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Biochemistry Of Human Cancer

Author: Oscar Bodansky
Publisher: Elsevier
ISBN: 0323143636
Size: 69.58 MB
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Biochemistry of Human Cancer focuses on advances in the application of biochemistry to the study of human cancers, such as neoplastic immunoglobulinopathies, cancer of the bladder, tumors of the neural crest, leukemias and lymphomas, and neoplasms of the bone. It also examines certain features of human cancer ranging from general metabolic characteristics to enzymic aspects and immunochemical considerations. Organized into 18 chapters, this book begins with an overview of the general metabolic features of cancer, with emphasis on the metabolism of lipids, proteins, and carbohydrates. It then discusses the important biochemical aspects of pulmonary and prostatic neoplasms, including the serum acid and alkaline phosphatase activities of prostatic carcinoma. The remaining chapters look at the role of enzymes and immunoglobulins in cancer, the tryptophan metabolism in cancer of the bladder and the carcinoid syndrome, the link between amino acid metabolism and tumors of the neural crest, and the neoplasms of the digestive tract and the accessory organs (pancreas and liver). The book explains the metabolism of purines and pyrimidines in cancer, hypercalcemia in neoplastic disease without evidence of bone metastases, and neoplasms of other organs, such as the pituitary gland, thyroid, testis, and adrenal cortex. Brief case reports from the literature are included to illustrate correlations between biochemical and clinical findings. Scientists, biochemists, and clinical investigators concerned with the biochemistry of human cancer will find this book highly informative.

Biology Of Fertilization V2

Author: Charles Metz
Publisher: Elsevier
ISBN: 032314814X
Size: 39.16 MB
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Biology of Fertilization, Volume 2: Biology of the Sperm is the second in a three-volume series that brings together various lines of research about reproduction in general and fertilization in particular. It is devoted to spermatogenesis, sperm physiology, and the initial interactions of sperm with egg components. The book is organized into three parts. Part I on spermatogenesis and sperm physiology includes studies on the evolution of the sperm cell; regulatory mechanisms, sperm antigen differentiation, and maturation of sperm in the reproductive tracts in mammals; physicochemical mechanisms of the acrosome filament extrusion process; and enzymes associated with sperm cell function. Part II deals with chemotaxis in microorganisms: bacteria and slime molds. Part III on gamete recognition and binding includes studies on identifying, isolating, and characterizing specific sperm and egg surface components involved in sperm-egg interaction; fertilization in the alga Fucus; fertilization in insects; and the role of lysins in fertilization.

Advances In Physiology Biochemistry And Function

Author: A.D. Johnson
Publisher: Elsevier
ISBN: 0323143741
Size: 64.90 MB
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The Testis: Advances in Physiology, Biochemistry, and Function, Volume IV, provides an overview of the state of knowledge in the physiology, biochemistry, and function of the testis. This volume updates those areas of greatest research activity and introduces in a more complete manner those topics which have developed as subject areas in themselves. It includes a chapter on testicular steroidogenesis, which updates and expands the chapter appearing in Volume II. In addition, chapters on the role of FSH in the testis, the specialized (largely endocrine) functions of the Sertoli cells, and the entire account of the tubular hormone inhibin have all been extensions of material in the original chapter on testicular endocrinology. Similarly, separate chapters on blood flow in the testis, fluid secretion, and the blood-testis barrier all report data on subjects largely unsuspected when Volumes I-III were published. Neither the first three volumes nor is the present one intended primarily for the nonprofessional biologist or the popular reader. The coverage should be most useful and informative to professional biologists. It is anticipated that this volume will also be of interest to advanced students of animal biology as an authoritative, comprehensive, and convenient review of significant recent information concerning the testis.

Cell And Molecular Biology Of The Testis

Author: Des Jardins
Publisher: New York : Oxford University Press
ISBN: 9780195062694
Size: 21.18 MB
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This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.

Recent Advances In Steroid Biochemistry

Author: J. R. Pasqualini
Publisher: Elsevier
ISBN: 1483140148
Size: 57.61 MB
Format: PDF
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Recent Advances in Steroid Biochemistry contains the proceedings of the Second International Symposium of the Journal of Steroid Biochemistry. Separating 38 papers as chapters, this book discusses the partial purification of steroid-receptor complexes; enzymatic techniques in steroid assay; mass fragmentography of steroid hormones; biological consequences of 18-hydroxylation; and steroidogenesis in adrenal cells. This text also explores the regulation of steroidogenesis in testis; androgen binding proteins in different testis compartments; nuclear acceptor sites for glucocorticoid receptors; estrogen receptors in the pancreas; and molecular mechanisms of steroid hormone action.

Knobil And Neill S Physiology Of Reproduction

Author: Tony M. Plant
Publisher: Academic Press
ISBN: 012397769X
Size: 80.60 MB
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The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. The new edition synthesizes all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context. The Fourth Edition has been extensively revised, reflecting new fundamental advancements in this rapidly advancing field. Provides a common language for researchers across the fields of physiology, endocrinology, and biology to discuss their understanding of reproduction. Saves academic researchers time in quickly accessing the very latest details on reproductive physiology, as opposed to searching through thousands of journal articles.

Essentials Of Medical Biochemistry

Author: Chung-Eun Ha
Publisher: Academic Press
ISBN: 9780080916880
Size: 31.41 MB
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View: 2004
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Expert biochemist N.V. Bhagavan’s new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions, Bhagavan provides the reader with the most condensed yet detailed biochemistry overview available. More than a quick survey, this comprehensive text includes USMLE sample exams from Bhagavan himself, a previous coauthor. * Clinical focus emphasizing relevant physiologic and pathophysiologic biochemical concepts * Interactive multiple-choice questions to prep for USMLE exams * Clinical case studies for understanding basic science, diagnosis, and treatment of human diseases * Instructional overview figures, flowcharts, and tables to enhance understanding