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Handbook Of Models For Human Aging

Author: P. Michael Conn
Publisher: Elsevier
ISBN: 9780080460062
Size: 31.43 MB
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The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. Utilizes a multidisciplinary approach Shows tricks and approaches not available in primary publications First volume of its kind to combine both methods of study for human aging and animal models Over 200 illustrations

Physical Change And Aging Sixth Edition

Author: Sue V. Saxon, PhD
Publisher: Springer Publishing Company
ISBN: 0826198651
Size: 76.32 MB
Format: PDF, Docs
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"[This book] has been honed into an elegant compendium. This outstanding work should be widely read ñ it is perhaps the best example of an integrative approach to gerontology." Score: 94, 4 stars ñ Doody's "Phyisical Change & Aging has been a well-respected resource for caregivers ever since it was published in 1978. This updated version carries on the tradition of providing valuable information on the aging process and age-related health issues." ñ Former First Lady Mrs. Rosalynn Carter This sixth edition of a classic multidisciplinary text for students of gerontology continues to offer practical, reader-friendly information about the physical changes and common pathologies associated with the aging process. It places special emphasis on the psychological and social implications of these changes in the lives of older adults. The book is distinguished by its thorough focus on anatomy and physiology and common health problems pertaining to each body system. It emphasizes the positive aspects of aging and demonstrates how the elderly population can gain greater personal control, through lifestyle changes and preventive health strategies, toward the goal of optimal aging. This sixth edition has been thoroughly updated to present new research findings that differentiate "normal" aging from actual pathology and includes substantially updated information on diagnosis and treatment. It incorporates new data from healthy older adults demonstrating that the aging process is not necessarily as devastating as earlier research had indicated. The book provides new data and guidelines on risk factors, nutrition, preventive measures, interventions, and commonly prescribed medications, and includes expanded treatment of complementary and alternative therapies. Also included is an updated discussion of grief, ethical issues, and funeral options. The book reinforces information with practical applications of aging data. Written for students of gerontology, social work, human services, nursing, medicine, occupational and physical therapy, counseling, and elder law, it presents information that is clearly understandable for those without an extensive background in biology or medicine. Additionally, the book is a useful practitioner's guide and an easily understandable book for family caregivers. THIS SIXTH EDITION INCLUDES NEW INFORMATION ON: Diagnosis and treatment Behaviors and interventions that promote more control over an individual's aging process Genetic/DNA theories Dementia and Parkinson's disease Immunotherapy Lifelong health disparities Animal-assisted therapy Prayer and meditation Pharmacogenetics Geragogy (self-directed learning) Caregiver health as a public health issue Natural funerals (biodegradable caskets, burial urns, dying at home)

Molecular Basis Of Nutrition And Aging

Author: Marco Malavolta
Publisher: Academic Press
ISBN: 0128018275
Size: 10.81 MB
Format: PDF, ePub
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Molecular Basis of Nutrition and Aging: A Volume in the Molecular Nutrition Series focuses on the nutritional issues associated with aging and the important metabolic consequences of diet, nutrition, and health. The book is subdivided into four parts that reflect the impact of nutrition from a biomolecular level to individual health. In Part One, chapters explore the general aspects of aging, aging phenotypes, and relevant aspects of nutrition related to the elderly and healthy aging. Part Two includes molecular and cellular targets of nutrition in aging, with chapters exploring lipid peroxidation, inflammaging, anabolic and catabolic signaling, epigenetics, DNA damage and repair, redox homeostasis, and insulin sensitivity, among others. Part Three looks at system-level and organ targets of nutrition in aging, including a variety of tissues, systems, and diseases, such as immune function, the cardiovascular system, the brain and dementia, muscle, bone, lung, and many others. Finally, Part Four focuses on the health effects of specific dietary compounds and dietary interventions in aging, including vitamin D, retinol, curcumin, folate, iron, potassium, calcium, magnesium, zinc, copper, selenium, iodine, vitamin B, fish oil, vitamin E, resveratrol, polyphenols, vegetables, and fruit, as well as the current nutritional recommendations. Offers updated information and a perspectives on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of aging Explores how nutritional factors are involved in the pathogenesis of aging across body systems Investigates the molecular and genetic basis of aging and cellular senescence through the lens of the rapidly evolving field of molecular nutrition

Manson S Tropical Diseases E Book

Author: Jeremy Farrar
Publisher: Elsevier Health Sciences
ISBN: 0702053066
Size: 28.61 MB
Format: PDF, Mobi
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From the difficult to diagnose to the difficult to treat, Manson’s Tropical Diseases prepares you to effectively handle whatever your patients may have contracted. Featuring an internationally recognized editorial team, global contributors, and expert authors, this revised and updated medical reference book provides you with the latest coverage on parasitic and infectious diseases from around the world. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Incorporate the latest therapies into your practice, such as recently approved drugs and new treatment options. Find what you need easily and apply it quickly with highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams. Make the most accurate Tropical Disease diagnoses through a completely redesigned and modernized format, which includes full-color images throughout. Apply the latest treatment strategies for HIV/AIDS, tropical neurology, malaria, and much more. Put the latest international expertise to work for you and your patients with new chapters covering Global Health; Global Health Governance and Tropical Diseases; Non-communicable Diseases; Obesity in the Tropics; and Emergency and Intensive Care Medicine in Resource-poor Settings. See which diseases are most prevalent in specific areas of the tropics through a new index of diseases by country, as well as online-only maps that provide additional detail. Better understand the variations in treatment approaches across the globe.

Immunosenescence

Author: Graham Pawelec
Publisher: Springer Science & Business Media
ISBN: 9780387768427
Size: 73.45 MB
Format: PDF, ePub
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Human immunosenescence contributes to morbidity and mortality in later life. Understanding the reasons for age-associated alterations to protective immunity in the elderly would ultimately improve and extend healthspan. The majority of the papers collected in this remarkable and timely volume address the mechanisms responsible for immune ageing in humans. They also consider what might be accomplished to redress the erosion of immune competence with age.

Emerging Respiratory Infections In The 21st Century An Issue Of Infectious Disease Clinics E Book

Author: Alimuddin Zumla
Publisher: Elsevier Health Sciences
ISBN: 145570038X
Size: 77.98 MB
Format: PDF, ePub
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Respiratory infections are among the most common causes of morbidity and mortality worldwide. These infections present a special challenge to physicians for several reasons, including of the recent disasters caused by severe acute respiratory syndrome (SARS) and bird and swine influenza, the increase in viral and bacterial resistance to currently available anti-microbial drugs, the increased frequency of new viral lung infections in clinical practice, and the worldwide emergence of deadly drug-resistant forms of TB. For these reasons, it is important for infectious disease specialists to have an overview of emerging respiratory infections.

Advances In Geroscience

Author: Felipe Sierra
Publisher: Springer
ISBN: 3319232460
Size: 17.54 MB
Format: PDF, Kindle
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This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.

Handbook Of The Biology Of Aging

Author: Edward J. Masoro
Publisher: Academic Press
ISBN: 0120883872
Size: 76.13 MB
Format: PDF, Kindle
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This volume is a collection of 21 papers comprising conceptual and technical issues, non-mammalian models and mammalian models and including issues such as aging of the female reproductive system and computer modelling in the study of aging.

Cardiovascular Prevention And Rehabilitation

Author: Joep Perk
Publisher: Springer Science & Business Media
ISBN: 9781846289934
Size: 66.49 MB
Format: PDF
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This book is a timely and thorough review of prevention, lifestyle counseling and rehabilitation for cardiologists and all physicians and other health professionals in cardiac rehabilitation teams. The Editors have gathered over 60 experts from all parts of the globe. Each highlights the role of cardiac rehabilitation and preventative cardiology from exercise testing and training, through nutrition, smoking cessation, behavioral and social support to adapted programs for newer groups with specific demands. The book emphasizes the organizational aspects of cardiac rehabilitation, including quality assurance and economic evaluation.

Frontiers In Neurodegenerative Disorders And Aging

Author: Tomris Özben
Publisher: IOS Press
ISBN: 9781586034283
Size: 59.94 MB
Format: PDF
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This book brings together some of the best researchers in the field of aging and neurodegenerative diseases and presents up-to-date information concerning new developments in this exciting area of research in quite separate fields of biomedical science. It includes a wide range of issues such as basic and applied concepts, methods, and techniques used in this area. The chapters examine and evaluate our understanding of the pathogenetic mechanisms involved in these fields such as increased protein oxidation and macromolecular modifications associated with aging. This is a novel strategy for the visualization of ROS-induced protein oxidation and protection by antioxidants in living cells using fluorescent probes, thermochemiluminescence (TCL) methodology for determination of the oxidative status of biological systems in experimental and clinical setups, protein degradation, proteasome inactivation observed in the aging process or caused by oxidative stress. Other topics addressed are the oxidative stress theory of aging, oxidation and removal of protein aggregates in neurodegeneration, causes and consequences of oxidative stress in Alzheimers disease, assessment of antioxidants as a therapeutic for neurodegenerative diseases, rafts and prions, the many forms of the prion protein and its subcellular pathways, signaling pathways in protection of neural tissues by ischemic and drug-induced preconditioning, folding of proteins associated with neurodegenerative disorders and aging and neuroprotection in immuno-mediated neurodegeneration from infection to autoimmunity.