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Placebo And Pain

Author: Luana Colloca
Publisher: Academic Press
ISBN: 0123979315
Size: 65.11 MB
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The placebo effect continues to fascinate scientists, scholars, and clinicians, resulting in an impressive amount of research, mainly in the field of pain. While recent experimental and clinical studies have unraveled salient aspects of the neurobiological substrates and clinical relevance of pain and placebo analgesia, an authoritative source remained lacking until now. By presenting and integrating a broad range of research, Placebo and Pain enhances readers’ knowledge about placebo and nocebo effects, reexamines the methodology of clinical trials, and improves the therapeutic approaches for patients suffering from pain. Review for Placebo and Pain: “This ambitious book is the first comprehensive and unified presentation of the placebo and nocebo phenomena in the area of pain. Written by the international leading experts in the field, the book provides an accurate up-to-date [work] on placebo and pain dealing with current perspectives and future challenging issues. --Ted Kaptchuk, Associate Professor of Medicine, Harvard Medical School Contains historical aspects of the placebo effect Discusses biological and psychological mechanisms of placebo analgesic responses Reviews implications of the placebo effect for clinical research and pain management Includes methodological and ethical aspects of the placebo effect

Das Prinzip Placebo

Author: Antje Maly-Samiralow
Publisher: Knaur MensSana eBook
ISBN: 3426426455
Size: 61.91 MB
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Gesund durch Zuversicht Placebos sind die Pillen, die nicht wirken? Nur ein Täuschungsmanöver der Ärzte? Mit dieser weitverbreiteten Auffassung räumt Antje Maly-Samiralow radikal auf. Die Journalistin legt mit „Das Prinzip Placebo“ das erste populärwissenschaftliche Faktenbuch vor, das verblüffende Zusammenhänge zwischen der Psyche und der Heilkraft des Körpers aufdeckt. Denn die Wissenschaft beweist: Auch alle, die Placebos einnehmen, können profitieren, wenn ihr Gehirn auf den Heilerfolg konditioniert wird. Was heilt, ist unter anderem die Zuversicht. Und die kann wirkmächtige Placebo-Effekte hervorrufen. Negative Suggestionen hingegen können Nocebo-Effekte entfachen, mit zum Teil verheerenden Folgen für die Gesundheit der Betroffenen. Anhand neuester wissenschaftlicher Erkenntnisse zeigt die Autorin Möglichkeiten auf, wie jeder seine Gesundheit selbst positiv beeinflussen und unnötige Nocebo-Effekte vermeiden kann.

Neuroscience Of Pain Stress And Emotion

Author: Magne Arve Flaten
Publisher: Academic Press
ISBN: 0128006668
Size: 42.12 MB
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Neuroscience of Pain, Stress, and Emotion: Psychological and Clinical Implications presents updated research on stress, pain, and emotion, all key research areas within both basic and clinical neuroscience. Improved research understanding of their interaction is ultimately necessary if clinicians and those working in the field of psychosomatic medicine are to alleviate patient suffering. This volume offers broad coverage of that interaction, with chapters written by major researchers in the field. After reviewing the neuroscience of pain and stress, the contents go on to address the interaction between stress and chronic/acute pain, the role of different emotions in pain, neurobiological mechanisms mediating these various interactions, individual differences in both stress and pain, the role of patient expectations during treatment (placebo and nocebo responses), and how those relate to stress modulation. While there are books on the market which discuss pain, stress, and emotion separately, this volume is the first to tackle their nexus, thus appealing to both researchers and clinicians. Represents the only comprehensive reference detailing the link between pain, stress and emotion, covering the neuroscientific underpinnings, related psychological processes, and clinical implications Compiles, in one place, research which promises to improve the methodology of clinical trials and the use of knowledge of pain-stress-emotion effects in order to reduce patients’ suffering Provides comprehensive chapters authored by global leaders in the field, the broadest, most expert coverage available

Botanical Medicine From Bench To Bedside Cooper Kronenberg

Author: Mary Ann Liebert, Inc-Publishers
Publisher: Bukupedia
Size: 27.46 MB
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CONCLUSIONS The challenges presented in this chapter are very real and complicated by a chaotic marketplace and often disor ga nized research agenda. As revealed throughout history and confi rmed through contemporary research, plants have played an important role in women’s health. However, there remains much work to be done “from bench to bedside.” It is important to identify which botanicals are most effi cacious for a given condition as well as how they compare with conventional treatments in terms of safety, effectiveness, and cost. Pharmacokinetic and pharmacodynamic studies are essential as well as research on safety during pregnancy and lactation. Chaste tree appears to be a viable and safe approach for PMS, especially for women who choose not to take oral contraceptives and for whom lifestyle changes are not enough. Chaste tree may have the potential to address certain types of female infertility, which could be very cost effective if proven clinically effective. For PMS and infertility, the herb will be taken by women of reproductive age— so the question of safety in pregnancy is an extremely important one. If chaste tree can correct latent hyperprolactinemia, this would mean a safer and more tolerable treatment for many women. But before this can be studied, dose- ranging studies in women specifi cally looking at prolactin levels are imperative. And basic science is needed to determine what constituent(s), if any, should be considered for standardization based upon the condition being treated. There is defi nitely a need for more rigorous and creative research in the area of botanicals and women’s health. The researcher studies the effi cacy and mechanism of a given therapy so that broad numbers of patients may potentially benefi t from the treatment. Clinicians working in the fi eld of women’s health are keenly aware that treatments must often be tailored to meet the individual needs of the woman and that there is often not one simple answer. Clinicians and researchers could benefi t greatly from more extensive dialogue with each other— so that each can share their unique experiences and worldviews, learning from each other to improve both research and clinical care. For in spite of the lack of rigorous research for many botanicals, it is highly likely that many women will continue to seek out these therapies as a means of self- treatment and self- care. REFERENCES 1Upchurch DM, Chyu L, Greendale GA, Utts J, Bair YA, Zhang G, Gold EB. Complementary and alternative medicine use among American women: fi ndings from the National Health Interview Survey, 2002. J Womens Health (Larchmt). 2007;16:102– 113. 2Vickers K, Jolly KB, Greenfi eld SM. Herbal medicine: women’s views, knowledge and interaction with doctors: a qualitative study. BMC Complement Altern Med. 2006;6:40. 3American College of Obstetrics and Gynecol ogy: Committee opinion. Int J Gynecol Obstet. 1995:50:80. 4Blumenthal M, Goldberg A, Brinckmann J, eds. Herbal Medicine. Expanded Commission E Monographs. Integrative Medicine, Communications. 1st ed. Newton, MA: Integrative Medicine Communications; 2000. 5Webster DE, Lu J, Chen SN, Farnsworth NR, Wang ZJ. Activation of the mu- opiate receptor by Vitex agnus- castus methanol extracts: implication for its use in PMS. J Ethnopharmacol. 2006 Jun 30;106(2): 216– 221.

Pain Assessment And Pharmacologic Management E Book

Author: Chris Pasero
Publisher: Elsevier Health Sciences
ISBN: 0323082637
Size: 61.33 MB
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Pain Assessment and Pharmacologic Management, by highly renowned authors Chris Pasero and Margo McCaffery, is destined to become the definitive resource in pain management in adults. It provides numerous reproducible tables, boxes, and figures that can be used in clinical practice, and emphasizes the benefits of a multimodal analgesic approach throughout. In addition, Patient Medication Information forms for the most commonly used medications in each analgesic group can be copied and given to patients. This title is an excellent resource for nurses to become certified in pain management. Presents best practices and evidence-based guidelines for assessing and managing pain most effectively with the latest medications and drug regimens. Features detailed, step-by-step guidance on effective pain assessment to help nurses appropriately evaluate pain for each patient during routine assessments. Provides reproducible tables, boxes, and figures that can be used in clinical practice. Contains Patient Medication Information forms for the most commonly used medications in each analgesic group, to be copied and given to patients. Offers the authors' world-renowned expertise in five sections: Underlying Mechanisms of Pain and the Pathophysiology of Neuropathic Pain includes figures that clearly illustrate nociception and classification of pain by inferred pathology. Assessment includes tools to assess patients who can report their pain as well as those who are nonverbal, such as the cognitively impaired and critically ill patients. Several pain-rating scales are translated in over 20 languages. Nonnopioids includes indications for using acetaminophen or NSAIDs, and the prevention and treatment of adverse effects. Opioids includes guidelines for opioid drug selection and routes of administration, and the prevention and treatment of adverse effects. Adjuvant Analgesics presents different types of adjuvant analgesics for a variety of pain types, including persistent (chronic) pain, acute pain, neuropathic pain, and bone pain. Prevention and treatment of adverse effects is also covered. Includes helpful Appendices that provide website resources and suggestions for the use of opioid agreements and for incorporating pain documentation into the electronic medical record. Covers patients from young adults to frail older adults. Provides evidence-based, practical guidance on planning and implementing pain management in accordance with current TJC guidelines and best practices. Includes illustrations to clarify concepts and processes such as the mechanisms of action for pain medications. Features spiral binding to facilitate quick reference.

The Handbook Of Cannabis Therapeutics

Author: Ethan B. Russo
Publisher: Routledge
ISBN: 1136752854
Size: 19.51 MB
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Learn the facts behind the pharmacology and pharmacokinetics of controversial cannabis therapeutics The Handbook of Cannabis Therapeutics: From Bench to Bedside sets aside the condemnation and hysteria of society’s view of cannabis to concentrate on the medically sound aspects of cannabis therapeutics. The world’s foremost experts provide a reasoned, thoroughly researched overview of the controversial subject of cannabis, from its history as a medicine through its latest therapeutic uses. The latest studies on the botany, history, biochemistry, pharmacology, toxicology, clinical use for various illnesses such as AIDS, epilepsy, and multiple sclerosis, and side effects of marijuana are all examined and discussed in depth. This comprehensive resource is a compendium of articles from the Journal of Cannabis Therapeutics—with additional contemporary commentary. It presents startling research that explores and supports the medicinal value of cannabis use and its derivatives as a valid therapeutic resource for pain and inflammation, for several illnesses less responsive to other therapies, and even for certain veterinary uses. Cannabinoids such as nabilone, THC, levonantradol, ajulemic acid, dexanabinal, and others are extensively described, with a review of new indications for cannabinoid pharmaceuticals. The book is carefully referenced to encourage your examination of previous studies and provides tables and figures to enhance understanding of information. The Handbook of Cannabis Therapeutics discusses: the uses of cannabis in Arabic, Greek, Roman, and early English medicines absorption rates pharmacokinetics pharmacodynamics separate extracts versus the use of cannabis in its entirety the therapeutic value of the endocannabinoid system cannabinoids and newborn feeding a comparison of smoking versus oral preparations clinical research data on eating cannabis therapeutic uses as appetite stimulant treatments in obstetrics and gynecology medicinal treatments used in Jamaica the use of cannabis in the treatment of multiple sclerosis the benefits versus the adverse side effects of cannabis use The Handbook of Cannabis Therapeutics is a reference work certain to become crucial to physicians, psychologists, researchers, biochemists, graduate students, and interested members of the public.

Botanical Medicine

Author: Raymond Cooper
Size: 15.45 MB
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"Based loosely on the workshop Clinical Pharmacognosy: Contribution of Pharmacognosy to Clinical Trials of Botanicals and Dietary Supplements, held at the American Society of Pharmacognosy (ASP) meeting in Portland, Maine"--P. [xi].

Tscherne Unfallchirurgie

Author: Harald Tscherne
Publisher: Springer-Verlag
ISBN: 3642592155
Size: 40.40 MB
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o Das Thema Das Polytrauma stellt eine der größten Herausforderungen in der Unfallchirurgie dar und verlangt nach einem optimalen Zusammenspiel aller an der Versorgung beteiligten Kräfte. Konsequentes Management des traumatisierten Patienten erfordert konkrete Richtlinien für die Praxis. o Das Spektrum In den drei Hauptteilen Infrastruktur, Präklinik und Klinik werden alle Aspekte des Trauma-Managements kompetent abgehandelt. Anhand erprobter und bewährter Modelle wird das erforderliche Höchstmaß an Infrastruktur, Logistik, Ausbildung und Training ebenso souverän präsentiert wie das diagnostische und therapeutische Spektrum. Standardisierte Handlungskonzepte vermitteln die in der Akutsituation notwendige Sicherheit und Routine. o Die Herausgeber Prof. Dr. Harald Tscherne ist Ärztlicher Direktor der Unfallchirurgischen Klinik der MHH. Prof. Dr. Gerd Regel ist Oberarzt an der Unfallchirurgischen Klinik der MHH.

Arzneitherapie F R Ltere

Author: Martin Wehling
Publisher: Springer-Verlag
ISBN: 366248126X
Size: 52.72 MB
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Dieses Buch bietet sichere Arzneitherapie für ältere Patienten und wendet sich mit den folgenden Fragestellungen an die Fachärzte. Welche Besonderheiten es bei älteren Patienten gibt Welche Nebenwirkungen/Wechselwirkungeninsbesondere beachtet werden müssen und ggfs. als neue eigenständige Erkrankungen fehlinterpretiert werden können Welche Arzneimittel für ältere Patienten ungeeignet sind bzw. besondere Vorsicht erfordern Menschen im Alter über 65 Jahre bilden die am stärksten wachsende Bevölkerungsgruppe. Ältere Patienten haben häufig mehrere - oft chronische – Erkrankungen. Unerwünschte Arzneimittelwirkungen sind überdurchschnittlich häufig u.a. wegen: geänderter biologischer Eckdaten (Leberdurchblutung und Nierenfunktion vermindert, mehr Fett- weniger Muskelmasse) mangelnder Compliance Vielfachmedikation mit kaum vorhersagbaren Wechselwirkungen NEU Neueste Daten, Statistiken, Key Evidences Wertungssystem für Alterstauglichkeit von Arzneimitteln nach FORTA-Liste (top-aktuell nach 2. Delphi-Prozess 2015) Neue Inhalte, u.a. Suchterkrankungen Wechselwirkungen von Medikamenten mit Lebensmitteln (z.B. Grapefruit) oder mit pflanzlichen Arzneimitteln (z.B. Johanniskrautpräparate). Choosing wisely Die Lösungsvorschläge und Antworten für die tägliche Praxis: Medizinische Sicherheit: Welche Medikamente haben Priorität? Was kann/muss ich weglassen? Ökonomische Sicherheit: Bessere Arzneitherapie mit weniger Verschreibungen (= Einhaltung des Arzneimittelbudgets).

Neuroreha Nach Schlaganfall

Author: Jan Mehrholz
Publisher: Georg Thieme Verlag
ISBN: 3131654910
Size: 53.40 MB
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Die ganze Komplexität der Schlaganfallrehabilitation - Allle Facetten der Rehabilitation verstehen und effektiv in die Behandlung integrieren - Von internationalen Experten gut verständlich aufbereitet - Zum Selbststudium und für die tägliche Arbeit am Patienten - Didaktische Elemente erleichtern das Begreifen: Lernziele zu Beginn und Zusammenfassungen am Ende jedes Kapitels