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The Double Helix

Author: James D. Watson
Publisher: Simon and Schuster
ISBN: 0743219171
Size: 78.16 MB
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The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

Molecular Biology Of The Gene

Author: James D. Watson
Publisher: Pearson Higher Ed
ISBN: 032189670X
Size: 26.10 MB
Format: PDF, Kindle
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This is the eBook of the printed book and may not include any media, website access codes, or print supplements that may come packaged with the bound book. Now completely up-to-date with the latest research advances, the Seventh Edition of James D. Watson’s classic book, Molecular Biology of the Gene retains the distinctive character of earlier editions that has made it the most widely used book in molecular biology. Twenty-two concise chapters, co-authored by six highly distinguished biologists, provide current, authoritative coverage of an exciting, fast-changing discipline.

Mechanisms Of Transcription

Author: Fritz Eckstein
Publisher: Springer Science & Business Media
ISBN: 3642606911
Size: 17.98 MB
Format: PDF
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Mechanisms of Transcription presents a unique perspective on the fundamental processes of transcription. A collection of distinguished authors draws together the underlying mechanisms involved in the process of transcription. This includes RNA polymerase function and its interaction with promoter sequences, and the structures of the various components on the transcriptional machinery. Both prokaryotic and eukaryotic systems, NMR and crystallographic structures of a number of important eukaryotic transcription factors are discussed, as well as the role of chromatin structure.

Gene Cloning And Dna Analysis

Author: T. A. Brown
Publisher: John Wiley & Sons
ISBN: 1119072557
Size: 41.48 MB
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Known world-wide as the standard introductory text to this important and exciting area, the seventh edition of Gene Cloning and DNA Analysis addresses new and growing areas of research whilst retaining the philosophy of the previous editions. Assuming the reader has little prior knowledge of the subject, its importance, the principles of the techniques used and their applications are all carefully laid out, with over 250 clearly presented four-colour illustrations. In addition to a number of informative changes to the text throughout the book, the chapters on DNA sequencing and genome studies have been rewritten to reflect the continuing rapid developments in this area of DNA analysis: In depth description of the next generation sequencing methods and descriptions of their applications in studying genomes and transcriptomes New material on the use of ChiP-seq to locate protein-binding sites Extended coverage of the strategies used to assemble genome sequences Description of how the Neanderthal genome has been sequenced and what that sequence tells us about interbreeding between Neanderthals and Homo sapiens Gene Cloning and DNA Analysis remains an essential introductory text to a wide range of biological sciences students; including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. It is also a perfect introductory text for any professional needing to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied and taught should have copies available on their shelves.

Molecular Biology Structure And Dynamics Of Genomes And Proteomes

Author: Jordanka Zlatanova
Publisher: Garland Science
ISBN: 1317633229
Size: 52.93 MB
Format: PDF, Docs
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Molecular Biology: Structure and Dynamics of Genomes and Proteomes illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. This textbook emphasizes the experimental basis of discovery and the most recent advances in the field while presenting a structural, mechanistic understanding of molecular biology that is rigorous, yet concise. The text is written for advanced undergraduate or graduate-level courses in molecular biology.

Genes And Signals

Author: Mark Ptashne
Publisher: CSHL Press
ISBN: 9780879696337
Size: 62.84 MB
Format: PDF
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Genes & Signals analyzes gene regulation from a new perspective. The first chapter describes mechanisms found in bacteria, and two subsequent chapters discuss which of these is most highly exploited in higher organisms. A final chapter relates these molecular strategies to other enzymatic processes, including those involving kinases, RNA splicing enzymes, proteases, and others. A general theme emerges, one that proposes how a rather restricted set of signals and enzymatic functions has been used in evolution to generate complex life forms of different types.

Molecular Biology Of The Cell

Author: Bruce Alberts
Publisher: Garland Science
ISBN: 1317563743
Size: 55.24 MB
Format: PDF, ePub, Docs
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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Cell Biology By The Numbers

Author: Ron Milo
Publisher: Garland Science
ISBN: 1317230698
Size: 30.57 MB
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Very little in our human experience is truly comparable to the immensely crowded and bustling interior of a cell. Biological numeracy provides a new kind of understanding of the cellular world. This book brings together up-to-date quantitative data from the vast biological literature and uses the powerful tool of "back of the envelope" estimates to reveal fresh perspectives and insights from numbers commonly encountered in cell biology. Readers gain a feeling for the sizes, concentrations, energies, and rates that characterize the lives of cellsÑ thereby shedding new light on the microscopic realm.

Molecular Biology Techniques

Author: Heather Miller
Publisher: Academic Press
ISBN: 0123855454
Size: 43.79 MB
Format: PDF, ePub
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This manual is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the techniques of recombinant DNA technology, or gene cloning and expression. The techniques used in basic research and biotechnology laboratories are covered in detail. Students gain hands-on experience from start to finish in subcloning a gene into an expression vector, through purification of the recombinant protein. The third edition has been completely re-written, with new laboratory exercises and all new illustrations and text, designed for a typical 15-week semester, rather than a 4-week intensive course. The “project approach to experiments was maintained: students still follow a cloning project through to completion, culminating in the purification of recombinant protein. It takes advantage of the enhanced green fluorescent protein - students can actually visualize positive clones following IPTG induction. Cover basic concepts and techniques used in molecular biology research labs Student-tested labs proven successful in a real classroom laboratories Exercises simulate a cloning project that would be performed in a real research lab "Project" approach to experiments gives students an overview of the entire process Prep-list appendix contains necessary recipes and catalog numbers, providing staff with detailed instructions

Lewin S Genes Xi

Author: Jocelyn E. Krebs
Publisher: Jones & Bartlett Publishers
ISBN: 1449659055
Size: 13.69 MB
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Molecular Biology is a rapidly advancing field with a constant flow of new information and cutting-edge developements that impact our lives. Lewin's GENES has long been the essential resource for providing the teaching community with the most modern presentation to this dynamic area of study. GENES XI continues this tradition by introducing the most current data from the field, covering gene structure, sequencing, organization, and expression. It has enlisted a wealth of subject-matter experts, from top institutions, to provide content updates and revisions in their individual areas of study. A reorganized chapter presentation provides a clear, more student-friendly introduction to course material than ever before. - Updated content throughout to keep pace with this fast-paced field. - Reorganized chapter presentation provides a clear, student-friendly introduction to course material. - Expanded coverage describing the connection between replication and the cell cycle is included, and presents eukaryotes as well as prokaryotes. - Available with new online Molecular Biology Animations. - Online access code for the companion website is included with every new book. The companion website offers numerous study aids and learning tools to help students get the most out of their course. - Instructor's supplements include: PowerPoint Image Bank, PowerPoint Lecture Slides, and Test Bank.