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The Vaccine Race

Author: Meredith Wadman
Publisher: Penguin
ISBN: 0698177789
Size: 70.30 MB
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“Riveting . . . [The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks.”—Nature “This is a story about the war against disease—a war without end—and the development of enormously important vaccines, but in telling that story, in showing how science works, Meredith Wadman reveals much more. I loved this book.” —John M. Barry, New York Times bestselling author of The Great Influenza The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

The Vaccine Race

Author: Meredith Wadman
Publisher: Penguin
ISBN: 0525427538
Size: 67.82 MB
Format: PDF, ePub
View: 3328
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"The rubella vaccine and others made with ... fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles, and adenovirus. Meredith Wadman's [book] covers not only the science of this [advancement], but also the political roadblocks that nearly stopped the scientists"--Provided by publisher.

The Vaccine Race

Author: Meredith Wadman
Publisher: Random House
ISBN: 1473509378
Size: 80.27 MB
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View: 3767
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**SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2018 ** ** A GUARDIAN SCIENCE BOOK OF THE YEAR 2017 ** ‘Riveting ... invites comparison to Rebecca Skloot's The Immortal Life of Henrietta Lacks’ Nature The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant. There was no vaccine and little understanding of how the disease devastated foetuses. In June 1962, a young biologist in Philadelphia produced the first safe, clean cells that made possible the mass-production of vaccines against many common childhood diseases. Two years later, in the midst of a German measles epidemic, his colleague developed the vaccine that would one day effectively wipe out rubella for good. This vaccine - and others made with those cells - have since protected hundreds of millions of people worldwide, the vast majority of them preschool children. Meredith Wadman’s account of this great leap forward in medicine is a fascinating and revelatory read.

Genetics And Evolution Of Infectious Diseases

Author: Michel Tibayrenc
Publisher: Elsevier
ISBN: 0128001534
Size: 76.13 MB
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Genetics and Evolution of Infectious Diseases, Second Edition, discusses the constantly evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world. Students in public health, biomedical professionals, clinicians, public health practitioners, and decisions-makers will find valuable information in this book that is relevant to the control and prevention of neglected and emerging worldwide diseases that are a major cause of global morbidity, disability, and mortality. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases during the last century, in recent decades the world has witnessed a worldwide human immunodeficiency virus (HIV) pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. The economic, social, and political burden of infectious diseases is most evident in developing countries which must confront the dual burden of death and disability due to infectious and chronic illnesses. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field of infectious disease

The Vaccine Race

Author: Meredith Wadman
Publisher: Black Swan
ISBN: 9781784160135
Size: 39.77 MB
Format: PDF, ePub, Docs
View: 3595
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**LONGLISTED FOR THE WELLCOME BOOK PRIZE 2018 ** ** A GUARDIAN SCIENCE BOOK OF THE YEAR 2017 ** 'Riveting ... invites comparison to Rebecca Skloot's The Immortal Life of Henrietta Lacks' Nature The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases. Until the late 1960s, tens of thousands of children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant. There was no vaccine and little understanding of how the disease devastated foetuses. In June 1962, a young biologist in Philadelphia produced the first safe, clean cells that made possible the mass-production of vaccines against many common childhood diseases. Two years later, in the midst of a German measles epidemic, his colleague developed the vaccine that would one day effectively wipe out rubella for good. This vaccine - and others made with those cells - have since protected hundreds of millions of people worldwide, the vast majority of them preschool children. Meredith Wadman's account of this great leap forward in medicine is a fascinating and revelatory read.

Essential Microbiology

Author: Stuart Hogg
Publisher: John Wiley & Sons
ISBN: 1118688147
Size: 42.51 MB
Format: PDF, Docs
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Essential Microbiology is a comprehensive introductory text aimed at students taking a first course in the subject. Covering all aspects of microbiology, it describes the structure and function of microbes before considering their place in the the living world. The second half of the book focuses on applied aspects such as genetic engineering, industrial microbiology and the control of microorganisms. Adopting a modern approach and with extensive use of clear comprehensive diagrams, Essential Microbiology explains key topics through the use of definition boxes and end of chapter questions. This book is invaluable for undergraduate students in the biological, food and health sciences taking a first course in Microbiology. comprehensive introduction covering all aspects of this exciting subject. includes numerous examples and applications from a wide range of fields. definition boxes, key points and self-test questions enhance student understanding.

Vaccine

Author: Arthur Allen
Publisher: W. W. Norton & Company
ISBN: 9780393059113
Size: 26.16 MB
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A definitive history of vaccination ranges from Edward Jenner's 1796 creation of the world's first smallpox inoculation to the present day, looking at both the benefits of vaccination as well as the current controversy over their potential neurological side effects and the pharmaceutical companies' emphasis on treatment rather than prevention.

The Politics Of Fear

Author: Michiel Hofman
Publisher: Oxford University Press
ISBN: 0190624493
Size: 38.51 MB
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The 2014-2015 Ebola epidemic in West Africa was an unprecedented medical and political emergency that cast an unflattering light on multiple corners of government and international response. Fear, not rational planning, appeared to drive many decisions made at population and leadership levels, which in turn brought about a response that was as uneven as it was unprecedented: entire populations were decimated or destroyed, vaccine trials were fast-tracked, health staff died, untested medications were used (or not used) in controversial ways, humanitarian workers returned home to enforced isolation, and military was employed to sometimes disturbing ends. The epidemic revealed serious fault lines at all levels of theory and practice of global public health: national governments were shown to be helpless and unprepared for calamity at this scale; the World Health Organization was roundly condemned for its ineffectiveness; the US quietly created its own African CDC a year after the epidemic began. Amid such chaos, M?decins sans Fronti?res was forced to act with unprecdented autonomy -- and amid great criticism -- in responding to the disease, taking unprecedented steps in deploying services and advocating for international aid. The Politics of Fear provides a primary documentary resource for recounting and learning from the Ebola epidemic. Comprising eleven topic-based chapters and four eyewitness vignettes from both MSF- and non-MSF-affiliated contributors (all of whom have been given access to MSF Ebola archives from Guinea, Sierra Leone, and Liberia for research), it aims to provide a politically agnostic account of the defining health event of the 21st century so far, one that will hopefully inform current opinions and future responses.

Germ Wars

Author: Melanie Armstrong
Publisher: Univ of California Press
ISBN: 0520966147
Size: 17.97 MB
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The United States government has spent billions of dollars to prepare the nation for bioterrorism despite the extremely rare occurrence of biological attacks in modern American history. Germ Wars argues that bioterrorism has emerged as a prominent fear in the modern age, arising with the production of new forms of microbial nature and the changing practices of warfare. In the last century, revolutions in biological science have made visible a vast microscopic world, and in this same era we have watched the rise of a global war on terror. Germ Wars demonstrates that these movements did not occur separately but are instead deeply entwined—new scientific knowledge of microbes makes possible new mechanisms of war. Whether to eliminate disease or create weapons, the work to harness and control germs and the history of these endeavors provide an important opportunity for investigating how biological natures shape modern life. Germ Wars aims to convince students and scholars as well as policymakers and activists that the ways in which bioterrorism has been produced have consequences for how people live in this world of unspecifiable risks.

The End Of Epidemics

Author: Dr. Jonathan D. Quick
Publisher:
ISBN: 1250117771
Size: 14.24 MB
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A leading doctor offers answers on the one of the most urgent questions of our time: How do we prevent the next global pandemic? The 2014 Ebola epidemic in Liberia terrified the world—and revealed how unprepared we are for the next outbreak of an infectious disease. Somewhere in nature, a killer virus is boiling up in the bloodstream of a bird, bat, monkey, or pig, preparing to jump to a human being. This not-yet-detected germ has the potential to wipe out millions of lives over a matter of weeks or months. That risk makes the threat posed by ISIS, a ground war, a massive climate event, or even the dropping of a nuclear bomb on a major city pale in comparison. In The End of Epidemics, Harvard Medical School faculty member and Chair of the Global Health Council Dr. Jonathan D. Quick examines the eradication of smallpox and devastating effects of influenza, AIDS, SARS, and Ebola. Analyzing local and global efforts to contain these diseases and citing firsthand accounts of failure and success, Dr. Quick proposes a new set of actions which he has coined “The Power of Seven,” to end epidemics before they can begin. These actions include: - Spend prudently to prevent disease before an epidemic strikes, rather than spending too little, too late - Ensure prompt, open, and accurate communication between nations and aid agencies, instead of secrecy and territorial disputes - Fight disease and prevent panic with innovation and good science Practical and urgent, The End of Epidemics is crucial reading for citizens, health professionals, and policy makers alike.