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Muscle Metabolism

Author: Juleen R Zierath
Publisher: CRC Press
ISBN: 9780203166420
Size: 14.99 MB
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Diabetes research on models comprising intact animal tissues, cell cultures and isolated pancreatic islets is essential for understanding the pathogenesis of the disease as well as the mechanisms responsible for the chronic complications associated with it. Enormous advances in the understanding of the development of diabetes and its prevention have recently been derived from work with such animal models. This book presents the state-of-the-art knowledge in the field of diabetes research directed at understanding the mechanisms governing the development of skeletal muscle insulin resistance. Muscle Metabolism will be of significant interest for those researching diabetes at an experimental level in both academia and the pharmaceutical industry. In addition, it will also be of interest to researchers in the fields of obesity, metabolism, endocrinology and molecular biology.

Peroxisome Proliferator Activated Receptors From Basic Science To Clinical Applications

Author: J.-C. Fruchart
Publisher: Springer Science & Business Media
ISBN: 1461511712
Size: 44.13 MB
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Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. As a consequence, our knowledge of the role of these receptors in physiology and pathology continues to grow at a fast pace and PPARs have become an interesting target for the treatment of many pathological conditions, including diabetes and atherosclerosis. This volume provides an authoritative view of the current clinical and scientific developments within this evolving area of study.

Animal Models In Diabetes

Author: Eleazar Shafrir
Publisher: CRC Press
ISBN: 020330473X
Size: 17.35 MB
Format: PDF
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Animal Models of Diabetes: A Primer introduces characteristics of the most commonly used animal species with various diabetic syndromes which have been developed and extensively investigated during the last few decades. It includes animal models that are readily available, well described and proven to be of value in the research of both types of diabetes. Extensively referenced, this book will be of value to new and established investigators, graduate students and pharmaceutical scientists working on the development of antidiabetic and preventative modalities in various areas of diabetes and its complications.

Frontiers In Clinical Drug Research Diabetes And Obesity

Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 1681081857
Size: 75.83 MB
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Frontiers in Clinical Drug Research – Diabetes and Obesity is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The second volume of this series features 7 reviews presenting updates on hormones and several classes of drugs: -Osteocalcin action in glucose metabolism -Sodium-glucose co-transporter 2 (SGLT2) inhibitors -Glucagon-like peptide-1 (GLP-1) mimetics -Dipeptidyl peptidase 4 (DPP-4) inhibitors -New drugs in clinical trial and commercial phases

Endocrinology And Metabolism

Author: Paul W. Ladenson, M.D.
Publisher: Physician's Desk Reference (PDR)
ISBN: 9781563634673
Size: 70.59 MB
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Clear and concise Internet navigational directories designed to lead physicians directly to websites that have been reviewed by peer leaders and professionals in various medical specialties. Each guide focuses on a single specialty and reviews over 1,600 related websites. Unlike search engines, eMedguides list only authoritative sites that offer useful professional content. eMedguide reviews are posted and continuously updated at, where you can easily click directly to any website reviewed.

Clinical Diabetes Mellitus

Author: John K. Davidson
Publisher: Thieme
ISBN: 9780865778405
Size: 17.66 MB
Format: PDF, ePub
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Reviews of the first two editions: The primary source of information on diabetes for health professionals who deal with diabetic patients. - Annals of Internal Medicine Outstanding...the physician who is interested in diabetes mellitus should buy this book.-The New England Journal of Medicine Comprehensive and up-to-date...a solid introduction to the basic science of diabetes with a wealth of practical clinical information. - JAMA Do your patients ask you questions such as: What new types of insulin treatment are available? Why are pills not as safe and effective as insulin treatment? What is the genetic risk to an individual of developing diabetes? What can at-risk individuals do to prevent the onset of diabetes? For straightforward and informed answers to questions like these, turn to Clinical Diabetes Mellitus: A Problem Oriented Approach. The third edition of this acclaimed work represents the state-of-the-art in diabetes research, diagnosis, and management - in a unique problem-oriented format. Reflecting Dr. Davidson's more than 50 years of experience in the research and care of diabetic patients, this format offers direct solutions to the problems diabetes care professionals face everyday. The book features several new chapters and is divided into seven sections covering: the nature of diabetes mellitus; screening and diagnosis; long-term management; complications; concomitant problems; socioeconomic problems; and the development and evaluation of diabetes care programs. Inside, you'll find insightful analysis of epidemiology, pathophysiology, patient adherence, the latest research, and more. Plus, the book provides state-of-the-art information on everything from new insulin analogues and treatment methods to diabetes education and the significance of the Diabetes Control and Complications Trial. Highlights of the third edition: New chapters on cranial and peripheral neuropathy, autonomic neuropathy, and musculoskeletal problems in diabetes Comprehensive chapters on the team approach to diagnosis and treatment of diabetes with detailed information on how to deal with psychosocial problems New recommendations of the American Diabetes Association for the diagnosis of Type 1, Type 2, and gestational diabetes mellitus Thorough presentations on all diabetes related complications, including retinopathy, nephropathy, heart disease, cerebrovascular disease, and the diabetic foot Helpful information on the public health responses of the CDC and diabetes research programs of the NIDDK and NIH Contributions from 106 world-class authors from the U.S., Canada, and Europe For comprehensive, up-to-date, and clinically relevant information on diabetes mellitus, this book is unparalleled. It is an essential addition to the working library of diabetologists, endocrinologists, internists, family practitioners, and any member of the health care team involved in the treatment of the diabetic patient. It is also a must for medical school and hospital libraries.

Insulin Resistance And Insulin Resistance Syndrome

Author: Barbara Hansen
Publisher: CRC Press
ISBN: 0203217411
Size: 16.95 MB
Format: PDF, ePub
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Type II diabetes has developed into a global epidemic, with nearly 20 type II patients for every type I individual. Preceding the onset of type II diabetes is a prolonged episode of insulin resistance featuring a host of detrimental symptoms. This period comprises a disease referred to as Insulin Resistance Syndrome or Metabolic Syndrome. Insulin Resistance and Insulin Resistance Syndrome deals with the cellular and whole body pathogenic mechanisms and phenotypic expressions in various models of insulin resistance. Leaders in the field provide their perspectives on the mechanisms of insulin resistance, as observed in various animal models. While the exact mechanism underlying resistance to insulin is unknown, the authors review many of the significant factors. A series of chapters on Metabolic Syndrome discusses its possible insulin resistance-associated pathophysiology with obesity, cardiovascular disease, hypertension, glucose intolerance, and abnormalities in whole body metabolism. Presenting essential knowledge in the field of insulin resistance, this book will benefit clinicians, pharmaceutical scientists, and researchers involved in endocrinology, biochemistry and metabolism in diabetes.