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Testing Statistical Hypotheses Of Equivalence And Noninferiority Second Edition

Author: Stefan Wellek
Publisher: CRC Press
ISBN: 9781439808191
Size: 16.72 MB
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While continuing to focus on methods of testing for two-sided equivalence, Testing Statistical Hypotheses of Equivalence and Noninferiority, Second Edition gives much more attention to noninferiority testing. It covers a spectrum of equivalence testing problems of both types, ranging from a one-sample problem with normally distributed observations of fixed known variance to problems involving several dependent or independent samples and multivariate data. Along with expanding the material on noninferiority problems, this edition includes new chapters on equivalence tests for multivariate data and tests for relevant differences between treatments. A majority of the computer programs offered online are now available not only in SAS or Fortran but also as R scripts or as shared objects that can be called within the R system. This book provides readers with a rich repertoire of efficient solutions to specific equivalence and noninferiority testing problems frequently encountered in the analysis of real data sets. It first presents general approaches to problems of testing for noninferiority and two-sided equivalence. Each subsequent chapter then focuses on a specific procedure and its practical implementation. The last chapter describes basic theoretical results about tests for relevant differences as well as solutions for some specific settings often arising in practice. Drawing from real-life medical research, the author uses numerous examples throughout to illustrate the methods.

Testing Statistical Hypothesis

Author: CTI Reviews
Publisher: Cram101 Textbook Reviews
ISBN: 1467247642
Size: 70.66 MB
Format: PDF, ePub
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Facts101 is your complete guide to Testing Statistical Hypothesis. In this book, you will learn topics such as as those in your book plus much more. With key features such as key terms, people and places, Facts101 gives you all the information you need to prepare for your next exam. Our practice tests are specific to the textbook and we have designed tools to make the most of your limited study time.

Testing Statistical Hypotheses

Author: Erich L. Lehmann
Publisher: Springer Science & Business Media
ISBN: 038727605X
Size: 31.87 MB
Format: PDF, Mobi
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The third edition of Testing Statistical Hypotheses updates and expands upon the classic graduate text, emphasizing optimality theory for hypothesis testing and confidence sets. The principal additions include a rigorous treatment of large sample optimality, together with the requisite tools. In addition, an introduction to the theory of resampling methods such as the bootstrap is developed. The sections on multiple testing and goodness of fit testing are expanded. The text is suitable for Ph.D. students in statistics and includes over 300 new problems out of a total of more than 760.

Statistik F R Dummies

Author: Deborah J. Rumsey
Publisher: John Wiley & Sons
ISBN: 3527692762
Size: 37.67 MB
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Statistik ist ganz sicher kein beliebtes, aber ein notwendiges und auch nï¿1⁄2tzliches Thema. Deborah Rumsey erklï¿1⁄2rt Ihnen in diesem Buch die notwendigen Grundbegriffe, erlï¿1⁄2utert die wichtigsten statistischen Konzepte und schafft einen Bezug zwischen Theorie und Praxis. Dabei kommt Sie fast ohne Formeln aus. Sie lernen die verschiedenen grafischen Darstellungsmï¿1⁄2glichkeiten von statistischem Material kennen und erfahren, wie Sie Ihre Ergebnisse richtig auswerten. Egal ob Mittelwert, Bias, Standardabweichung oder Konfidenzintervall, schon bald kann Ihnen keiner mehr etwas vormachen.

Encyclopedia Of Biopharmaceutical Statistics Four Volume Set

Author: Shein-Chung Chow
Publisher: CRC Press
ISBN: 135111025X
Size: 80.98 MB
Format: PDF, ePub
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Since the publication of the first edition in 2000, there has been an explosive growth of literature in biopharmaceutical research and development of new medicines. This encyclopedia (1) provides a comprehensive and unified presentation of designs and analyses used at different stages of the drug development process, (2) gives a well-balanced summary of current regulatory requirements, and (3) describes recently developed statistical methods in the pharmaceutical sciences. Features of the Fourth Edition: 1. 78 new and revised entries have been added for a total of 308 chapters and a third volume has been added to encompass the increased number of chapters. 2. Revised and updated entries reflect changes and recent developments in regulatory requirements for the drug review/approval process and statistical designs and methodologies. 3. Additional topics include multiple-stage adaptive trial design in clinical research, translational medicine, design and analysis of biosimilar drug development, big data analytics, and real world evidence for clinical research and development. 4. A table of contents organized by stages of biopharmaceutical development provides easy access to relevant topics. About the Editor: Shein-Chung Chow, Ph.D. is currently an Associate Director, Office of Biostatistics, U.S. Food and Drug Administration (FDA). Dr. Chow is an Adjunct Professor at Duke University School of Medicine, as well as Adjunct Professor at Duke-NUS, Singapore and North Carolina State University. Dr. Chow is the Editor-in-Chief of the Journal of Biopharmaceutical Statistics and the Chapman & Hall/CRC Biostatistics Book Series and the author of 28 books and over 300 methodology papers. He was elected Fellow of the American Statistical Association in 1995.

Biostatistics And Microbiology A Survival Manual

Author: Daryl S. Paulson
Publisher: Springer Science & Business Media
ISBN: 9780387772820
Size: 50.66 MB
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This "nuts and bolts" book provides a condensation of biostatistical methods that applied microbiology researchers need to perform data analyses. Based on the author’s more than two decades of applied research and teaching experience, it is presented in a straight-forward manner, applicable by practicing microbiologists with minimal backgrounds in mathematics. All methods rely only on the use of a basic hand-held calculator. The overriding goal of this book is to ground one’s microbiological expertise and experience in one’s research pursuits, using biostatistics not as a black box, but as a tool.

Equivalence And Noninferiority Tests For Quality Manufacturing And Test Engineers

Author: Scott Pardo
Publisher: CRC Press
ISBN: 1466586885
Size: 47.27 MB
Format: PDF, ePub, Mobi
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In engineering and quality control, various situations, including process validation and design verification, require equivalence and noninferiority tests. Equivalence and Noninferiority Tests for Quality, Manufacturing and Test Engineers presents methods for using validation and verification test data to demonstrate equivalence and noninferiority in engineering and applied science. The book covers numerous tests drawn from the author’s more than 30 years of work in a range of industrial settings. It provides computational formulas for the tests, methods to determine or justify sample sizes, and formulas to calculate power and operating characteristic curves. The methods are accessible using standard statistical software and do not require complicated programming. The book also includes computer code and screen shots for SAS, R, and JMP. This book provides you with a guide to performing validation and verification tests that demonstrate the adequacy of your process, system, or product. It will help you choose the best test for your application.

Intraoperative Neurophysiological Monitoring For Deep Brain Stimulation

Author: Erwin B Montgomery, Jr
Publisher: Oxford University Press
ISBN: 0199351023
Size: 45.31 MB
Format: PDF
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A thorough understanding of electricity, electronics, biophysics, neurophysiology, and neuroanatomy is important to render more tractable, and otherwise complex, electrophysiologically-based targeting in the brain during operative manipulations. Most importantly, electrophysiological monitoring requires controlling the movement of electrons in electronic circuits in order to prevent irreversible damage. This new textbook presents a fundamental discussion of electrons, the forces moving these electrons, and the electrical circuits controlling these forces. The forces that allow recording and analysis also permeate the environment producing interference, such as noise and artifacts. Intraoperative Neurophysiological Monitoring for Deep Brain Stimulation discusses how to avoid or suppress noise and artifacts for the most successful surgical outcome.

20 Things To Know About Deep Brain Stimulation

Author: Erwin B. Montgomery, Jr.
Publisher: Oxford University Press
ISBN: 0199338841
Size: 79.93 MB
Format: PDF, ePub
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Twenty Things to Know About Deep Brain Stimulation is an extensive and in-depth critical analysis of the field of Deep Brain Stimulation (DBS) from what many may consider a revolutionary perspective. This book demonstrates the unique nature and incredible promise of DBS and shows how it is unparalleled as a therapeutic intervention. Dr. Montgomery provides an epistemic analysis of the presuppositions, assumptions and fallacies underlying current clinical understanding of DBS as well as the physiology and pathophysiology affected by DBS. Reviews of the safety and efficacy for a number of conditions, patient selections and issues in the post-operative management are also included. Given the revolutionary potential and the complexity of DBS in an ever changing healthcare delivery context, the ethics of DBS are discussed in detail.