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Multiscale Technologies For Cryomedicine Implementation From Nano To Macroscale

Author: Bischof John C
Publisher: World Scientific
ISBN: 9814733202
Size: 43.84 MB
Format: PDF
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The use of micro / nanotechnology in cell and tissue engineering, and especially for cell and tissue preservation, is at the peak of its activity now, with scientific output expected to continue growing in the coming years.Micro and nanotechnologies have induced paradigm shifts in many scientific fields, and as featured in this edited volume, they are having important impact in the field of cryomedicine. The book gives an overview of the recent progress in implementing multiscale (micro and nanoscale) technologies to improve the outcome of various cryomedical applications including cryosurgery, cryopreservation, lyopreservation and to understand the fundamental engineering and science underpinning the applications.This is the first book that will provide both an introductory and in-depth account of applying the multiscale technologies in cryomedicine.

Cancer Therapeutics And Imaging Molecular And Cellular Engineering And Nanobiomedicine

Author: Rege Kaushal
Publisher: World Scientific
ISBN: 9813222565
Size: 45.47 MB
Format: PDF, ePub
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This book describes the latest advancements in molecular and cellular engineering approaches in addition to nanotechnology for cancer therapeutics and imaging. It also provides an excellent background and state-of-the-art developments in the fields of drug and gene delivery, engineering nanoparticles for therapy and diagnostics, and cancer imaging techniques. The contents of this book include chapters on cutting-edge science in molecular and cellular engineering and nanotechnology as applied to therapeutics and imaging in cancer diseases. The chapters also provide a comprehensive overview on gene therapy and delivery methods for cancer treatment, oral drug delivery and barriers, cancer imaging for diagnostics and therapy, and the latest developments in these fields. Contents: Optically Modulated Theranostic Nanoparticles (Niksa Valim & Amit Joshi)Gene Therapy Treatments for Cancer (Jacob Elmer)Nanocarrier based Pulmonary Gene Delivery for Lung Cancer: Therapeutic and Imaging Approaches (Nishant S Gandhi, Micah Glasgow & Mahavir B Chougule)Quantitative Contrast Enhanced Ultrasound Imaging in Cancer Therapy (Shashank R Sirsi & Mark A Borden)Multifunctional Dendritic Nanoparticles as a Nanomedicine Platform (Hao-jui Hsu, Ryan M Pearson & Seungpyo Hong)Oral Drug Delivery Systems for Gastrointestinal Cancer Therapy (Yue-Wern Huang & Sutapa Barua)Cancer Therapeutics with Light: Role of Nanoscale and Tissue Engineering in Photodynamic Therapy (Joyce Liu, Huang-Chiao Huang, Emma Briars, Girgis Obaid, Imran Rizvi & Tayyaba Hasan)Targeted Contrast Agents for 1H MRI of Tumor Microenvironment (Shubhangi Agarwal & Vikram D Kodibagkar)Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as Anti-Cancer Delivery Systems for Therapy and Diagnostics (Samuel V Mussi & Vladimir P Torchilin) Readership: Students and researchers in nanobiotechnology, nanomedicine, cancer research, bioengineering and medical imaging. Keywords: Nanobiotechnology;Nanomedicine;Nanoparticles;Cancer Research;Cancer Therapy;Gene Therapy;Bioengineering;Medical ImagingReview: Key Features: Novel aspects in cancer therapeutic delivery, comprehensive molecular and cellular aspects of cancer delivery and imaging, latest advanced in nanotechnology for cancer

Bioengineering In Wound Healing A Systems Approach

Author: Yarmush Martin L
Publisher: World Scientific
ISBN: 9813144599
Size: 77.37 MB
Format: PDF, Kindle
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What is a wound, how does it heal, and how can we prevent scarring? The concept of wound healing has puzzled humans even before the advent of modern medicine. In recent years, bioengineering has tackled the problems of cancer, tissue engineering and molecular manufacturing. The broad spectrum of technologies developed in these fields could potentially transform the wound care practice. However, entering the world of wound healing research is challenging — a broad spectrum of knowledge is required to understand wounds and improve healing. This book provides an essential introduction of the field of wound healing to bioengineers and scientists outside the field of medicine. Written by leading researchers from various fields, this book is a comprehensive primer that gives readers a holistic understanding of the field of wound biology, diagnostics and treatment technologies. Contents:Scarless Tissue Regeneration (Alexander Golberg)Anatomy of the Human Skin and Wound Healing (Amit Sharma, Labib R Zakka and Martin C Mihm Jr)Deprived and Enriched Environments: How Sensory Stimulation Affects Wound Healing (Jonathan G Fricchione and John B Levine)Models of Ischemic and Vascular Wounds (Michael T Watkins and Hassan Albadawi)Developmental Biology of Skin Wound Healing: On Pathways and Genes Controlling Regeneration Versus Scarring (Sarah Susan Kelangi and Marianna Bei)Nutrition, Metabolism, and Wound Healing Process (Yong-Ming Yu and Alan J Fischman)Polarization Sensitive Optical Coherence Tomography for Imaging of Wound Repair (Martin Villiger and Brett E Bouma)Functional Imaging of Wound Metabolism (Jake Jones, Vasily Belov and Kyle P Quinn)Functional Skin Substitutes — The Intersection of Tissue Engineering and Biomaterials (Kevin Dooley, Julie Devalliere and Basak Uygun)Biomaterial-Based Systems for Pharmacologic Treatment of Wound Repair (Mara A Pop, Julia B Sun and Benjamin D Almquist)Laser Tissue Welding in Wound Healing and Surgical Repair (Russell Urie, Tanner Flake and Kaushal Rege)Bioprinting for Wound Healing Applications (Aleksander Skardal, Sean Murphy, Anthony Atala and Shay Soker)Electroporation Applications in Wound Healing (Laure Gibot, Tadej Kotnik and Alexander Golberg) Readership: Bioengineers, scientists, researchers and graduate students outside the field of medicine.

An Introduction To Metabolic And Cellular Engineering

Author: S Cortassa
Publisher: World Scientific
ISBN: 9814489514
Size: 64.19 MB
Format: PDF
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Metabolic and cellular engineering, as presented in this book, is a powerful alliance of two technologies: genetics–molecular biology and fermentation technology. Both are driven by continuous refinement of the basic understanding of metabolism, physiology and cellular biology (growth, division, differentiation), as well as the development of new mathematical modeling techniques. The authors' approach is original in that it integrates several disciplines into a coordinated scheme, i.e. microbial physiology and bioenergetics, thermodynamics and enzyme kinetics, biomathematics and biochemistry, genetics and molecular biology. Thus, it is called a transdisciplinary approach (TDA). The TDA provides the basis for the rational design of microorganisms or cells in a way that has rarely been utilized to its full extent. Contents:Matter and Energy BalancesCell Growth and Metabolite Production. Basic ConceptsMethods of Quantitation of Cellular “Processes Performance”Dynamic Aspects of Bioprocess BehaviorBioprocess Development with Plant CellsCellular Engineering Readership: Undergraduates, graduates and researchers in biomedical engineering, biochemistry and biotechnology. Keywords:Reviews:“The book provides very well selected examples that permit an easy comprehension of the achievements expected from the different techniques. I consider the book suitable for both experimentalists and theoreticians … it also provides an excellent selection of key references on the main techniques available in the field which are very useful for students and research workers.”Marta Cascante Serratosa Professor of Biochemistry and Molecular Biology University of Barcelona “A worked example towards the end of the book of the use of such a scheme was most welcome. The book is aimed at final year undergraduates and postgraduate researchers and is suitable for personal purchase.”Microbiology Today

Tissue Regeneration

Author: Qing Liu
Publisher: World Scientific
ISBN: 9814494852
Size: 30.78 MB
Format: PDF, Kindle
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This unique volume presents the recent advances in tissue regeneration. The authors are all active researchers in their respective fields with extensive experiences. The focus of the book is on the use of stem cells and nano-structured biomaterials for tissue regeneration/tissue engineering. It includes the use of stem cells, naturally derived extracellular matrix (ECM), synthetic biomimetic nano-fibers, synthetic nano-structured ceramics and synthetic nano-structured polymer/ceramic composites that can help/promote tissue regeneration. Methods on how to produce these nano-structured biomaterials are also discussed in several chapters. Future challenges and perspectives in the field of regenerative medicine (tissue regeneration) are also discussed. Contents:Adult Stem Cells: From Bench-Top to Bedside (Henry E Young, Lee Hyer, Asa C Black Jr and Joe Sam Robinson Jr)Preparation of Tissue Development — Mimicking Matrices and Their Applications (Guoping Chen, Takashi Hoshiba and Naoki Kawazoe)Decellularized Scaffolds: Concepts, Methodologies, and Applications in Cardiac Tissue Engineering and Whole-Organ Regeneration (Sourav S Patnaik, Bo Wang, Benjamin Weed, Jason A Wertheim and Jun Liao)Recent Advances on Three-Dimensional Electrospun Nanofiber Scaffolds for Tissue Regeneration and Repair (Bing Ma, Matthew R MacEwan, Franklin D Shuler, Matthew K Wingate and Jingwei Xie)Nanofibrous Scaffolds for Tissue Engineering Applications: State-of-the-Art and Future Trends (Masoud Mozafari, Vahid Shabafrooz, Mostafa Yazdimamaghani, Daryoosh Vashaee and Lobat Tayebi)Extra Cellular Matrix and Its Application as Coating on Synthetic 3D Scaffolds for Guided Tissue Regeneration (Qing Liu and Marika K Bergenstock)Nanodimensional and Nanocrystalline Calcium Orthophosphates (Sergey V Dorozhkin)Nano-Bioceramics as Coatings for Orthopedic Implants and Scaffolds for Bone Regeneration (Yongxing Liu Mohamed N Rahaman and B Sonny Bal)Cell Behavior on Electrospun Scaffolds: Factors at Play on Nanoscale (Parthasarathy Madurantakam and Gary Bowlin)The Convergence of Biomimetic Nanofibers and Cells for Functional Tissue Formation (Xuening Chen, Licheng Wang and Hongjun Wang)Surface Structure of Nanocomposites and Its Properties: A Practical Example (Davide Barbieri, Joost D de Bruijn and Huipin Yuan) Readership: Professionals, researchers, graduate students in tissue engineering, biomedical engineering, bioengineering, nanobiotechnology and nanobiomaterials and clinical physicians. Keywords:Nanofiber;Stem Cells;Tissue Regeneration;Tissue Engineering;Extracellular Matrix;Nano Structure;Biomaterials;Biodegradable Polymer;Ceramics;Composite

A Manual For Laboratory Animal Management

Author: Jonathan David Ward
Publisher: World Scientific
ISBN: 9812779582
Size: 20.78 MB
Format: PDF
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Laboratory animal research remains a very important part of basic research and drug development. This book rectifies the problem by providing animal researchers and technicians with the essentials for conducting their work in the laboratory, offering detailed protocols and information that can be referred to on a daily basis.

Low Temperature And Cryogenic Refrigeration

Author: Sadik Kakaç
Publisher: Springer Science & Business Media
ISBN: 9401000999
Size: 34.41 MB
Format: PDF, ePub
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Refrigeration plays a prominent role in our everyday lives, and cryogenics plays a major role in medical science, space technology and the cooling of low-temperature electronics. This volume contains chapters on basic refrigeration systems, non-compression refrigeration and cooling, and topics related to global environmental issues, alternative refrigerants, optimum refrigerant selection, cost-quality optimization of refrigerants, advanced thermodynamics of reverse-cycle machines, applications in medicine, cryogenics, heat pipes, gas-solid absorption refrigeration, multisalt resorption heat pumps, cryocoolers, thermoacoustic refrigeration, cryogenic heat transfer and enhancement and other topics covering theory, design, and applications, such as pulse tube refrigeration, which is the most efficient of all cryocoolers and can be used in space missions.

Biobanking And Cryopreservation Of Stem Cells

Author: Feridoun Karimi-Busheri
Publisher: Springer
ISBN: 3319454579
Size: 58.53 MB
Format: PDF
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Biobanking is considered to be one of the ten ideas changing the world with an estimated value of $45 billion by 2025. Despite the challenges, as the climate for innovation in the biobanking industry continues to flourish around the world, it is certain that amazing discoveries will emerge from this large-scale method of preserving and accessing human samples; biobanking is no longer just a place for collecting and storing samples. This book will cover a wide variety of subjects from across the future biobanking spectrum including scientific strategies, personalized medicine, regenerative medicine and stem cell challenges, disease surveillance, population genetics and innovative methods of biobanking.

Adipose Derived Stem Cells

Author: Jeffrey M. Gimble
Publisher: Humana Press
ISBN: 9781617379598
Size: 11.51 MB
Format: PDF, ePub, Mobi
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During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.