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Methods In Molecular Biophysics

Author: Nathan R. Zaccai
Publisher: Cambridge University Press
ISBN: 1107056373
Size: 29.44 MB
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A comprehensive graduate textbook explaining key physical methods in biology, reflecting the very latest research in this fast-moving field.

Methods In Molecular Biophysics

Author: Igor N. Serdyuk
Publisher: Cambridge University Press
ISBN: 1139461583
Size: 60.88 MB
Format: PDF
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Our knowledge of biological macromolecules and their interactions is based on the application of physical methods, ranging from classical thermodynamics to recently developed techniques for the detection and manipulation of single molecules. These methods, which include mass spectrometry, hydrodynamics, microscopy, diffraction and crystallography, electron microscopy, molecular dynamics simulations, and nuclear magnetic resonance, are complementary; each has its specific advantages and limitations. Organised by method, this textbook provides descriptions and examples of applications for the key physical methods in modern biology. It is an invaluable resource for undergraduate and graduate students of molecular biophysics in science and medical schools, as well as research scientists looking for an introduction to techniques beyond their specialty. As appropriate for this interdisciplinary field, the book includes short asides to explain physics aspects to biologists and biology aspects to physicists.

Methods In Molecular Biophysics

Author: Nathan R. Zaccai
Publisher: Cambridge University Press
ISBN: 1108508804
Size: 22.56 MB
Format: PDF, Docs
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Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.

Molecular Simulations And Biomembranes

Author: Mark S. P. Sansom
Publisher: Royal Society of Chemistry
ISBN: 0854041893
Size: 73.40 MB
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The need for information in the understanding of membrane systems has been caused by three things - an increase in computer power; methodological developments and the recent expansion in the number of researchers working on it worldwide. However, there has been no up-to-date book that covers the application of simulation methods to membrane systems directly and this book fills an important void in the market. It provides a much needed update on the current methods and applications as well as highlighting recent advances in the way computer simulation can be applied to the field of membranes and membrane proteins. The objectives are to show how simulation methods can provide an important contribution to the understanding of these systems. The scope of the book is such that it covers simulation of membranes and membrane proteins, but also covers the more recent methodological developments such as coarse-grained molecular dynamics and multiscale approaches in systems biology. Applications embrace a range of biological processes including ion channel and transport proteins. The book is wide ranging with broad coverage and a strong coupling to experimental results wherever possible, including colour illustrations to highlight particular aspects of molecular structure. With an internationally respected list of authors, its publication is timely and it will prove indispensable to a large scientific readership.

Molecular Biophysics

Author: Michel Daune
Publisher: Oxford University Press, USA
ISBN: 9780198577836
Size: 46.56 MB
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This new textbook offers a comprehensive introduction to the molecular physics of biological systems: it seeks to explain how the laws and concepts of physics apply to the living world at the molecular and subcellular level, with an emphasis on electrical and dynamical behaviour. The book is organized into five parts: * conformation of biopolymers * dynamics of biopolymers * hydration of biopolymers * biopolymers as polyelectrolytes *association between molecules The author adopts a multi-disciplinary approach and limits mathematics only to what is strictly necessary for the development of the subject. The text should be suitable for students from a wide range of backgrounds in biology, physics or chemistry taking advanced courses in molecular biophysics or biophysical chemistry.

The Physical Basis Of Biochemistry

Author: Peter R. Bergethon
Publisher: Springer Science & Business Media
ISBN: 9780387982625
Size: 38.37 MB
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The Physical Basis of Biochemistry is a rigorous, imaginative textbook that applies physical and chemical principles to understanding the bi ology of cells. The book features numerous problem sets and examples, clear illustrations, and extensive appendices that provide additional information on mathematics, physics and chemistry topics that support the text. The Physical Basis of Biochemistry is suitable for graduate and advanced undergraduate courses in physical biochemistry, biophysic al chemistry, and physical chemistry with application in the life scie nces. It will be welcomed by instructors seeking a text which combines a quantitative approach with a consistent biological perspective.

Molecular Biophysics For The Life Sciences

Author: Norma M. Allewell
Publisher: Springer Science & Business Media
ISBN: 1461485487
Size: 55.81 MB
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This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.

The Physics Of Proteins

Author: Hans Frauenfelder
Publisher: Springer Science & Business Media
ISBN: 9781441910448
Size: 57.63 MB
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Provides an introduction to the structure and function of biomolecules --- especially proteins --- and the physical tools used to investigate them The discussion concentrates on physical tools and properties, emphasizing techniques that are contributing to new developments and avoiding those that are already well established and whose results have already been exploited fully New tools appear regularly - synchrotron radiation, proton radiology, holography, optical tweezers, and muon radiography, for example, have all been used to open new areas of understanding

A Short Introduction To Quantum Information And Quantum Computation

Author: Michel Le Bellac
Publisher: Cambridge University Press
ISBN: 9781139457040
Size: 27.57 MB
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Quantum information and computation is a rapidly expanding and cross-disciplinary subject. This book, first published in 2006, gives a self-contained introduction to the field for physicists, mathematicians and computer scientists who want to know more about this exciting subject. After a step-by-step introduction to the quantum bit (qubit) and its main properties, the author presents the necessary background in quantum mechanics. The core of the subject, quantum computation, is illustrated by a detailed treatment of three quantum algorithms: Deutsch, Grover and Shor. The final chapters are devoted to the physical implementation of quantum computers, including the most recent aspects, such as superconducting qubits and quantum dots, and to a short account of quantum information. Written at a level suitable for undergraduates in physical sciences, no previous knowledge of quantum mechanics is assumed, and only elementary notions of physics are required. The book includes many short exercises, with solutions available to instructors through [email protected]