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The Cytokines Of The Immune System

Author: Zlatko Dembic
Publisher: Academic Press
ISBN: 0124200109
Size: 17.24 MB
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The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. Supplies new ideas for basic and clinical research Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials Offers a textbook-style view on the immune system with the immunologic role of each cytokine

Cytokines And Cytokine Receptors

Author: Constantin A. Bona
Publisher: CRC Press
ISBN: 0203305132
Size: 24.61 MB
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The field of cytokine research is expanding at a rapid pace Contributions from the major leading groups in the world on the structure and biological properties of cytokine and cytokine receptors, as well as integrated reviews on cytokines in various physiological and pathological conditions were presented in three issues of International Reviews of Immunology This collection of articles provided a unique source of information However, important discoveries are emerging very rapidly and some of the reviews written in 1997 are already outdated In this book, the editors assemble reviews that have been updated by their authors to include all the recent publications and unpublished data from the authors' laboratories This volume should serve as an excellent reference source for all those concerned by the multiple faces of cytokines in basic research and in the clinic

Clinical Applications Of Cytokines

Author: Joost J. Oppenheim
Publisher: Oxford University Press, USA
ISBN: 9780195071290
Size: 51.28 MB
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The driving force for research on cytokines has always been their clinical promise. Their biological properties suggested a key role in hematopoiesis, immunity, tumor genesis, hemostasis, vascularization, repair of connective tissues and integration of the immune system with the neuroendocrine system. Animal studies have shown that cytokines could be used as effective biotherapeutics with easily manageable and reversible toxicities. Clinical trials have confirmed these findings, culminating in the licensing of a number of the cytokines such as interferon alpha, interferon gamma, interleukin 2, erythropoietin, granulocyte colony stimulating factor, and granulocyte-macrophage colony stimulating factor. Many other cytokines are in clinical trials. This is the first comprehensive volume on the cytokines written primarily from a medical perspective. After presenting background information about the structure, production, assays and systemic effects of cytokines and their receptors, it is organized around diseases and organ systems. Infectious diseases, autoimmunity, immunodeficiency states, defective hematopoiesis, allergies, injury repair, cancer, vascular and skin diseases, and neurological disorders are all covered. This work reviews the role that cytokines play in the pathogenesis, diagnosis and therapy of each disease. The authors assess both the current state of the art and the potential for future applications.

Cytokines

Author: Robert E. Faith
Publisher: CRC Press
ISBN: 1420003801
Size: 41.52 MB
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Cytokine involvement in the immune system's response to stress is now very well documented. Cytokine activity has been implicated in a variety of mental and physical diseases, and has been shown to have a significant role in fueling the vicious circle of depression and illness. The first edition of Cytokines: Stress and Immunity pointed out that the immune system does not stand alone, but is profoundly affected by other organ systems, especially the central nervous and the neuroendocrine systems, with cytokines being the common tool of communication. This edition continues on the trailblazing path of the original to once again present current research that informs our evolving understanding of how cytokines function and the clinical implications of cytokine activity. Completely rewritten by the top authorities in their fields, this volume includes 16 entirely new chapters, which document dramatic new developments. It provides a comprehensive overview of the role of cytokines in the neuroendocrine and immune systems, while also addressing the interactions between these systems. It examines cytokine activity and clinical implications from a number of perspectives, including those of immunology, pharmacology, oncology, endocrinology, and psychiatry. Researchers involved with the most specific aspects of cell signaling as well clinicians dealing with the effects of immunosuppression-related diseases will find a wealth of interesting and instantly applicable information. This new edition begins with an extended dedication and tribute to the late Robert A. Good, the father of modern immunology. It documents the life and groundbreaking achievements of Dr. Good who served as an editor for both the former and current editions of this work.

Inflammatory Bowel Diseases

Author: Bruce R. Bistrian
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805568851
Size: 17.19 MB
Format: PDF, Kindle
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Annotation. "The contributions in this volume focus on nutritional therapy, which is important for both the repletion of associated protein-energy malnutrition and for modulation of the inflammatory response. Highlights include the growing role of enteral nutrition as primary therapy in pediatric practice and investigations into the ideal diet composition, including type of formula (polymeric, protein hydrolysate or amino acid). Furthermore, the pro- and anti-inflammatory effects of [omega]-6 and [omega]-3 fatty acids, respectively, and their impact on clinical response receive special attention."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved.

Infectious Diseases Of The Female Genital Tract

Author: Richard L. Sweet
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781778152
Size: 73.34 MB
Format: PDF, Docs
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Organised by organism and then by disease this comprehensive reference provides contemporary diagnostic and therapeutic information on bacterial and viral infections of the female genital tract.

Biologic Response Modifiers In Infectious Diseases An Issue Of Infectious Disease Clinics E Book

Author: Nancy M. Khardori
Publisher: Elsevier Health Sciences
ISBN: 1455712078
Size: 42.53 MB
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Biologic response modifiers (BRMs) are substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating infections and other diseases. This issue reviews the use of BRMs to treat infectious diseases as well as the infectious complications of BRMs used to treat non-infectious diseases. Articles on vaccines, antibodies, interferon, and other substances are included.

Cytokine Gene Polymorphisms In Multifactorial Conditions

Author: Koen Vandenbroeck
Publisher: CRC Press
ISBN: 1420005324
Size: 70.46 MB
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The literature on cytokine genetics is vast, so vast that it is now practically beyond the time or logistical constraints of most scientists to successfully keep pace with it. A compilation of the latest research, Cytokine Gene Polymorphisms in Multifactorial Conditions brings together, reviews, and structures up-to-date information on polymorphisms in cytokine genes. It discusses haplotype structures and linkage disequilibrium patterns in cytokine gene loci; functional biological effects of polymorphisms; and genetic associations with disease. The book documents polymorphisms in the most important cytokine genes, or gene clusters, and their biological and genetic effects in a multitude of distinct multifactorial conditions. Unique to this book are the "disease-centered" chapters examining the role of cytokine gene polymorphisms in a multitude of multifactorial conditions. The conditions include autoimmune or chronic inflammatory diseases, cardiovascular disease, infectious diseases, and longevity. "This section is a real tour de force" (Grant Gallagher and Michael F. Seldin, March 2006). Broadening the understanding of the effect of genetic variations on human immune responses, the organization, scope, and content of this book make it a valuable and easily accessible resource. The book integrates genetic, immunological, and clinical information and will serve as a reference for novice and expert geneticists, immunologists, cell biologists and clinicians. It is a must for everyone involved in, or planning, cytokine genetics or immunogenetics studies.

Cellular And Molecular Immunology E Book

Author: Abul K. Abbas
Publisher: Elsevier Health Sciences
ISBN: 1437735738
Size: 79.10 MB
Format: PDF
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Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. This reference is the up-to-date and readable textbook you need to master the complex subject of immunology. Recognize the clinical relevance of the immunology through discussions of the implications of immunologic science for the management of human disease. Grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. Stay abreast of the latest advances in immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more. Visualize immunologic processes more effectively through a completely revised art program with redrawn figures, a brighter color palette, and more 3-dimensional art. Find information more quickly and easily through a reorganized chapter structure and a more logical flow of material.

Liver A Complete Book On Hepato Pancreato Biliary Diseases E Book

Author: Mamun-Al Mahtab
Publisher: Elsevier Health Sciences
ISBN: 8131231577
Size: 47.37 MB
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The spectrum and etiology of liver diseases vary widely between East and West and hence the focus and experience of hepatologists also remain varied at two corners of the globe. Hepatology being perhaps one of the most flourishing and evolving discipline of medical sciences, a book with recent information written by experts from all over the world was much needed. The present book fulfills this need. The book will serve as a useful reference manual to consultants, postgraduate students, and residents of Hepatology, Gastroenterology, Internal Medicine, Pathology, Virology, and Preventive Medicine as well as undergraduate clinical medical students. Liver is a comprehensive book that discusses all aspects of diseases ranging from epidemiology to prognosis. This book is unique in its conception and presentation, as not only it provides new information but also offers a balanced and rational approach to diseases of liver, pancreas, and biliary system. One of the characteristic features of the book is inclusion of diseases of pancreas and separate chapters on important topics like cytokines and chemokines and apoptosis in liver diseases, as a sound background in these is essential for becoming a good specialist. It contains a chapter on evidence-based clinical practice in hepatology, which is the basis of modern clinical practice. It also includes a chapter on preventive aspects of hepato-biliary diseases keeping in mind that prevention of diseases is always preferred to cure. One of the unique features of this book is, it has contributors from all over the world.