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Traditional Herbal Medicine Research Methods

Author: Willow J.H. Liu
Publisher: John Wiley & Sons
ISBN: 0470922664
Size: 70.34 MB
Format: PDF, Kindle
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This book introduces the methodology for collection and identification of herbal materials, extraction and isolation of compounds from herbs, in vitro bioassay, in vivo animal test, toxicology, and clinical trials of herbal research. To fully understand and make the best use of herbal medicines requires the close combination of chemistry, biochemistry, biology, pharmacology, and clinical science. Although there are many books about traditional medicines research, they mostly focus on either chemical or pharmacological study results of certain plants. This book, however, covers the systematic study and analysis of herbal medicines in general – including chemical isolation and identification, bioassay and mechanism study, pharmacological experiment, and quality control of the raw plant material and end products.

Nuclear Magnetic Resonance

Author: Jacek Wojcik
Publisher: Royal Society of Chemistry
ISBN: 1849737673
Size: 37.10 MB
Format: PDF, ePub
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With over 17,000 articles concerning NMR published per year, keeping up to date with the latest developments and applications of this technique can prove time-consuming. Now in its 42nd volume, the Specialist Periodical Report on NMR provides a digest of the current literature, compiled by experts in the field. The current volume devotes several chapters to the aspects and applications of spin-spin couplings, and biochemists will find seperate chapters dedicated to proteins, lipids and carbohydrates. Further chapters discuss the latest developments in nuclear sheilding, imaging and NMR in living systems. For a comprehensive account of the latest developments and research using NMR, look no further than Specialist Periodical Reports - Nuclear Magnetic Resonance. An essential book for NMR lab and university shelf.

Medicinal Plants

Author: Parimelazhagan Thangaraj
Publisher: CRC Press
ISBN: 1351046497
Size: 66.13 MB
Format: PDF, ePub, Mobi
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This book highlights the importance of traditional medicines, focuses on the standardization of herbal medicine and evaluates opportunities for advancing drug research. It addresses issues in utilization of medicinal plants and shares the importance of herbs in neutraceutics. It provides most competitive techniques being used in research.

Research Guidelines For Evaluating The Safety And Efficacy Of Herbal Medicines

Author: World Health Organization. Regional Office for the Western Pacific
Publisher: World Health Organization
ISBN: 9789290611103
Size: 45.61 MB
Format: PDF, ePub, Docs
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Sets out detailed guidelines for conducting scientific research on the safety and efficacy of herbal medicines. The guidelines which reflect the consensus reached by 17 experts in pharmacology biochemistry and traditional medicine respond to the need to assure the safety of widely-used herbal medicines while also facilitating the search for new pharmaceutical products. Specific research criteria are covered together with general principles of investigation including ethical concerns. The book has three parts. The first discusses the special properties of herbal medicines that need to be considered when designing research protocols. The second part provides detailed guidance on the objectives of research the contents of a research protocol and the methods of investigation for non-clinical studies and for Phase I to Phase IV clinical trials. The third part which forms the core of the book presents three sets of research guidelines: for quality specifications of plant materials and preparations for pharmacodynamic and general pharmacological studies of herbal medicines and for toxicity investigation of herbal medicines. Topics covered range from the information required to establish the identity and quality of plant materials or preparations through the selection of appropriate test systems for pharmacodynamic studies to detailed advice on the many different tests examinations observations and experimental procedures required in experimental animals and controls to establish the safety of herbal medicines. The guidelines are intended to facilitate the work of research scientists and clinicians while also furnishing some reference points for the governmental industrial and non-profit organizations providing financial support.

Evidence Based Validation Of Herbal Medicine

Author: Pulok K. Mukherjee
Publisher: Elsevier
ISBN: 0128009969
Size: 56.84 MB
Format: PDF, ePub, Mobi
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Evidence-Based Validation of Herbal Medicines brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on describing the full range of evidence-based analytical and bio-analytical techniques used to characterize natural products, including –omic technologies, phyto-chemical analysis, hyphenated techniques, and many more. Includes state-of-the-art methods for detecting, isolating, and performing structure elucidation by degradation and spectroscopic techniques Covers biosynthesis, synthesis, and biological activity related to natural products Consolidates information to save time and money in research Increases confidence levels in quality and validity of natural products

Traditional Medicine In Asia

Author: Ranjit Roy Chaudhury
Publisher:
ISBN: 9789290222248
Size: 12.48 MB
Format: PDF
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This unique book provides a comprehensive picture of the vivid kaleidoscope of traditional medicine in Asia presented by 34 eminent authors from 15 countries belonging to the different systems like Ayurveda and Chinese Traditional Medicine. Important emerging areas such as harmonization of the traditional systems with modern medicine and the growing role of these systems in the health care structure of countries are also dealt with. Legislation and regulation of these systems and practitioners, an area of growing concern, the need for good preclinical toxicology studies and scientific clinical evaluation of the products and medicinal plants used for therapy are exhaustingly dealt with. The vital issue of protection of traditional systems of medicine and patenting of medicinal plants is discussed in detail. The book is replete with suggestions, and ideas aimed at making traditional systems more effectively, and more widely used for health care. The book also covers the prevailing situation regarding the use and other aspects of traditional medicine in the 10 Member countries of the South-East Asia Region of the World Health Organization.

Greco Arab And Islamic Herbal Medicine

Author: Bashar Saad
Publisher: John Wiley & Sons
ISBN: 9781118002261
Size: 53.42 MB
Format: PDF, ePub, Docs
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This book presents a systematic review on traditional Arab herbal medicine including historical background, medical innovations introduced by Arab physicians, common roots of Arab medicine and western medicine, methodology of drug discovery and therapy in Arabic and Islamic medicine, a state-of-the-art description of traditional Arab herbal medicine, and evidence-based safety and efficacy of Arab and Islamic medicines. The usage of modern cell biological, biochemical, in vitro and in vivo techniques for the evaluation of medicinal plant safety and efficacy is also discussed. The toxicity of herbal formulations safety, quality assurances, and chemical analytical techniques are introduced in this book.

Essentials Of Botanical Extraction

Author: Subhash C. Mandal
Publisher: Academic Press
ISBN: 0128025638
Size: 59.63 MB
Format: PDF, ePub
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Essentials of Botanical Extraction: Principles and Applications provides a unique, single source of valuable information on the various botanical extraction methods available, from conventional to the use of green and modern extraction technologies including ultrasounds, microwaves, pressurized liquids, and supercritical fluids. Most extracts obtained from botanicals are often poorly characterized with unidentified active or inactive constituents. A wise selection of an extraction strategy is vital to drug discovery from medicinal plants as extraction forms the basic first step in medicinal plant research. This book also explores the mathematical hypotheses and innovations in botanical extractions and analyzes different post extraction operations so that dependency on serendipity is reduced and the same be converted into programmed drug discovery. Reviews the history and current state of natural product drug discovery and development, highlighting successes and current issues Explains the application of chemometric tools in extraction process design and method development Introduces process intensification as applied to the processing of medicinal plant extracts for rapid and cost-effective extraction

Medicinal Plants

Author: Hao Da
Publisher: Woodhead Publishing
ISBN: 0081001037
Size: 69.89 MB
Format: PDF, Mobi
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Medicinal Plants: Chemistry, Biology and Omics reviews the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plant tribes and genera, and their relevance to drug efficacy. Medicinal plants provide a myriad of pharmaceutically active components, which have been commonly used in traditional Chinese medicine and worldwide for thousands of years. Increasing interest in plant-based medicinal resources has led to additional discoveries of many novel compounds, in various angiosperm and gymnosperm species, and investigations on their chemotaxonomy, molecular phylogeny and pharmacology. Chapters in this book explore the interrelationship within traditional Chinese medicinal plant groups and between Chinese species and species outside of China. Chapters also discuss the incongruence between chemotaxonomy and molecular phylogeny, concluding with chapters on systems biology and “-omics technologies (genomics, transcriptomics, proteomics, and metabolomics), and how they will play an increasingly important role in future pharmaceutical research. Reviews best practice and essential developments in medicinal plant chemistry and biology Discusses the principles and applications of various techniques used to discover medicinal compounds Explores the analysis and classification of novel plant-based medicinal compounds Includes case studies on pharmaphylogeny Compares and integrates traditional knowledge and current perception of worldwide medicinal plants