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Life Threatening Effects Of Antipsychotic Drugs

Author: Peter Manu
Publisher: Academic Press
ISBN: 0128033908
Size: 64.42 MB
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Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects. Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness Discusses clozapine rechallenge after each of its serious adverse reactions Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy Includes data on post-mortem considerations

Life Threatening Effects Of Antipsychotic Drugs

Author: Peter Manu
Publisher: Academic Press
ISBN: 9780128033760
Size: 29.44 MB
Format: PDF, Mobi
View: 1561
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Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects. Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness Discusses clozapine rechallenge after each of its serious adverse reactions Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy Includes data on post-mortem considerations

Antipsychotics And Their Side Effects

Author: David M. Gardner
Publisher: Cambridge University Press
ISBN: 113949192X
Size: 59.93 MB
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With the remarkable expansion in the use of antipsychotics, concerns about their immediate, intermediate, and long-term adverse effects have intensified. Despite this, studies consistently show that monitoring of patients taking antipsychotics can be inadequate, haphazard, or worse. This book provides a comprehensive review of the adverse effects of this pharmacologically complex therapeutic class, covering all commonly used conventional and atypical agents. In the first section, each chapter provides background information about an adverse effect, reviews the evidence linking the effect to various antipsychotics, and provides specific detection and monitoring recommendations. The second section provides unique monitoring guides for each antipsychotic. The third section provides the clinician with a program to monitor patients over the long-term. By supporting rational treatment decisions and systematic adverse effect monitoring, Antipsychotics and their Side Effects provides the clinician with the necessary information and tools for optimizing the safe and effective long-term use of antipsychotic drugs.

Antipsychotic Drugs And Their Side Effects

Author: Thomas R.E. Barnes
Publisher: Academic Press
ISBN: 1483288102
Size: 10.34 MB
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In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use.

Essential Psychopharmacology

Author: S. M. Stahl
Publisher: Cambridge University Press
ISBN: 9780521641548
Size: 13.48 MB
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Much expanded, fully revised, and with many more new illustrations, this remains the essential text for anyone who has to master the complexities of psychopharmacology.

Adverse Effects Of Psychotropic Drugs

Author: John M. Kane
Publisher: Guilford Publications
ISBN: 9780898628852
Size: 43.38 MB
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Contents are arranged in sections on general issues; side effect profiles of specific drugs; neuromuscular, cardiovascular, convulsive, and endocrine effects; and special populations--children and the aged. A full appreciation of potential adverse effects is vital to clinical practice, and these contributions discuss effects ranging from minor nuisances to potentially fatal reactions. Annotation copyright by Book News, Inc., Portland, OR

Drug Induced Movement Disorders

Author: Stewart Factor
Publisher: John Wiley & Sons
ISBN: 140513755X
Size: 22.22 MB
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The second revised edition of this text will update and present current state of the art clinical approaches to this subject. This book will continue to be the source text of information on drug-induced movement disorders authored and edited by the pioneers in the field. It will be an invaluable addition to the library of any neurologist.

The Myth Of The Chemical Cure

Author: J. Moncrieff
Publisher: Springer
ISBN: 0230589448
Size: 50.40 MB
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This book overturns the idea that psychiatric drugs work by correcting chemical imbalance and analyzes the professional, commercial and political vested interests that have shaped this view. It provides a comprehensive critique of research on drugs including antidepressants, antipsychotics and mood stabilizers.

Mad In America

Author: Robert Whitaker
Publisher: Basic Books
ISBN: 0786723793
Size: 16.21 MB
Format: PDF
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Schizophrenics in the United States currently fare worse than patients in the world's poorest countries. In Mad in America, medical journalist Robert Whitaker argues that modern treatments for the severely mentally ill are just old medicine in new bottles, and that we as a society are deeply deluded about their efficacy. The widespread use of lobotomies in the 1920s and 1930s gave way in the 1950s to electroshock and a wave of new drugs. In what is perhaps Whitaker's most damning revelation, Mad in America examines how drug companies in the 1980s and 1990s skewed their studies to prove that new antipsychotic drugs were more effective than the old, while keeping patients in the dark about dangerous side effects. A haunting, deeply compassionate book—now revised with a new introduction—Mad in America raises important questions about our obligations to the mad, the meaning of “insanity,” and what we value most about the human mind.