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Reeds Splicing Handbook

Author: Jan-Willem Polman
Publisher: Bloomsbury Publishing
ISBN: 1472952774
Size: 14.35 MB
Format: PDF
View: 523
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For any seafarer, splicing rope is an essential skill. But the traditional 3-strand rope is fast disappearing. So how do you splice braided rope? This is the definitive pocket-sized guide to all rope splicing techniques. Most of the techniques are quite easy to master – and also fun to do. See why splices are better – and stronger – than knots or shackles for joining or shortening rope, and follow the step-by-step photographs and clear instructions to find out how to splice efficiently. Containing step by step photos and clear instructions, this colourful and easy to follow aide memoire guides users every step of the way.

Reeds Knot Handbook

Author: Jim Whippy
Publisher: A&C Black
ISBN: 1408139529
Size: 45.11 MB
Format: PDF, ePub
View: 5253
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Part of the bestselling Reeds Skipper's Handbook series, this handy pocket guide presents the most useful knots and splices for onboard (and dockside) use. Each knot will have a double page spread with step by step photos plus a tying diagram, accompanied by carefully explained instructions on how to tie the knot plus its most appropriate uses (for example - is it strong enough not to stretch or slip? Will it untie quickly in an emergency? Can it be tied with all thicknesses and types of rope?) All boaters need a repertoire of reliable knots they can use almost without thinking about them - this book will act as a quick aide memoire, as well as providing novices with all the steps they need to master the most useful knots they will need on a regular basis when going to sea.

Handbook Of Anticancer Pharmacokinetics And Pharmacodynamics

Author: Michelle A. Rudek
Publisher: Springer Science & Business Media
ISBN: 1461491355
Size: 25.32 MB
Format: PDF, Docs
View: 2083
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There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development

The Caner S Handbook

Author: Bruce W. Miller
Publisher: Lark Books
ISBN: 9780937274606
Size: 62.23 MB
Format: PDF, ePub, Mobi
View: 1896
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To become an expert caner, you need only three things: a few materials, a piece of furniture, and this book. Give life to old cane furniture as well as weaving seats and backs for new pieces. Traditional techniques and new shortcuts make caning with wicker, rattan, raw-hide, and other materials easy. Useful charts detail how much fibre to buy and what standard lengths are available.

Handbook Of Composite Reinforcements

Author: Stuart M. Lee
Publisher: John Wiley & Sons
ISBN: 9780471188612
Size: 31.37 MB
Format: PDF, ePub, Mobi
View: 2825
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This comprehensive single volume handbook covers every aspect ofreinforcement science, from hands-on subjects, such as manual'lay-up' processing, to theoretical discussions concerning rheologyand modeling. Taken from the recently published six volumeInternational Encyclopedia of Composites, this reference volumeoffers scholarly and practical knowledge of distinguishedindustry-experts, academics, and government researchers in oneaccessible and informative handbook. Fibers, processes, and composite reinforcement types, as well asrelevant miscellaneous subjects such as property relationships,manufacturing, hybrid reinforcements, and modeling are givendetailed treatment. Engineers, materials scientists, andtechnologists will find the Composite Reinforcement Handbook aninvaluable tool.

The Splicing Handbook Third Edition

Author: Barbara Merry
Publisher: McGraw Hill Professional
ISBN: 0071736956
Size: 25.68 MB
Format: PDF
View: 485
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The only reference devoted entirely to splicing today’s ropes The Splicing Handbook includes step-by-step illustrations and explanations for the most useful and popular splices in traditional twisted and modern braided ropes, and it covers every kind of splicing project you are likely to encounter, including modern cordage such as Spectra; mainstream rope materials such as Dacron and nylon; and wire and rope-to-wire splices. Covers all the standard rope constructions using Dacron and nylon, including solid braid, double braid, parallel core, plaited, and three-strand Explains how to splice wire for sailboat shrouds and halyards Shows how to make a broad range of useful onboard projects--and several that will find uses around the home as well, including dog collars, netting, rope railings, and lanyards.