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The Hippocampus From Cells To Systems

Author: Deborah E. Hannula
Publisher: Springer
ISBN: 3319504061
Size: 64.78 MB
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The hippocampus has long been considered a critical substrate in the neurobiology, neuropsychology, and cognitive neuroscience of memory. Over the past few decades, a number of ground-breaking theoretical and methodological advances have radically enhanced our understanding of the structure and function of the hippocampus and revolutionized the neuroscientific study of memory. Cutting across disciplines and approaches, these advances offer novel insights into the molecular and cellular structure and physiology of the hippocampus, the role of hippocampus in the formation, (re)consolidation, enhancement, and retrieval of memory across time and development, and permit investigators to address questions about how the hippocampus interacts, functionally and anatomically, with other neural systems in service of memory. In addition, recent investigations also suggest that the mechanistic properties and functional processing features of the hippocampus permit broader contributions to cognition, beyond memory, to the domains of attention, decision-making, language, social cognition, and a variety of other capacities that are critical for flexible cognition and behavior. These advances have profound implications for the neurobiology and cognitive neuroscience of hippocampus dependent cognition and for the numerous psychiatric and neurological diseases and disorders for which hippocampal pathology is a hallmark such as Alzheimer’s disease and schizophrenia. The goal of this book is to bring together in a single source an integrated review of these advances providing state of the art treatment on the structure and function of the hippocampus. Contributors will examine the hippocampus from a variety of levels (from cells to systems) using a wide range of methods (from neurobiological approaches in non-human animals to neuroimaging and neuropsychological work in humans).

The Human Hippocampus

Author: Henri M. Duvernoy
Publisher: Springer Science & Business Media
ISBN: 3662036282
Size: 16.19 MB
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A precise description of the anatomy and structure of the human hippocampus together with a survey of the current concepts about its functions and their clinical implications. Chapters on vascularization and three-dimensional MRI round off the study, making this of interest to everyone working in the field of neuroscience, particularly neurologists, neuroradiologists and neurosurgeons concerned with epilepsy.

Brain Organization And Memory

Author: James L. McGaugh
Publisher: Oxford University Press on Demand
ISBN: 0195077121
Size: 67.49 MB
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This edited volume summarizes recent findings of leading researchers investigating the brain systems that underlie memory. The book reviews recent progress in understanding forms of memory in animals and humans and the interaction of cortical and subcortical systems in the regulation of memory. Special emphasis is given to the development of neural network models that attempt to link cells to systems in the representation of memory. The book will be an invaluable source for cognitive psychologists, neuroscientists, and students interested in this active and exciting area of research.

Hippocampal Place Fields

Author: Sheri J.Y. Mizumori
Publisher: Oxford University Press
ISBN: 0198043457
Size: 12.46 MB
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Data from neuropsychological and animal research suggest that the hippocampus plays a pivotal role in two relatively different areas: active navigation, as well as episodic learning and memory. Recent studies have attempted to bridge these disparate accounts of hippocampal function by emphasizing the role that hippocampal place cells may play in processing the spatial contextual information that defines situations in which learned behaviors occur. A number of established laboratories are currently offering complementary interpretations of place fields, and this book will present the first common platform for them. Bringing together research from behavioral, genetic, physiological, computational, and neural-systems perspectives will provide a thorough understanding of the extent to which studying place-field properties has informed our understanding of the neural mechanisms of hippocampus-dependent memory. Hippocampal Place Fields: Relevance to Learning and Memory will serve as a valuable reference for everyone interested in hippocampal function.

Beyond The Cognitive Map

Author: A. David Redish
Publisher: MIT Press
ISBN: 9780262181945
Size: 34.72 MB
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There are currently two major theories about the role of the hippocampus, a distinctive structure in the back of the temporal lobe. One says that it stores a cognitive map, the other that it is a key locus for the temporary storage of episodic memories. A. David Redish takes the approach that understanding the role of the hippocampus in space will make it possible to address its role in less easily quantifiable areas such as memory. Basing his investigation on the study of rodent navigation -- one of the primary domains for understanding information processing in the brain -- he places the hippocampus in its anatomical context as part of a greater functional system. Redish draws on the extensive experimental and theoretical work of the last 100 years to paint a coherent picture of rodent navigation. His presentation encompasses multiple levels of analysis, from single-unit recording results to behavioral tasks to computational modeling. From this foundation, he proposes a novel understanding of the role of the hippocampus in rodents that can shed light on the role of the hippocampus in primates, explaining data from primate studies and human neurology. The book will be of interest not only to neuroscientists and psychologists, but also to researchers in computer science, robotics, artificial intelligence, and artificial life.

Space Time And Memory In The Hippocampal Formation

Author: Dori Derdikman
Publisher: Springer
ISBN: 3709112923
Size: 37.41 MB
Format: PDF
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The discovery of new cell types, such as grid and time cells, in the hippocampus has been accompanied by major anatomical and theoretical insights in the recent years. This book provides comprehensive, up-to-date information about the hippocampal formation and especially the neural basis of episodic memory, spatial location (the formation of the cognitive map) and temporal representation. The first part of the book describes the information flow from pre-hippocampal areas into the hippocampus, the second part discusses the different types of hippocampal processing and finally, the third part depicts the influence that the hippocampal processing has on other brain structures that are perhaps more closely tied to explicit cognitive or behavioral output. This book is intended for neuroscientists, especially for those who are involved in research on the hippocampus, as well as for behavioral scientists and neurologists.

The Hippocampus Book

Author: Per Andersen
Publisher: Oxford University Press
ISBN: 9780195100273
Size: 39.14 MB
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The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book brings together contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain.

Functions Of The Septo Hippocampal System

Author: CIBA Foundation Symposium
Publisher: John Wiley & Sons
ISBN: 0470718080
Size: 42.20 MB
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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

A New Foundation For Representation In Cognitive And Brain Science

Author: Jaime Gómez Ramirez
Publisher: Springer Science & Business Media
ISBN: 9400777388
Size: 28.53 MB
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The purpose of the book is to advance in the understanding of brain function by defining a general framework for representation based on category theory. The idea is to bring this mathematical formalism into the domain of neural representation of physical spaces, setting the basis for a theory of mental representation, able to relate empirical findings, uniting them into a sound theoretical corpus. The innovative approach presented in the book provides a horizon of interdisciplinary collaboration that aims to set up a common agenda that synthesizes mathematical formalization and empirical procedures in a systemic way. Category theory has been successfully applied to qualitative analysis, mainly in theoretical computer science to deal with programming language semantics. Nevertheless, the potential of category theoretic tools for quantitative analysis of networks has not been tackled so far. Statistical methods to investigate graph structure typically rely on network parameters. Category theory can be seen as an abstraction of graph theory. Thus, new categorical properties can be added into network analysis and graph theoretic constructs can be accordingly extended in more fundamental basis. By generalizing networks using category theory we can address questions and elaborate answers in a more fundamental way without waiving graph theoretic tools. The vital issue is to establish a new framework for quantitative analysis of networks using the theory of categories, in which computational neuroscientists and network theorists may tackle in more efficient ways the dynamics of brain cognitive networks. The intended audience of the book is researchers who wish to explore the validity of mathematical principles in the understanding of cognitive systems. All the actors in cognitive science: philosophers, engineers, neurobiologists, cognitive psychologists, computer scientists etc. are akin to discover along its pages new unforeseen connections through the development of concepts and formal theories described in the book. Practitioners of both pure and applied mathematics e.g., network theorists, will be delighted with the mapping of abstract mathematical concepts in the terra incognita of cognition.