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Skeletal Research An Experimental Approach

Author: David J. Simmons
Publisher: Elsevier
ISBN: 0323141595
Size: 52.99 MB
Format: PDF
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Skeletal Research, An Experimental Approach discusses experimental studies on bone cell and tissue biochemistry, biomechanics, isolation, and methods of analysis. Divided into four parts encompassing 21 chapters, this book describes the advantages and limitations of approaches and options available for bone laboratories. The opening part of this book describes the isolation, characterization, and methods of analysis of bone and cartilage cells and their organ cultures. This description is followed by discussions on the intermediary metabolism of growth and articular cartilage; the isolation of plasma membranes from calcified connective tissues; and the aspects of lipidology as it applies to calcified tissue. The third part of this book focuses on the chemical, histochemical, and pathophysiological studies of bone as tissue. This text includes significant chapters on bone’s biomechanics and bioelectricity; bone mineral composition; collagen biochemistry; calcium metabolism; and blood flow. Studies on bone and cartilage as circadian systems in rats and mice, emphasizing the importance of this aspect of experimental design, are covered in the concluding part of this book. This text is an ideal resource to experienced researchers and young investigators who wish to expand their technical knowledge on bone research.

Methods In Bone Biology

Author: T. Arnett
Publisher: Springer Science & Business Media
ISBN: 0585382271
Size: 22.69 MB
Format: PDF, Kindle
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Methods in Bone Biology is unique in being devoted to describing the methodology used by bone researchers. This book describes in detail the techniques of cell and organ culture used in the study of bone and bone cell function and the techniques used to monitor the skeleton and skeletal remodelling both in clinical and experimental settings.

Research Surgery And Care Of The Research Animal

Author: William I. Gay
Publisher: Elsevier
ISBN: 1483259544
Size: 77.15 MB
Format: PDF, ePub
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Methods of Animal Experimentation, Volume VII: Research Surgery and Care of the Research Animal, Part B is a collection of papers that deals with methods used in animal experiments concerning surgical approaches to certain organ systems. This collection deals with surgery involving the respiratory, cardiovascular, skeletal, gastrointestinal, genital, and central nervous systems of the test animals. One paper describes the procedures to be followed in thoracic incisions, emphasizing the importance of access to airways and parenchymal resections. In explaining cardiovascular surgery, one paper details the specialized surgical equipment, anesthesia, blood flow, and post-operative care that the test animal needs. Another paper describes the procedures and techniques, as well as limb immobilization or total joint prostheses that should be followed in a surgery involving the skeletal system. One author also considers in detail both research surgeries of the male and female reproductive tracts. The paper on surgery involving the peripheral and central nervous system gives general techniques used in chronic studies of such system. Veterinarians, laboratory workers dealing with test animals, and researchers designing animal and medical experiments will find this book very informative.

Bones

Author: P. D. F. Murray
Publisher: CUP Archive
ISBN: 9780521315494
Size: 78.14 MB
Format: PDF
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Bones was originally published in 1936 and is still essential reading for anyone entering bone research. A classic in the field of skeletal development, biology, anatomy and anthropology, the book sets out in clear and lucid prose the experimental basis for our current notions on how intrinsic and extrinsic (largely mechanical) factors interact in initiating differentiation of cartilage and bone, in shaping the skeleton and in regulating its growth. It established the skeleton as a dynamic, responsive system of tissues, not just inert bones. The present edition, in the Cambridge Science Classics Series, includes an introductory essay by Professor B.K. Hall, who was the last of Professor Murray's Ph.D. students and who is himself distinguished for his work in the area. Brian Hall provides an overview of research during the half-century since Bones was first published, on major topics covered in the book - the origin of skeletal cells, cartilage morphogenesis, the formation of joints, the trajectory theory and bone structure, growth of cartilage and bone.

Research Methods In Human Skeletal Biology

Author: Elizabeth A. DiGangi
Publisher: Academic Press
ISBN: 0123851890
Size: 34.72 MB
Format: PDF, Kindle
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Research Methods in Human Skeletal Biology serves as the one location readers can go to not only learn how to conduct research in general, but how research is specifically conducted within human skeletal biology. It outlines the current types of research being conducted within each sub-specialty of skeletal biology, and gives the reader the tools to set up a research project in skeletal biology. It also suggests several ideas for potential projects. Each chapter has an inclusive bibliography, which can serve as a good jumpstart for project references. Provides a step-by-step guide to conducting research in human skeletal biology Covers diverse topics (sexing, aging, stature and ancestry estimation) and new technologies (histology, medical imaging, and geometric morphometrics) Excellent accompaniment to existing forensic anthropology or osteology works

Experimental Methods In Orthopaedic Biomechanics

Author: Radovan Zdero
Publisher: Academic Press
ISBN: 0128038551
Size: 80.33 MB
Format: PDF
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Experimental Methods in Orthopaedic Biomechanics is the first book in the field that focuses on the practicalities of performing a large variety of in-vitro laboratory experiments. Explanations are thorough, informative, and feature standard lab equipment to enable biomedical engineers to advance from a ‘trial and error’ approach to an efficient system recommended by experienced leaders. This is an ideal tool for biomedical engineers or biomechanics professors in their teaching, as well as for those studying and carrying out lab assignments and projects in the field. The experienced authors have established a standard that researchers can test against in order to explain the strengths and weaknesses of testing approaches. Provides step-by-step guidance to help with in-vitro experiments in orthopaedic biomechanics Presents a DIY manual that is fully equipped with illustrations, practical tips, quiz questions, and much more Includes input from field experts who combine their real-world experience to provide invaluable insights for all those in the field

Bone Substitute Biomaterials

Author: K. Mallick
Publisher: Elsevier
ISBN: 0857099035
Size: 23.65 MB
Format: PDF, Mobi
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Bone substitute biomaterials are fundamental to the biomedical sector, and have recently benefitted from extensive research and technological advances aimed at minimizing failure rates and reducing the need for further surgery. This book reviews these developments, with a particular focus on the desirable properties for bone substitute materials and their potential to encourage bone repair and regeneration. Part I covers the principles of bone substitute biomaterials for medical applications. One chapter reviews the quantification of bone mechanics at the whole-bone, micro-scale, and non-scale levels, while others discuss biomineralization, osteoductivization, materials to fill bone defects, and bioresorbable materials. Part II focuses on biomaterials as scaffolds and implants, including multi-functional scaffolds, bioceramics, and titanium-based foams. Finally, Part III reviews further materials with the potential to encourage bone repair and regeneration, including cartilage grafts, chitosan, inorganic polymer composites, and marine organisms. Provides a detailed and accurate overview of the bone substitute biomaterials, a fundamental part of the biomaterials and biomedical sector Provides readers with the principles of bone substitute biomaterials Reviews biomaterials for bone regeneration