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Life Threatening Effects Of Antipsychotic Drugs

Author: Peter Manu
Publisher: Academic Press
ISBN: 0128033908
Size: 21.60 MB
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Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects. Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness Discusses clozapine rechallenge after each of its serious adverse reactions Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy Includes data on post-mortem considerations

Antipsychotic Drugs And Their Side Effects

Author: Thomas R.E. Barnes
Publisher: Academic Press
ISBN: 1483288102
Size: 78.20 MB
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In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use.

Mad In America

Author: Robert Whitaker
Publisher: Basic Books
ISBN: 0786723793
Size: 20.22 MB
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Schizophrenics in the United States currently fare worse than patients in the world's poorest countries. In Mad in America, medical journalist Robert Whitaker argues that modern treatments for the severely mentally ill are just old medicine in new bottles, and that we as a society are deeply deluded about their efficacy. The widespread use of lobotomies in the 1920s and 1930s gave way in the 1950s to electroshock and a wave of new drugs. In what is perhaps Whitaker's most damning revelation, Mad in America examines how drug companies in the 1980s and 1990s skewed their studies to prove that new antipsychotic drugs were more effective than the old, while keeping patients in the dark about dangerous side effects. A haunting, deeply compassionate book—now revised with a new introduction—Mad in America raises important questions about our obligations to the mad, the meaning of “insanity,” and what we value most about the human mind.

Your Drug May Be Your Problem Revised Edition

Author: Peter Breggin
Publisher: Da Capo Press
ISBN: 073821180X
Size: 61.46 MB
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When first published in 1999, Your Drug May Be Your Problem was ahead of its time. The only book to provide an uncensored description of the dangers involved in taking every kind of psychiatric medication, it was also the first and only book to explain how to safely stop taking them. In the time elapsed, there have been numerous studies suggesting or proving the dangers of some psychiatric medications and even the FDA now acknowledges the problems; more studies are under way to determine their long-term and withdrawal effects. In the meantime, this book continues to be ever relevant and helpful. Fully updated to include study results and new medications that have come to market, Your Drug May Be Your Problem will help countless readers exert control over their own psychiatric treatment.

Encyclopedia Of Substance Abuse Prevention Treatment And Recovery

Author: Gary L. Fisher
Publisher: SAGE
ISBN: 1412950848
Size: 30.29 MB
Format: PDF, Kindle
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Substance abuse is one of the most frequent and serious problems encountered by human service workers, criminal justice professionals, and clinicians. Unfortunately, many professionals in these fields receive little, if any, formal training about this problem. Our planned encyclopedia presents state-of-the-art research and evidence-based applications in A-to-Z format. Rather than create a compendium of specific drugs and drug effects, for which there are any number of fine titles already available, the focus will be upon practical knowledge and skills for pre-service and in-service human service professionals, including substance abuse counselors and prevention specialists.

The Day The Voices Stopped

Author: Ken Steele
Publisher: Basic Books
ISBN: 9780786724789
Size: 58.86 MB
Format: PDF
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For thirty-two years Ken Steele lived with the devastating symptoms of schizophrenia, tortured by inner voices commanding him to kill himself, ravaged by the delusions of paranoia, barely surviving on the ragged edges of society. In this inspiring story, Steele tells the story of his hard-won recovery from schizophrenia and how activism and advocacy helped him regain his sanity and go on to give hope and support to so many others like him.

Pharmacological Treatment Of Mental Disorders In Primary Health Care

Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241547693
Size: 20.13 MB
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This manual attempts to provide simple, adequate and evidence-based information to health care professionals in primary health care especially in low- and middle-income countries to be able to provide pharmacological treatment to persons with mental disorders. The manual contains basic principles of prescribing followed by chapters on medicines used in psychotic disorders; depressive disorders; bipolar disorders; generalised anxiety and sleep disorders; obsessive compulsive disorders and panic attacks; and alcohol and opioid dependence. The annexes provide information on evidence retrieval, assessment and synthesis and the peer view process.

Evidence Based Practice Of Palliative Medicine

Author: Nathan E. Goldstein
Publisher: Elsevier Health Sciences
ISBN: 143773796X
Size: 38.54 MB
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"Evidence-Based Practice of Palliative Medicine" is the only book that uses a practical, question-and-answer approach to address evidence-based decision making in palliative medicine. Dr. Nathan E. Goldstein and Dr. R. Sean Morrison equip you to evaluate the available evidence alongside of current practice guidelines, so you can provide optimal care for patients and families who are dealing with serious illness.

Antipsychotics And Their Side Effects

Author: David M. Gardner
Publisher: Cambridge University Press
ISBN: 113949192X
Size: 26.96 MB
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With the remarkable expansion in the use of antipsychotics, concerns about their immediate, intermediate, and long-term adverse effects have intensified. Despite this, studies consistently show that monitoring of patients taking antipsychotics can be inadequate, haphazard, or worse. This book provides a comprehensive review of the adverse effects of this pharmacologically complex therapeutic class, covering all commonly used conventional and atypical agents. In the first section, each chapter provides background information about an adverse effect, reviews the evidence linking the effect to various antipsychotics, and provides specific detection and monitoring recommendations. The second section provides unique monitoring guides for each antipsychotic. The third section provides the clinician with a program to monitor patients over the long-term. By supporting rational treatment decisions and systematic adverse effect monitoring, Antipsychotics and their Side Effects provides the clinician with the necessary information and tools for optimizing the safe and effective long-term use of antipsychotic drugs.