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Micro Reaction Technology In Organic Synthesis

Author: Charlotte Wiles
Publisher: CRC Press
ISBN: 9781439824726
Size: 60.22 MB
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While continuous processes have found widespread application within chemical production, members of the research and development communities have historically favored the centuries old technique of iterative batch reactions. With the exception of combinatorial and microwave chemistry, little had been done to change the way that synthetic chemists conduct their research. However, today’s synthetic chemist is under increasing pressure to discover and deliver compounds quickly, with an eye on devising scalable synthetic methodologies. An up-to-date account of recent developments in continuous flow organic synthesis, Micro Reaction Technology in Organic Synthesis is a useful resource for those both new to, and actively researching within, the field of micro reaction technology. Written by chemists for chemists, key synthetic information takes precedence over technological details Highlights the advantages and disadvantages of the technology, giving the reader an idea of where future research needs to be targeted Presents a comprehensive collection of synthetic reactions that have been investigated over the past decade, therefore is a one-stop resource to the reactions and techniques that have been investigated so far With an ever increasing number of commercial flow reaction platforms available, this book highlights the current state of the technology with the vision that more synthetic chemists will embark upon flow chemistry programs of research, facilitating the identification of novel synthetic methodologies the potential to be scaled directly to production.

Microreaction Technology Industrial Prospects

Author: W. Ehrfeld
Publisher: Springer Science & Business Media
ISBN: 3642597386
Size: 41.64 MB
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Miniaturization has cost and time-saving advantages for numerous applications in chemistry, pharmacy, medicine and biotechnology. Additionally, microreaction technology offers new solutions for the automobile industry and environmental technology, e.g. fuel cells, or mobile sensor systems for on-the-spot analysis. Therefore, the 3rd International Conference on Microreaction Technology - IMRET 3 is an important forum for creating awareness of the wide variety of the new trends in this up-and-coming discipline.

Chemical Micro Process Engineering

Author: Volker Hessel
Publisher: John Wiley & Sons
ISBN: 3527606270
Size: 71.58 MB
Format: PDF
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Micro process engineering is approaching both academia and industry. With the provision of micro devices, systems and whole plants by commercial suppliers, one main barrier for using these units has been eliminated. This book focuses on processes and their plants rather than on devices: what is 'before', 'behind' and 'around' micro device fabrication - and gives a comprehensive and detailed overview on the micro-reactor plants and three topic-class applications which are mixing, fuel processing, and catalyst screening. Thus, the book reflects the current level of development from 'micro-reactor design' to 'micro-reactor process design'.

Microreaction Technology

Author: Michael John Matlosz
Publisher: Springer Science & Business Media
ISBN: 9783540424987
Size: 55.76 MB
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The Fifth International Conference on Microreaction Technology featured more than 80 oral and poster communications, covering the entire interdisciplinary field from design, production, modelling and characterization of microreactor devices to application of microstructured systems for production, energy and transportation, including many analytical and biological applications.

Stereoselective Synthesis Of Drugs And Natural Products

Author: Vasyl Andrushko
Publisher: John Wiley & Sons
ISBN: 1118628330
Size: 56.26 MB
Format: PDF
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Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.

Basics Of Flow Microreactor Synthesis

Author: Jun-ichi Yoshida
Publisher: Springer
ISBN: 4431555137
Size: 14.23 MB
Format: PDF, ePub, Docs
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This book provides in a concise form the principles and applications of flow microreactors in organic and polymer synthesis. Recently, it became possible to conduct chemical reactions in a flow reactor in laboratory synthesis. The flow microreactor enables reactions that cannot be done in batch, opening a new possibility of chemical synthesis. Extremely fast mass and heat transfer and high-resolution residence time control are responsible for the remarkable features of that process. The book is not an exhaustive compilation of all known examples of flow microreactor synthesis. Rather, it is a sampling of sufficient variety to illustrate the concept, the scope, and the current state of flow microreactor synthesis. Researchers both in academia and in industry will be interested in this book because the topics encompassed by the book are vigorously studied in many university and company laboratories today.

Microreactors

Author: Wolfgang Ehrfeld
Publisher: Wiley-VCH
ISBN: 9783527295906
Size: 73.90 MB
Format: PDF
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Tiny devices with huge potential! New concepts of chemical synthesis have led to an increasing demand for miniaturization and more complex systems. Microreaction technology is a hot topic as it opens completely new possibilities for chemical engineering, combinatorial chemistry, and biotechnology. Small, inexpensive, independent, and versatile devices ensure many reactions achieve maximum selectivity, minimum waste, minimum investment, a better control of the process, safe manufacture and production on demand - to create a more efficient process. This book outlines the fabrication techniques of microfluidic components, unit operations of micro-chemical engineering and current world-wide activities. Requirements with respect to needs of the chemical industry have been included. Chemists, chemical engineers, biotechnologists, process engineers, microsystem technologists in the chemical and pharmaceutical industry and academia, as well as manufacturers of analytical instruments, will find this book a state-of- the-art review of this extremely interesting and rapidly developing field.

Microreactors In Preparative Chemistry

Author: Wladimir Reschetilowski
Publisher: John Wiley & Sons
ISBN: 3527652914
Size: 22.86 MB
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This is the first book in the field to focus on these aspects, providing extremely valuable information unavailable elsewhere for anyone seeking the practical application of microreactor technology in preparative chemistry. The topics covered branch out in three different directions. To begin with, the knowledge necessary for the preparative chemistry concerning the influence of the so-called microeffects on the reaction procedure and on mass and heat transfer as well as the surface phenomena are provided in detail. Next, practical aspects of the synthesis of various basic chemicals and fine chemicals, polymers, bioproducts and nanoparticles are discussed, including important advice for both the researcher and industrial chemist. Finally, reaction examples in microreactors whose reaction guidance are best understood are given together with universally applicable correlations as well as modeling approaches and transfer potential on related reaction systems. With its specific instructions, tips and experimental procedures for product syntheses as well as the inclusion of both the technical and theoretical background this is a must-have for beginners and experts alike working in this emerging field.

Microreactors In Organic Synthesis And Catalysis

Author: Thomas Wirth
Publisher: John Wiley & Sons
ISBN: 3527622861
Size: 52.28 MB
Format: PDF, Kindle
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This one-stop reference is the first book on this emerging and rapid developing field with a focus on synthesis and catalysis. As such, it covers all aspects from academia and industry in a clearly structured way. Leading experts provide the background information as an initial aid for newcomers to the field, while chapters on different reaction types and industrial applications make this an equally vital resource for specialists.

Applications

Author: Ferenc Darvas
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110367505
Size: 78.90 MB
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"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.