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Phylogenetic Trees Made Easy

Author: Barry G. Hall
Publisher: Sinauer Associates Incorporated
ISBN: 9780878936069
Size: 35.20 MB
Format: PDF, ePub
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Barry G. Hall helps beginners get started in creating phylogenetic trees from protein or nucleic acid sequence data.

Tree Thinking

Author: David A. Baum
Publisher: Roberts & Company
ISBN: 9781936221165
Size: 38.54 MB
Format: PDF, ePub, Mobi
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Baum and Smith, both professors evolutionary biology and researchers in the field of systematics, present this highly accessible introduction to phylogenetics and its importance in modern biology. Ever since Darwin, the evolutionary histories of organisms have been portrayed in the form of branching trees or "phylogenies." However, the broad significance of the phylogenetic trees has come to be appreciated only quite recently. Phylogenetics has myriad applications in biology, from discovering the features present in ancestral organisms, to finding the sources of invasive species and infectious diseases, to identifying our closest living (and extinct) hominid relatives. Taking a conceptual approach, Tree Thinking introduces readers to the interpretation of phylogenetic trees, how these trees can be reconstructed, and how they can be used to answer biological questions. Examples and vivid metaphors are incorporated throughout, and each chapter concludes with a set of problems, valuable for both students and teachers. Tree Thinking is must-have textbook for any student seeking a solid foundation in this fundamental area of evolutionary biology.

Inferring Phylogenies

Author: Joseph Felsenstein
Publisher: Sinauer Associates Incorporated
ISBN: 9780878931774
Size: 55.30 MB
Format: PDF
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Phylogenies, or evolutionary trees, are the basic structures necessary to think about and analyze differences between species. Statistical, computational, and algorithmic work in this field has been ongoing for four decades now, and there have been great advances in understanding. Yet no book has summarized this work. Inferring Phylogenies does just that in a single, compact volume. Phylogenies are inferred with various kinds of data. This book concentrates on some of the central ones: discretely coded characters, molecular sequences, gene frequencies, and quantitative traits. Also covered are restriction sites, RAPDs, and microsatellites.

The Phylogenetic Handbook

Author: Philippe Lemey
Publisher: Cambridge University Press
ISBN: 0521877105
Size: 56.61 MB
Format: PDF, ePub
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A broad, hands on guide with detailed explanations of current methodology, relevant exercises and popular software tools.

Reading The Story In Dna

Author: Lindell Bromham
Publisher: Oxford University Press on Demand
ISBN:
Size: 23.33 MB
Format: PDF, ePub, Docs
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The world is full of DNA. The salad in your sandwich, the pollen in the air, even the dirt on your shoes contains DNA from which a vast amount of information can be gained, including the identification of individuals and species, the structure and distribution of populations, the origins oflineages and the pace and mechanisms of evolutionary change. Reading the story in DNA is a beginner's guide to molecular evolution, and is the perfect companion on the journey to a proper understanding of molecular data. The central theme of the book is that in order to get ecological or evolutionary information out of molecular data, you must understand the way that the molecular data evolves and the influence that the assumptions you make have on the answers you get. The book blends beautifully clear explanations with cutting-edge examples from the research literature, drawing on the fields of biodiversity, conservation biology, epidemiology, phylogeography, evolutionary development and ancient DNA to explore topics such as molecular evolutionary theory,phylogenetics, molecular clocks, detecting selection and recombination, and identifying individuals from molecular data.Technical detail is set apart from the main text, allowing the student to approach the material in different ways: read only the text and skip the finer details, use the text to understand the technical details or vice versa, or identify key case studies and read the concepts and methods particularto that case. The use of "bioinformatic" analyses has revolutionized biology, and there are now few areas of evolution and ecology that remain untouched by molecular data. Today's biology students and researchers need to be familiar with the application of molecular data to answering evolutionary questions. Butthe most pressing question is usually: "Where do I start?!" This book is the answer.Online Resource Centre:The Online Resource Centre features:- Figures from the book in electronic format, ready to download- Discussion questions and tutorial exercisesFor students:- Annotated weblinks- Topical updates: links to relevant journal articles and websites that describe advancements in the field since the book's publication

Rna Methodologies

Author: Robert E. Farrell, Jr.
Publisher: Academic Press
ISBN: 0128046791
Size: 53.78 MB
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RNA Methodologies, Fifth Edition continues its tradition of excellence in providing the most up-to-date ribonucleic acid lab techniques for seasoned scientists and graduate students alike. This edition features new material on the exploding field of microRNA as well as the methods for the profiling of gene expression, both which have changed considerably in recent years. As a leader in the field, Dr. Farrell provides a wealth of knowledge on the topic of RNA while also giving readers helpful hints from his own personal experience in this subject area. Beginning with the most contemporary, RNA Methodologies, Fifth Edition, presents the essential techniques to use when working with RNA for the experienced practitioner while at the same time providing images and examples to aid the beginner in fully understanding this important branch of molecular biology. The next generation of scientists can look to this work as a guide for ensuring high productivity and highly representative data, as well as best practices in troubleshooting laboratory problems when they arise. Features new material in miRNA, MIQE guidelines, biomarkers, RNA sequencing, digital PCR and more Includes expanded coverage on quantitative PCR techniques, RNAi, bioinformatics, the role of locked nucleic acids, aptamer biology, PCR arrays, and other modern technologies Presents comprehensive, cutting-edge information covering all aspects of working with RNA Builds from basic information on RNA techniques to in-depth protocols to guidance on how to modify and adjust each step of a particular application Presents multiple avenues for addressing the same experimental goals

Molecular Evolution And Phylogenetics

Author: Masatoshi Nei
Publisher: Oxford University Press
ISBN: 0199881227
Size: 74.86 MB
Format: PDF, Docs
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During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

Manual Of Clinical Microbiology

Author: James Versalovic
Publisher: American Society for Microbiology Press
ISBN: 1555814638
Size: 40.83 MB
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The most authoritative, comprehensive reference in the field. • Sets the standard for state-of-the-science laboratory practice. • A collaborative effort of 22 editors and more than 260 authors from around the world, all experienced researchers and practitioners in medical and diagnostic microbiology. • Includes 149 chapters of the latest research findings, infectious agents, methods, practices, and safety guidelines. • Indispensable to clinical microbiologists, laboratory technologists, and infectious disease specialists in hospitals, clinics, reference laboratories, and more