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Human Herpesviruses Hhv 6a Hhv 6b And Hhv 7

Author: Louis Flamand
Publisher: Elsevier
ISBN: 0444627162
Size: 36.77 MB
Format: PDF, ePub, Mobi
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Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases. Delivers the latest molecular diagnostic tests, the present-day gold standard for monitoring HHV-6 Provides expert analysis of T-cell immune response against HHV-6 Presents tools for differential diagnosis in HHV-6 viral infections Includes new information on the previously-largely-unknown biological consequences of ciHHV-6 Offers coverage of new discoveries relating to HHV-7

The Cervix

Author: Joseph Jordan
Publisher: John Wiley & Sons
ISBN: 1444312758
Size: 28.18 MB
Format: PDF, ePub
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At over 600 pages, with more than 400 illustrations and photographs this text spans everything from embryology to the emotional trauma women undergo when their cervix is removed at hysterectomy. This is also the most up-to-date text in the field - The editors have referenced work to 2006(and will continue to until the text goes to press), whilst still including all the classic research material and images where appropriate. Essential for gynecologists, oncologists, basic scientists especially those involved in HPV (viral)research, GPs, nurses, colposcopy prctitioners, and sexual transmitted disease doctors The only definitive major clinical reference book published on the cervix for thirty years Including the most up-to-date research on HPV including up-to-date vaccine trial data Highly illustrated in colour including many surgical procedures Spanning the entire field from embryology to cancer to emotional trauma International editorship, with leading names in the field Cervical cancer is the second biggest cause of female cancer mortality worldwide and therefore relevant to the developing and developed world Specific chapters related to management of cervical cancer in the developing world Summaries of recommendations by international bodies including the IARC conference (Lyon 2004), dealing with cervical cancer diagnosis and treatment The Editors, Jordan and Singer, are the co-founders of the British Society for Colposcopy and Cervical Pathology

Management Of Infections In The Immunocompromised Host

Author: Brahm H. Segal
Publisher: Springer
ISBN: 3319776746
Size: 57.34 MB
Format: PDF, Kindle
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This book provides a comprehensive, state-of-the-art review of the concepts vital to a modern treatment of common and opportunistic infections in the immunocompromised host. Chapters are written by experts in the field, and include their views on gaps in the field and future directions of research. This book begins with an overview of the normally functioning immune system followed by a detailed discussion of the major primary immunodeficiencies. Specific chapters are dedicated to providing practical knowledge in the prevention and treatment of infections in specific immunocompromised patients, including those with cancer, transplant recipients, HIV infection, and autoimmune disorders. Emphasis is placed on diagnostic evaluation, antimicrobial selection that includes consideration of the threat of antimicrobial-resistant pathogens, and immunotherapy tailored to specific patients. Finally, dedicated chapters on stem cell transplantation for patients with primary immunodeficiencies, adoptive cellular immunotherapy, and gene therapy will provide readers with insight into these rapidly evolving and cutting edge therapies.Management of Infections in the Immunocompromised Host is a valuable resource for infectious diseases specialists, immunologists, oncologists, hematologists, general physicians, students, researchers, and all other working with immunocompromised patients.

Blood Banking And Transfusion Medicine

Author: Christopher D. Hillyer
Publisher: Elsevier Health Sciences
ISBN: 0443069816
Size: 71.68 MB
Format: PDF, ePub, Docs
View: 356
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Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.