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Pharmacoeconomics

Author: Renee J. G. Arnold
Publisher: CRC Press
ISBN: 9781420084405
Size: 77.28 MB
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The pharmaceutical industry is almost boundless in its ability to supply new drug therapies, but how does one decide which are the best medicines to use within restricted budgets? With particular emphasis on modeling, methodologies, data sources, and application to real-world dilemmas, Pharmacoeconomics: From Theory to Practice provides an introduction to the major concepts and principles of pharmacoeconomics and cost-effectiveness analysis (CEA). As a running theme, the book explores the collaboration among members of the pharmaceutical industry, academia, and government in the development of the human papillomavirus vaccine to demonstrate the full range of ethical and moral issues, as well as overall public health and commercial concerns that are often involved in decisions entailing CEA. Readers will learn about the international use of pharmacoeconomics in drug regulation, drug approval, and pricing, and the book provides examples of pharmacoeconomic models used to support these purposes in government, the pharmaceutical industry, and healthcare settings. In this era of finite budgets, healthcare rationing, medication shortages, and the global aging and burgeoning of populations, numerous stakeholders in the healthcare arena must understand the basic principles of pharmacoeconomics and how these may be correctly applied to facilitate drug development, drug approval, rationing, patient segmentation, disease management, and pricing model development. Focusing on how to save money, not by restricting access to necessary services, but by using available resources more efficiently and rationally, this volume arms decision makers with the tools they need to make wise choices in an area where the stakes are so high. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

Essentials Of Pharmacoeconomics

Author: Karen Rascati
Publisher: Lippincott Williams & Wilkins
ISBN: 146984186X
Size: 27.78 MB
Format: PDF, Docs
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This text provides a straightforward explanation of the essential pharmacoeconomics topics outlined by The Accreditation Council for Pharmacy Education (ACPE). It defines terminology used in research and covers the application of economic-based evaluation methods to pharmaceutical products and services, making it perfect for the student or practitioner who is unfamiliar with "pharmacoeconomics." Readers will find examples of how pharmacoeconomic evaluations relate to decisions that affect patient care and health-related quality of life. Understanding these principles will help you assess published research aimed at improving clinical and humanistic outcomes based on available resources. You’ll Find These Helpful Features Inside— · Composite research articles that include the positives and negatives found in published research which will help you learn to evaluate literature and to interpret and determine the usefulness of pharmacoeconomic research articles. · Composite worksheets increase your comprehension of just-read articles. · Examples provide and reinforce relevant illustrations of chapter content. · Questions/Exercises at the end of each chapter assess your understanding of the key concepts. · Common Equations that are critical to the subject are presented, with multiple example calculations that clearly demonstrate the use of these equations

Pharmacoeconomics

Author: Lorenzo Pradelli
Publisher: SEEd
ISBN: 8897419380
Size: 77.19 MB
Format: PDF, Docs
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Economic issues related to the health sector have been gaining much attention in recent years, and the challenge of providing quality and comprehensive health care to a growing population has become increasingly complex. This book’s aim is to introduce readers to basic principles of economics and to a set of analytical tools of economic evaluations and their application in the health sector. The most important evaluation techniques are explained by examples: cost-minimization analysis, cost-effectiveness analysis, cost-utility analysis and cost-benefit analysis.

Phage Display In Biotechnology And Drug Discovery Second Edition

Author: Sachdev S. Sidhu
Publisher: CRC Press
ISBN: 1439836507
Size: 25.95 MB
Format: PDF
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Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery and biotechnology. Building on the success of its previous edition, the book discusses current theories, principles, and methods in the field and demonstrates applications for peptide phage display, protein phage display, and the development of novel antibodies. The book provides readers with an overview of the amazing breadth of the impact that phage display technology has had on the study of proteins in general as well as the development of proteins. It will be a valuable resource for those interested in using phage display and recombinant antibodies in basic research and drug discovery.

Pharmacoinformatics And Drug Discovery Technologies Theories And Applications

Author: Gasmelseid, Tagelsir Mohamed
Publisher: IGI Global
ISBN: 1466603100
Size: 12.10 MB
Format: PDF, ePub, Mobi
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Within the context of integrated health management domains, pharmacoinformatics aims at maximizing the benefits from the use of information systems and technologies for the provision of decision support tools necessary for improved drug management, use, and administration practices. Pharmacoinformatics and Drug Discovery Technologies: Theories and Applications offers the latest the field has to offer to practitioners and academics alike, presented through theoretical frameworks, case studies, and future directions. This vital resource gathers an integrated pattern of high quality publications from around the world providing current, cutting-edge, and provocative scientific work in the three domains of pharmacoinformatics: decision making domains, knowledge utilization and representation environment, and the technological and infrastructural context.

The Clinical Practice Of Drug Information

Author: Michael Gabay
Publisher: Jones & Bartlett Publishers
ISBN: 128402623X
Size: 66.25 MB
Format: PDF, Kindle
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The Clinical Practice of Drug Information provides information on various resources, approaches to answering drug information requests, evaluating the biomedical literature, study design, statistical concepts, bioinformatics, medication safety, development of medication use policies, medication safety, formulary management, evidence-based medicine, and pharmacy informatics. This resources will educate students and pharmacists on traditional drug information topics while providing an extensive background on more recent practice areas. This is a user-friendly text with multiple examples that can be used in education and training, as well as clinical practice. Each chapter includes learning objectives, key terms, examples and cases, and review questions. Instructor Resources: Instructor's Manual, Slides in PowerPoint format, Test Bank Each new print copy includes Navigate 2 Advantage Access that unlocks a comprehensive and interactive eBook, student practice activities and assessments, and for instructors: a full suite of teaching tools, and learning analytics reporting.

Drug Repositioning

Author: Joel Dudley
Publisher: CRC Press
ISBN: 131535621X
Size: 52.41 MB
Format: PDF, Kindle
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Nervous system diseases represent a major health concern worldwide. Although important financial and professional investment, their etiology and pathophysiology still remain mostly elusive. Moreover, the clinical need of disease-modifying therapies is still unmet. In the last decades, traditional R&D has failed in identifying new effective therapies in many medical areas and drug repositioning has recently emerged as a promising alternative strategy to de novo drug discovery to improve and accelerate therapeutic development. For the first time, Drug Repositioning: Approaches and Applications for Neurotherapeutics reviews history and advances in drug repositioning, with a special focus on therapeutics for nervous system diseases. International experts from Academia, Industry and Non-profit organisations will provide different views on drug repositioning advantages, challenges and specific applications, which will be covered for nervous system diseases including Alzheimer's, Parkinson's, Huntington's diseases, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, ischemic stroke, and psychiatric disorders. This book provides a balanced overview and synthesis of drug repositioning concept, methods and applications for neurotherapeutics. It represents a valuable resource for students, scientists and clinicians working in academic settings, industry and government agencies within the fields of neuroscience, pharmacology, neurology, pharmaceutical sciences, drug discovery and development.

The Oxford Handbook Of The Economics Of The Biopharmaceutical Industry

Author: Patricia M. Danzon
Publisher: Oxford University Press
ISBN: 0199909261
Size: 63.35 MB
Format: PDF, Kindle
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The biopharmaceutical industry has been a major driver of technological change in health care, producing unprecedented benefits for patients, cost challenges for payers, and profits for shareholders. As consumers and companies benefit from access to new drugs, policymakers around the globe seek mechanisms to control prices and expenditures commensurate with value. More recently the 1990s productivity boom of new products has turned into a productivity bust, with fewer and more modest innovations, and flat or declining revenues for innovative firms as generics replace their former blockbuster products. This timely volume examines the economics of the biopharmaceutical industry, with eighteen chapters by leading academic health economists. Part one examines the economics of biopharmaceutical innovation including determinants of the costs and returns to new drug development; how capital markets finance R&D and how costs of financing the biopharmaceutical industry compare to financing costs for other industries; the effects of safety and efficacy regulation by the Food and Drug Administration (FDA) and of price and reimbursement regulation on incentives for innovation; and the role of patents and regulatory exclusivities. Part two examines the market for biopharmaceuticals with chapters on prices and reimbursement in the US, the EU, and other industrialized countries, and in developing countries. It looks at the optimal design of insurance for drugs and the effects of cost sharing on spending and on health outcomes; how to measure the value of pharmaceuticals using pharmacoeconomics, including theory, practical challenges, and policy issues; how to measure pharmaceutical price growth over time and recent evidence; empirical evidence on the value of pharmaceuticals in terms of health outcomes; promotion of pharmaceuticals to physicians and consumers; the economics of vaccines; and a review of the evidence on effects of mergers, acquisitions and alliances. Each chapter summarizes the latest insights from theory and recent empirical evidence, and outlines important unanswered questions and areas for future research. Based on solid economics, it is nevertheless written in terms accessible to the general reader. The book is thus recommended reading for academic economists and non-economists, and for those in industry and policy who wish to understand the economics of this fascinating industry.

Principles Of Pharmacoeconomics

Author: J. Lyle Bootman
Publisher: Harvey Whitney Books
ISBN: 9780929375274
Size: 64.11 MB
Format: PDF, Mobi
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Presents various techniques, tools, and strategies to evaluate the economic contribution of specific drug therapies at a policy level and for individual patient needs. "This is a reference without shortcomings. I recommend this highly informative, practical, well-referenced book to students and practitioners."

Research Methods For Pharmaceutical Practice And Policy

Author: Rajender R. Aparasu
Publisher: Pharmaceutical Press
ISBN: 0853698805
Size: 51.13 MB
Format: PDF, Mobi
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This text provides the theory and practice for conducting pharmaceutical policy research. It covers all aspects of scientific research from conceptualising to statistical analysis. It also provides scientific basis and a good understanding of the principles and practice of conducting pharmaceutical policy research.--[Source inconnue].