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Stress And Environmental Regulation Of Gene Expression And Adaptation In Bacteria 2 Volume Set

Author: Frans J. de Bruijn
Publisher: John Wiley & Sons
ISBN: 1119004888
Size: 15.47 MB
Format: PDF, ePub
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Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.

Environmental Stressors And Gene Responses

Author: J.M. Storey
Publisher: Elsevier
ISBN: 9780080531120
Size: 49.57 MB
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Cell and Molecular Responses to Stress is a new multi-volume book series from Elsevier Science that focuses on how organisms respond at a molecular level to environmental stresses imposed upon them. All organisms deal with variations in multiple environmental factors including temperature, oxygen, salinity, and water availability. Many show amazing tolerances to extreme stress with remarkable biochemical adaptations that allow life to persist under very difficult circumstances. This series explores the molecular mechanisms by which cells and organisms respond to stress, focusing on the variations in metabolic response that allow some cells and organisms to deal with extreme stress, others to endure stress within strict limits, and others to have a very low tolerance for changes in environmental parameters. Articles from within the series highlight the elastic limits of molecular responses in Nature, with examples drawn from animal, plant and bacteria systems. Volume 1, begins by considering some of the roles of environmental stress in determining the geographic distribution of animals and in promoting species divergence and then explores gene expression and metabolic responses to environmental stress with examples of adaptation to high and low temperature, osmotic, anoxia/ischemia, desiccation, high pressure and heavy metal stresses.

Principles And Practice Of Infectious Diseases

Author: John E. Bennett
Publisher: Elsevier Health Sciences
ISBN: 1455748013
Size: 51.26 MB
Format: PDF, ePub
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After thirty five years, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. "I highly recommend Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, together with the included ExpertConsult, the on-line version of the book that is a searchable source and is available to a variety of platforms. It is updated twice each year and is an excellent solution for health-care professionals to keep informed of the latest knowledge" Reviewed by Graefes Arch Clin Exp Ophthalmol, March 2015 "..what an in depth textbook should be, a superb and vast, yet highly readable review of its topic." Reviewed by glycosmedia.com, Mar 2015 "Principles and Practice of Infectious Diseases has many features and formats that make it a comprehensive, current, and clear source of information" Reviewed by Graefes Arch Clin Exp Ophthalmol, Feb 2015 Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.

Environmental Adaptations And Stress Tolerance Of Plants In The Era Of Climate Change

Author: Parvaiz Ahmad
Publisher: Springer Science & Business Media
ISBN: 9781461408154
Size: 17.33 MB
Format: PDF
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Climate change is a complex phenomenon with a wide range of impacts on the environment. Biotic and abiotic stress are a result of climate change. Abiotic stress is caused by primary and secondary stresses which are an impediment to plant productivity. Prolonged exposure to these stresses results in altered metabolism and damage to biomolecules. Plants evolve defense mechanisms to withstand these stresses, e.g. synthesis of osmolytes, osmoprotectants, and antioxidants. Stress responsive genes and gene products including expressed proteins are implicated in conferring tolerance to the plant. This volume will provide the reader with a wide spectrum of information, including vital references. It also provides information as to how phytoconstituents, hormones and plant associated microbes help the plants to tolerate the stress. This volume also highlights the use of plant resources for ameliorating soil contaminants such as heavy metals. Dr. Parvaiz is Assistant professor in Botany at A.S. College, Srinagar, Jammu and Kashmir, India. He has completed his post-graduation in Botany in 2000 from Jamia Hamdard New Delhi India. After his Ph.D from the Indian Institute of Technology (IIT) Delhi, India in 2007 he joined the International Centre for Genetic Engineering and Biotechnology, New Delhi. He has published more than 20 research papers in peer reviewed journals and 4 book chapters. He has also edited a volume which is in press with Studium Press Pvt. India Ltd., New Delhi, India. Dr. Parvaiz is actively engaged in studying the molecular and physio-biochemical responses of different plants (mulberry, pea, Indian mustard) under environmental stress. Prof. M.N.V. Prasad is a Professor in the Department of Plant Sciences at the University of Hyderabad, India. He received B.Sc. (1973) and M.Sc. (1975) degrees from Andhra University, India, and the Ph.D. degree (1979) in botany from the University of Lucknow, India. Prasad had published 216 articles in peer reviewed journals and 82 book chapters and conference proceedings in the broad area of environmental botany and heavy metal stress in plants. He is the author, co-author, editor, or co-editor for eight books. He is the recipient of Pitamber Pant national Environment Fellowship of 2007 awarded by the Ministry of Environment and Forests, Government of India.

Plant Responses To Abiotic Stress

Author: Heribert Hirt
Publisher: Springer Science & Business Media
ISBN: 9783540200376
Size: 28.93 MB
Format: PDF, ePub, Docs
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Introduction; Molecular responses of higher plants to dehydration; Abscisic acid signalling; Plant responses to heat stress; Sensors of abiotic stress in Synechocystis; Oxidative stress signalling; Signal transduction in plant cold acclimation; Heavy metal signalling in plants: linking cellular and organismic responses; Molecular genetics of genotoxic stress signalling in plants; Plant salt tolerance; Transcriptome analysis in abiotic stress conditions in higher plants.

C Elegans

Author: Kevin Strange
Publisher: Springer Science & Business Media
ISBN: 1597451517
Size: 67.93 MB
Format: PDF, Mobi
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The goal of C. elegans is to provide overviews and detailed step-by-step descriptions of newer and state-of-the-art methods utilized in the field. These include tools essential for forward and reverse genetic analysis, data mining, and comparative genomics strategies, electron and fluorescence microscopy methods, automated imaging methods for worm behavioral analysis, functional genomics strategies, and methods for physiological analyses including somatic cell culture, toxicity assays, electrophysiology, and in vivo imaging of intracellular Ca2+ and pH using genetically encoded fluorescent indicator proteins.

Plant Acclimation To Environmental Stress

Author: Narendra Tuteja
Publisher: Springer Science & Business Media
ISBN: 1461450012
Size: 18.62 MB
Format: PDF, Mobi
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The mechanisms underlying endurance and adaptation to environmental stress factors in plants have long been the focus of intense research. Plants overcome environmental stresses by development of tolerance, resistance or avoidance mechanisms, adjusting to a gradual change in its environment which allows them to maintain performance across a range of adverse environmental conditions. Plant Acclimation to Environmental Stress presents the latest ideas and trends on induced acclimation of plants to environmental stresses under changing environment. Written by experts around the globe, this volume adds new dimensions in the field of plant acclimation to abiotic stress factors. Comprehensive and lavishly illustrated, Plant Acclimation to Environmental Stress is a state-of-the-art guide suited for scholars and researchers working in the field of crop improvement, genetic engineering and abiotic stress tolerance.