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Quantum Magnetic Resonance Imaging Diagnostics Of Human Brain Disorders

Author: Madan M Kaila
Publisher: Elsevier
ISBN: 9780123847126
Size: 51.74 MB
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Magnetic resonance imaging (MRI) is a medical imaging technique used to visualize detailed internal structure of the body. This book discusses the recent developments in the field of MRI and its application to the diagnosis of human brain disorders. In addition, it reviews the newly emerging concepts and technology, based on the multi-coherence imaging (MQCI). It explains how computer packages can be used to generate images in diseased states and compare them to in vivo results. This will help improve the diagnosis of brain disorders based on the real-time events happening on atomic and molecular quantum levels. This is important since quantum-based MRI would enable clinicians to detect brain tumors at the very early stages. Uses practical examples to explain the techniques - making it easier to understand the concepts Uses diagrams to explain the physics behind the technique - avoiding the use of complicated mathematical formulae

Bio Nanoimaging

Author: Vladimir Uversky
Publisher: Academic Press
ISBN: 0123978211
Size: 66.49 MB
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Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties. Provides practical examples of nanoimaging research from leading molecular biology, cell biology, protein chemistry, biotechnology, genetics, and pharmaceutical labs Includes over 200 color images to illustrate the power of various nanoimaging technologies Focuses on nanoimaging techniques applied to protein misfolding and aggregation in molecular medicine

Fundamental Neuroscience

Author: Larry R. Squire
Publisher: Academic Press
ISBN: 0123858704
Size: 16.27 MB
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Fundamental Neuroscience, 3rd Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts. A companion web site contains test questions, and an imagebank of the figures for ready use in presentations, slides, and handouts. Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! New to this edition: * 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness * Companion website with figures, web links to additional material, and test questions * Additional text boxes describing key experiments, disorders, methods, and concepts * Multiple model system coverage beyond rats, mice, and monkeys * Extensively expanded index for easier referencing

Comprehensive Biomedical Physics

Author:
Publisher: Newnes
ISBN: 0444536337
Size: 57.72 MB
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Comprehensive Biomedical Physics is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color

Molecular Neurology

Author: Stephen Waxman
Publisher: Elsevier
ISBN: 9780080546186
Size: 67.77 MB
Format: PDF
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Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology. Describes the newest molecular aspects of neurological disorders Provides an introduction to neurological disorders for basic scientists Updates clinicians and clinical researchers on the most recent developments

Equine Mri

Author: Rachel C. Murray
Publisher: John Wiley & Sons
ISBN: 9781444329209
Size: 68.95 MB
Format: PDF
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Equine MRI is a unique, comprehensive guide to MRI in the horse. Edited by Rachel Murray, a leading authority and researcher in the field with over ten years of equine clinical MRI experience, the book also includes contributions from worldwide experts in the subject. Divided into the following four sections, the book presents key information based on previous validation work and clinical practice: Principles of MRI, including the practicalities of image acquisition and interpretation Normal MRI anatomy and normal variations Different types of pathological change Options for clinical management and prognosis for different conditions MRI is a rapidly expanding area in veterinary medicine that confers detailed, three-dimensional information on both bone and soft tissue. Expanding clinical knowledge, improvements in technology, and practical application of MRI to the standing and recumbent horse means this useful imaging modality has become an integral and essential part of the diagnostic evaluation in lameness and is a realistic option for investigation of ophthalmological, neurological and cranial pathology. Equine MRI enables readers to understand the best ways to achieve good quality images, and provides a detailed explanation of the problems that may occur. With close to 950 normal and abnormal images, this book offers considerable detail and examples of both common and uncommon problems, making it a great reference for equine veterinarians, veterinary students, specialists in equine surgery, and specialists in veterinary imaging.

Guide To Research Techniques In Neuroscience

Author: Matt Carter
Publisher: Academic Press
ISBN: 9780080951744
Size: 61.67 MB
Format: PDF, Docs
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Neuroscience is by definition a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry. A single topic such as the auditory system can be studied using techniques from genetics, imaging, biochemistry, or electrophysiology. A young scientist must learn how to read the primary literature and then develop their own experiments. This book offers that scientist an overview of mainstream research techniques, provides guidelines on how to choose one technique over another, offers tips on analyzing data, and provides a list of references for additional detailed study. This book can also assist an experienced scientist understand published studies conducted outside their own subfield. *Written by Stanford University graduate students in neuroscience to provide a "hands-on" approach for other neuroscience graduate students *Techniques within one field will be compared so that user can select best technique for their experiment *Chapters include references (key articles, books, protocols) for additional detailed study *Data Analysis boxes in each chapter help with data interpretation and offer guidelines on how best to represent results *"Walk-through" boxes guide students through the experiment step-by-step

Principles Of Magnetic Resonance Imaging

Author: Zhi-Pei Liang
Publisher: Wiley-IEEE Press
ISBN: 9780780347236
Size: 50.84 MB
Format: PDF
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In 1971 Dr. Paul C. Lauterbur pioneered spatial information encoding principles that made image formation possible by using magnetic resonance signals. Now Lauterbur, "father of the MRI", and Dr. Zhi-Pei Liang have co-authored the first engineering textbook on magnetic resonance imaging. This long-awaited, definitive text will help undergraduate and graduate students of biomedical engineering, biomedical imaging scientists, radiologists, and electrical engineers gain an in-depth understanding of MRI principles. The authors use a signal processing approach to describe the fundamentals of magnetic resonance imaging. You will find a clear and rigorous discussion of these carefully selected essential topics: Mathematical fundamentals Signal generation and detection principles Signal characteristics Signal localization principles Image reconstruction techniques Image contrast mechanisms Image resolution, noise, and artifacts Fast-scan imaging Constrained reconstruction Complete with a comprehensive set of examples and homework problems, Principles of Magnetic Resonance Imaging is the must-read book to improve your knowledge of this revolutionary technique.

Handbook Of Psychophysiology

Author: John T. Cacioppo
Publisher: Cambridge University Press
ISBN: 1316727785
Size: 67.88 MB
Format: PDF, ePub, Mobi
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The Handbook of Psychophysiology has been the authoritative resource for more than a quarter of a century. Since the third edition was published a decade ago, the field of psychophysiological science has seen significant advances, both in traditional measures such as electroencephalography, event-related brain potentials, and cardiovascular assessments, and in novel approaches and methods in behavioural epigenetics, neuroimaging, psychoneuroimmunology, psychoneuroendocrinology, neuropsychology, behavioural genetics, connectivity analyses, and non-contact sensors. At the same time, a thoroughgoing interdisciplinary focus has emerged as essential to scientific progress. Emphasizing the need for multiple measures, careful experimental design, and logical inference, the fourth edition of the Handbook provides updated and expanded coverage of approaches, methods, and analyses in the field. With state-of-the-art reviews of research in topical areas such as stress, emotion, development, language, psychopathology, and behavioural medicine, the Handbook remains the essential reference for students and scientists in the behavioural, cognitive, and biological sciences.

Magnetic Resonance And Its Applications

Author: Vladimir I. Chizhik
Publisher: Springer Science & Business Media
ISBN: 3319052993
Size: 56.64 MB
Format: PDF
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The book is devoted to the description of the fundamentals in the area of magnetic resonance. The book covers two domains: radiospectroscopy and quantum radioelectronics. Radiospectroscopy comprises nuclear magnetic resonance , electron paramagnetic resonance, nuclear quadrupolar resonance, and some other phenomena. The radiospectroscopic methods are widely used for obtaining the information on internal (nano, micro and macro) structure of objects. Quantum radioelectronics, which was developed on the basis of radiospectroscopic methods, deals with processes in quantum amplifiers, generators and magnetometers. We do not know analogues of the book presented. The book implies a few levels of the general consideration of phenomena, that can be useful for different groups of readers (students, PhD students, scientists from other scientific branches: physics, chemistry, physical chemistry, biochemistry, biology and medicine).