinical, morphologic, immunophenotypic and molecular genetic aspects is the best way to achieve a correct diagnosis. After reading this book, the reader will learn to make a diagnosis not only based on the morphology alone but also in conjunction with other parameters.

Hematopathology E Book

Author: Elaine Sarkin Jaffe
Publisher: Elsevier Health Sciences
ISBN: 032338871X
Size: 32.17 MB
Format: PDF, Docs
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The world's leading reference in hematopathology returns with this completely updated second edition. Authored by international experts in the field, it covers a broad range of hematologic disorders -- both benign and malignant -- with information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. Comprehensive in scope, it's a must-have resource for both residents and practicing pathologists alike. Authored by the chief architects of the WHO classification in neoplasms of hematopoietic and lymphoid tissue. Covers the newest diagnostic techniques, including molecular, immunohistochemical, and genetic studies. Confirm or challenge your diagnostic interpretations by comparing specimens to over 1,000 high-quality color images. Boasts detailed, practical advice from world leaders in hematopathology. Places an emphasis on pathologic diagnoses, including molecular and genetic testing. Updated with the most current WHO classifications of hematologic disease, including lymphoma and leukemia and peripheral T-cell lymphomas. Covers hot topics in hematopathology, such as the latest genetic insights into lymphoma and leukemia; the new nomenclature for myelodysplastic syndromes; new developments on the subject of Grey zone lymphoma; and much more.

Hematopathology Pearls

Author: Zhang Da
Publisher: JAYPEE BROTHERS MEDICAL PUBLISHERS PVT. LTD.
ISBN: 9350907445
Size: 60.32 MB
Format: PDF, ePub
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Doody Rating : 3 stars : This book Hematopathology Pearls providing high-yield information in preparation for a hematopathology rotation, residents and hematopathology fellows in service examination, board examination and hematopathology board re-certifications. Collection of approximately 280 full color microphotographs printed in large format, with detailed descriptions, markings, and annotations. It is a study guide for medical students, pathology residents, hematopathology fellows, hematopathologists and teachers of pathology.

Hematopathology

Author: Eric D. Hsi
Publisher: Elsevier Health Sciences
ISBN: 1437726062
Size: 20.15 MB
Format: PDF
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Hematopathology, a volume in the Foundations in Diagnostic Pathology Series, packs all of today's essential know-how into a concise, high-yield format! This medical reference book's well-organized approach, full-color illustrations, and at-a-glance tables make the information you need easy to find, so you can diagnose the most commonly encountered hematologic conditions as efficiently and accurately as possible. Efficiently diagnose the most commonly encountered neoplastic and non-neoplastic conditions of the hematologic system. Review normal histology before examining abnormal findings. Reference information quickly with a user-friendly format that explores each entity's clinical features, pathologic features, ancillary studies, differential diagnosis, and prognostic and therapeutic considerations. View key features of a wide variety of pathologies with hundreds of full-color illustrations. Check out the latest in the labs with new chapters on splenic pathology and flow cytometry. Get even more of the information you need with an expanded molecular pathology chapter than now highlights molecular diagnosis of red cell disorders. Access the full text and download images at expertconsult.com. The Foundations in Diagnostic Pathology Series answers the call for fresh, affordable, and easy-to-use guidance. Each region-specific volume provides all of the most essential information on the pathologic entities encountered in practice. Series Editor: John R. Goldblum, MD, FACP, FASCP, FACG A quick and easy reference, as a refresher or for those just starting out, on hematopathology.