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Maternal Substance Abuse And The Developing Nervous System

Author: Ian S. Zagon
Publisher: Elsevier
ISBN: 0080926673
Size: 77.64 MB
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The purpose of this book is to review the basic science and clinical findings concerning maternal substance abuse and the developing nervous system of unborn children. The short-term but vitally significant repercussions of such exposure on biological development, with particular reference to the nervous system, are discussed. The book also discusses the profound influence of maternal substance abuse on behavior in adulthood, which is caused by subtle changes in the chemistry or structure of the developing nervous system. The subject will not only be of interest to clinical and basic science researchers and teachers in the field of maternal substance abuse, but also to individuals in psychology, social work, cellular and molecular biolgoy, embryology, neuroscience, pharmacology, and in clinical professions such as pediatrics, neonatology, and obstetrics. The breadth of topics covered includes alcohol, cocaine, opiates, nicotine, benzodiazepines, marijuana, and the role of stress and hormones. Emphasis is placed on the relationship of the effects of substance abuse on neurotrophic factors and receptors. Shows how abused substances act directly or indirectly to mimic or influence the action of neurotrophic factors Explains that the transient expression of peptides, neurotransmitters, and receptors can be markedly disturbed by drugs Demonstrates that animal and tissue culture studies are consistent with clinical observations and important in understanding and ameliorating adverse actions of drugs in early life

Pathways Of Addiction

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 9780309175388
Size: 37.63 MB
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Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevance--to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.

Neurobiology Of Mental Illness

Author: Dennis S. Charney
Publisher: Oxford University Press
ISBN: 9780199857548
Size: 34.23 MB
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This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.

Receptors In The Developing Nervous System

Author: Ian S. Zagon
Publisher: Springer Science & Business Media
ISBN: 9401115443
Size: 75.96 MB
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Receptors for cell hormones, growth factors, Fourth, alterations in the development of neu and neurotransmitters are involved in the ral receptors may have profound implications control and modulation of an enormous array for the structure and function of the of biological processes. The development of organism. As much as possible, the reper these receptors has distinct spatial and tem cussions of disrupting the orchestration of poral arrangements, and alterations in this receptor development in the nervous system pattern during embryogenesis can have signi are discussed. In many instances, however, ficant consequences for the well-being of the we are just beginning to learn about some fetus, infant, child and adult. The developing receptors and the authors may not be in a nervous system is particularly dependent on position to discuss the consequences of recep receptors because its period of structural and tor dysfunction. functional organization extends through both In designing these two volumes, we have prenatal and postnatal phases. Moreover, asked major figures in each field to review the receptors are a key element in neural com literature, to apprise the audience of their munication in both the developing and adult latest findings, and to provide a perspective on organism, so that the ontogeny of receptors is the role of receptors in the developing nervous crucial in determining the myriad connections system. These books are intended to sum forming the circuitry of the nervous system.

Handbook Of Parenting

Author: Marc H. Bornstein
Publisher: Psychology Press
ISBN: 1135650594
Size: 58.44 MB
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Please see Volume I for a full description and table of contents for all four volumes.

Minority Students In Special And Gifted Education

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309170818
Size: 59.66 MB
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Special education and gifted and talented programs were designed for children whose educational needs are not well met in regular classrooms. From their inceptions, these programs have had disproportionate representation of racial and ethnic minority students. What causes this disproportion? Is it a problem? Minority Students in Special and Gifted Education considers possible contributors to that disparity, including early biological and environmental influences and inequities in opportunities for preschool and K-12 education, as well as the possibilities of bias in the referral and assessment system that leads to placement in special programs. It examines the data on early childhood experience, on differences in educational opportunity, and on referral and placement. The book also considers whether disproportionate representation should be considered a problem. Do special education programs provide valuable educational services, or do they set students off on a path of lower educational expectations? Would students not now placed in gifted and talented programs benefit from raised expectations, more rigorous classes, and the gifted label, or would they suffer failure in classes for which they are unprepared? By examining this important problem in U.S. education and making recommendations for early intervention and general education, as well as for changes in referral and assessment processes, Minority Students in Special and Gifted Education will be an indispensable resource to educators throughout the nation, as well as to policy makers at all levels, from schools and school districts to the state and federal governments.

Creasy And Resnik S Maternal Fetal Medicine Principles And Practice E Book

Author: Michael F Greene
Publisher: Elsevier Health Sciences
ISBN: 1437721354
Size: 29.73 MB
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In your practice, you require advanced knowledge of the obstetrical, medical, genetic and surgical complications of pregnancy and their effects on the mother and fetus. With both basic science and clinical information, six new chapters, and an updated color design, you need look no further than the 6th edition of this long-time best seller. Includes both basic science and clinical information to give you comprehensive knowledge of the biology of pregnancy. Acts as an excellent resource for OB/GYNs studying for their Maternal-Fetal Medicine boards — and for practitioners who need quick access to practical information. Provides an updated and focused reference list to keep you up to date on the standards of care in maternal-fetal medicine today. Keeps you current with a new section: Disorders at the Maternal-Fetal Interface...and 6 new chapters: Biology of Parturition, Developmental Origins of Health and Disease, Intrapartum Assessment of Fetal Health, Pathogenesis of Pre-term Birth, Maternal and Fetal Infectious Disorders, and Benign Gynecological Conditions of Pregnancy. Features over 50% new authorship with increased focus on international perspectives. Includes the following hot topics in Maternal-Fetal Medicine: o Biology of Parturition o Fetal Growth o Prenatal Genetic Screening and Diagnosis o Fetal Cardiac Malformations and Arrhythmias o Thyroid Disease and Pregnancy o Management of Depression and Psychoses during Pregnancy and the Puerperium Focuses on evidence based medicine, the current best practice in MFM for diagnosing and treating high risk pregnancies. Includes new illustrations and an updated, color design.

Psychiatry

Author: Allan Tasman
Publisher: John Wiley & Sons
ISBN: 1118753364
Size: 16.27 MB
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Now in a new Fourth Edition, Psychiatry remains the leading reference on all aspects of the current practice and latest developments in psychiatry. From an international team of recognised expert editors and contributors, Psychiatry provides a truly comprehensive overview of the entire field of psychiatry in 132 chapters across two volumes. It includes two new sections, on psychosomatic medicine and collaborative care, and on emergency psychiatry, and compares Diagnostic and Statistical Manual (DSM-5) and International Classification of Diseases (ICD10) classifications for every psychiatric disorder. Psychiatry, Fourth Edition is an essential reference for psychiatrists in clinical practice and clinical research, residents in training, and for all those involved in the treatment psychiatric disorders. Includes a a companion website at www.tasmanpsychiatry.com featuring PDFs of each chapter and downloadable images

Alcohol And The Brain

Author: R.E. Tarter
Publisher: Springer Science & Business Media
ISBN: 1475791348
Size: 20.82 MB
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Chronic and excessive alcohol consumption disrupts a number of biologic sys tems. Central nervous system pathology, associated with long-standing alcohol ingestion, has particularly deleterious consequences to the individual. Compro mising brain functional integrity ultimately militates against psychosocial ad justment, and this process is inevitably reflected as a substantial economic loss to society in the form of costs for providing medical and social services, as well as disability and absenteeism from work. This book marshals the literature pertinent to the effects of chronic alcohol abuse on brain structure and functioning. The material is divided into two parts: basic research and clinical issues. In the first section, the manifest neurologic consequences are described across the different levels of biologic organization, these being brain morphology, neurochemistry, neurophysiology, and neuro psychology. In recognition of the multifactorial etiology of alcohol-related brain pathology, the influence and role of hepatic, endocrine, and nutritional factors are also examined. The second section addresses clinical syndromes and dis orders. It will be noted that evidence accrued from recent research suggests that neurologic disturbances may actually antedate the onset of drinking in some alcoholics. Other clinically important issues discussed are the effects of alcohol on neurologic development, aging, and dementia. The book concludes with a discussion of the alcohol withdrawal syndrome, its mechanisms and manifes tations. A fundamental objective of the editors was to illustrate that the consequences of chronic alcohol excess can be comprehensively understood within the per spective of interrelated hierarchical systems of brain organization.

Substance Abuse During Pregnancy An Issue Of Obstetrics And Gynecology Clinics

Author: Hilary Smith Connery
Publisher: Elsevier Health Sciences
ISBN: 032329944X
Size: 15.64 MB
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This issue of Obstetrics and Gynecology Clinics of North America deals with the timely subject of substance use during pregnancy. Alcohol, tobacco, and illicit drug use is prevalent among reproductive-age women. Even though a reduction in use often occurs during pregnancy, many women continue to use substances until a pregnancy is either actually diagnosed or well underway.This issue consists of a well-qualified team of obstetricians-gynecologists, psychiatrists, and family physicians, focusing on various issues related directly to pregnancies complicated by substance use. Topics of interest include epidemiology and screening for hazardous and harmful substance use, teratogenic risks, psychiatric comorbidities, comprehensive treatment approaches before and after delivery, fetal surveillance, and team-based perinatal management. Particularly new information relates to prescribing buprenorphine, neonatal abstinence syndrome, and adolescent substance use.