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Rodent Model As Tools In Ethical Biomedical Research

Author: Monica Levy Andersen
Publisher: Springer
ISBN: 3319115782
Size: 19.20 MB
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​The objective of this book is to concisely present information with respect to appropriate use of experimental rodents in research. The principles elaborated seek to provide knowledge of the techniques involved in both management and scientific research to all who use laboratory animals, with a focus on the well-being and ethics regarding rodents and also to fortify the awareness of the importance of the animal as a study object and to offer orientation and assistance in conducting laboratory research, education or tests.


Author: Chukwuebuka Egbuna
Publisher: CRC Press
ISBN: 0429760329
Size: 66.78 MB
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This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.

Sourcebook Of Models For Biomedical Research

Author: P. Michael Conn
Publisher: Springer Science & Business Media
ISBN: 1588299333
Size: 52.48 MB
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The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.

Animal Models For Human Cancer

Author: Marianne I. Martic-Kehl
Publisher: John Wiley & Sons
ISBN: 3527695915
Size: 50.27 MB
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Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animal studies for improving human therapy and gives recommendations for future drug development.

Lignes Directrices De L Ocde Pour Les Essais De Produits Chimiques Section 4 Essai N 408 Toxicit Orale Doses R P T Es Rongeurs 90 Jours

Author: OECD
Publisher: OECD Publishing
ISBN: 9264070710
Size: 46.38 MB
Format: PDF
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Cette méthode fournit des informations sur les dangers pour la santé qui peuvent résulter d’une exposition à une substance d’essai par voie orale. La détermination d’une toxicité sub-chronique orale utilisant des doses répétées peut être effectuée ...

Human Embryonic Stem Cells

Author: Jon Odorico
Publisher: Garland Science
ISBN: 0203487346
Size: 79.32 MB
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Since the first successful isolation and cultivation of human embryonic stem cells at the University of Wisconsin, Madison in 1998, there has been high levels of both interest and controversy in this area of research. This book provides a concise overview of an exciting field, covering the characteristics of both human embryonic stem cells and pluripotent stem cells from other human cell lineages. The following chapters describe state-of-the-art differentiation and characterization of specific ectoderm, mesoderm and endoderm-derived lineages from human embryonic stem cells, emphasizing how these can be used to study human developmental mechanisms. A further chapter discusses genetic manipulation of human ES cells. The concluding section covers therapeutic applications of human ES cells, as well as addressing the ethical and legal issues that this research have raised.

Essentials Of Domestic Animal Embryology E Book

Author: Poul Hyttel
Publisher: Elsevier Health Sciences
ISBN: 0702042595
Size: 25.49 MB
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This reference on veterinary embryology covers general embryology, i.e. the development from the formation of the gametes over fertilization and initial embryogenesis up to the stage where organ formation is initiated, and special embryology, i.e. the development of the organ systems. Moreover, the book also includes a section on teratology, one on assisted reproductive technologies and one on veterinary and societal aspects. Written with the veterinary student in mind, this textbook is written in an accessible style with high quality colour illustrations and line drawings. Succinct and accessible 300 high-quality colour illustrations Written for undergraduates and invaluable for graduates wishing to brush up