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The Dynamic Bacterial Genome

Author: Peter Mullany
Publisher: Cambridge University Press
ISBN: 9780521821575
Size: 32.48 MB
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This book is concerned with the mechanisms underlying recombination in bacterial DNA.

Bacterial Protein Toxins

Author: Alistair J. Lax
Publisher: Cambridge University Press
ISBN: 9781139443593
Size: 64.28 MB
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Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context.

Antimicrobial Peptides

Author: Guangshun Wang
Publisher: CABI
ISBN: 1786390396
Size: 52.65 MB
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Antimicrobial peptides (AMPs) have attracted extensive research attention worldwide. Harnessing and creating AMPs synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. This new edition lays the foundations for studying AMPs, including a discovery timeline, terminology, nomenclature and classifications. It covers current advances in AMP research and examines state-of-the-art technologies such as bioinformatics, combinatorial libraries, high-throughput screening, database-guided identification, genomics and proteomics-based prediction, and structure-based design of AMPs. Thoroughly updated and revised, this second edition contains new content covering: defensins; cathelicidins; anti-MRSA, antifungal, antiviral, anticancer and antibiofilm strategies; combined treatments; adjuvants in vaccines; advances in AMP technologies that cover surface coating to prevent biofilm formation; nanofiber encapsulation technologies for delivery and sustained release; and understanding innate immunity and the basis for immune boosting to overcome obstacles in developing AMPs into therapeutic agents. Written and reviewed by a group of established investigators in the field, Antimicrobial Peptides is a valuable resource for postgraduate students, researchers, educators, and medical and industrial personnel.

Molecular Medical Microbiology Three Volume Set

Author: Yi-Wei Tang
Publisher: Elsevier
ISBN: 0080536883
Size: 56.28 MB
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The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative 3-volume work is an invaluable reference source of medical bacteriology. Comprising over 100 chapters, organised into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. * The first comprehensive and accessible reference on Molecular Medical Microbiology * Two color presentation throughout * Full colour plate section * Fully integrated and meticulously organised * In depth discussion of individual pathogenic bacteria in a system-oriented approach * Includes a clinical overview for each major bacterial group * Presents the latest information on vaccine development, molecular technology and diagnostic technology * Extensive indexing and cross-referencing throughout * Over 100 chapters covering all major groups of bacteria * Written by an international panel of authors expert in their respective disciplines * Over 2300 pages in three volumes

Plasmid Biology

Author: Gregory Phillips
Publisher: Amer Society for Microbiology
Size: 43.82 MB
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This book opens with an essay on the historical perspective of the study of plasmids, reviewing important events and discoveries that have propelled the field forward. The remaining chapters are divided into six sections, detailing basic biological processes such as replication and inheritance functions, specific plasmid systems, plasmid evolution, and use of plasmids as genetic tools. Chapters include use of genomic approaches for the study of plasmid biology, and a review of plasmids from bacteria, archaea, and eukaryotes is presented. In-depth treatment is given to diversity of plasmid systems in the natural environment, and the development of plasmid use in the laboratory is also covered.

Salmonella Infections

Author: Duncan Maskell
Publisher: Cambridge University Press
ISBN: 1107320623
Size: 46.79 MB
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Salmonella enterica encompasses a diverse range of bacteria that cause a spectrum of diseases in many hosts. Advancements in prevention and treatment of S. enterica infections have at times been hampered by compartmentalization of research efforts and lack of multidisciplinary approaches. This book attempts to cover a diverse range of topics related to the biology of S. enterica infections, including epidemiological and clinical aspects, molecular pathogenesis, immunity to disease and vaccines. S. enterica infections are important zoonoses and therefore material on infections of animals and public health issues have also been considered. Each chapter can be read independently, but the full contents of the book will provide the reader with up-to-date knowledge on all the key aspects of salmonellosis in humans and animals. It will therefore be of interest to graduate students and researchers, as well as to clinicians, whose research focuses on this important pathogen.


Author: Peter L. Graumann
Publisher: Caister Academic Press
ISBN: 1910190586
Size: 42.90 MB
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The third edition of this authoritative reference work is indispensable to Bacillus scientists and invaluable for anyone involved in bacterial cell biology. Revised, updated and expanded with two new chapters on motility and nucleotide regulation, the new edition provides up-to-date reviews on current Bacillus research. Subjects covered include chromosome replication, DNA repair, chromosome segregation, cell division, transcription and translation, RNA-mediated regulation, general and regulatory proteolysis, the MreB cytoskeleton, membrane proteins, the cell wall, sporulation, biofilms, multicellularity and social behaviour, competence and transformation, motility and nucleotide regulation. An essential book for anyone involved in Bacillus and an invaluable reference work for those working in fields as diverse as medicine, biotechnology, agriculture, food and industry. A recommended acquisition for all microbiology laboratories.

Cellular Microbiology

Author: Pascale Cossart
Publisher: Amer Society for Microbiology
Size: 36.55 MB
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A comprehensive examination of this burgeoning area of important research. - Covers bacterial human pathogen genomes, structure and dynamics of the host cell membrane, study of prokaryotic biology using genome-wide approaches, cell biology of virus infection, and use of simple nonvertebrate hosts to model mammalian pathogenesis. - Acquaints scientists and graduate-level students with a valuable source of reference in an emerging field. - Integrates the two important fields of cell biology and microbiology.


Author: Holger Brüggemann
Publisher: Horizon Scientific Press
ISBN: 1904455387
Size: 63.34 MB
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"In this book internationally recognized Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. Essential reading for every clostridia researcher, from the PhD student to the experienced scientist, as it provides a timely review of current research." --Book Jacket.

Microbial Population Genetics

Author: Jianping Xu
Publisher: Horizon Scientific Press
ISBN: 190445559X
Size: 75.27 MB
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Microbial population genetics is a rapidly advancing field of investigation with relevance to many areas of science. The subject encompasses theoretical issues, such as the origins and evolution of species, sex, and recombination. Population genetics lays the foundations for tracking the origin and evolution of antibiotic resistance and deadly infectious pathogens and is also an essential tool in the utilization of beneficial microbes. This invaluable book, written by leading researchers in the field, details the current major advances in microbial population genetics and genomics. Distinguished international scientists introduce fundamental concepts, describe genetic tools, and comprehensively review recent data from SNP surveys, whole-genome DNA sequences, and microarray hybridizations. The chapters cover broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa, and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics covered include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens, and metagenomics. Microbial Population Genetics is an essential volume for everyone interested in population genetics, and it is highly recommended reading for all microbiologists.