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Viral Pathogenesis And Immunity

Author: Neal Nathanson
Publisher: Elsevier
ISBN: 9780080471051
Size: 58.18 MB
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Based on the highly successful reference work Viral Pathogenesis published in 1997, this concise, economical version can be used both as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy in a format that is easy to understand without continually referring to additional information. Used by the author in his graduate classes at the University of Pennsylvania, it sets forth the essential principles and discusses the details of how the immune system responds to viral invasion including the treatment and prevention of infection. Illustrated by pertinent examples it is one of the only books devoted exclusively to this topic. * Offers almost a 20% expansion over the first edition * Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic * Neal Nathanson is one of the primary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virology and Topley and Wilson's Microbiology * Now in four color throughout!

Viral Pathogenesis

Author: Michael G. Katze
Publisher: Academic Press
ISBN: 0128011742
Size: 77.40 MB
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Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. Covers all aspects of viral infection, including viral entry, replication, and release, as well as innate and adaptive immunity and viral pathogenesis Provides a fresh perspective on the approaches used to understand how viruses cause disease Features molecular profiling techniques, whole genome sequencing, and innovative computational methods Highlights the use of contemporary approaches and the insights they provide to the field

West Nile Encephalitis Virus Infection

Author: Michael S. Diamond
Publisher: Springer Science & Business Media
ISBN: 9780387798400
Size: 23.68 MB
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West Nile virus is a neurotropic flavivirus that has emerged globally as a primary cause of viral encephalitis. Infection of humans and other vertebrate animals is associated with a febrile illness that can progress to a lethal encephalitis or flaccid paralysis syndrome. Its appearance in the Western Hemisphere in 1999 and the corresponding increase in global disease burden over the last decade have been accompanied by intensive study, including the entry of many scientists into the field. Breakthroughs have been made in understanding the unique transmission pattern between the vector and the multiple avian and mammalian hosts and targets. Studies in mammalian systems have dissected the viral and host factors that determine the pathogenesis and outcome of West Nile virus infection. On the basis of these experiments, progress has been made on the identification of genetic factors that predispose to severe human disease. Thus, in a remarkably short period of time, insight has been gained on a wide variety of disciplines related to West Nile virus biology. The aim of this book was to assemble an up-to-date and cutti- edge anthology from the leading experts in the field. The chapters are balanced by submissions from newcomers who have made significant recent contributions with those from established investigators who have dedicated their careers to the study of West Nile virus.

Molecular Pathogenesis Of Virus Infections

Author: P. Digard
Publisher: Cambridge University Press
ISBN: 9780521832489
Size: 20.50 MB
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This symposium book covers the central factors that influence the pathogenicity of virus and prion infections. Virus and prion diseases remain a major public health threat, in both developed and developing countries. The worldwide HIV pandemic is one example of a newly emerged virus disease, and older human viruses such as influenza, papilloma, and the hepatitis viruses still cause major health problems. Some viruses may also establish persistent infections which can lead to the development of chronic diseases, including cancer.

The Flaviviruses

Author: Thomas J. Chambers
Publisher: Elsevier
ISBN: 0120398605
Size: 14.11 MB
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Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts. * Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions. * New, detailed information on the pathogenesis and immunology of the Flavivirus family. * Descibes the technologies that have contributed to our current knowledge about the Flaviviruses. * Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease. * An exhaustive compendium of current and past knowledge on the Flavivirus family

Handbook Of Human Stress And Immunity

Author: Ronald Glaser
Publisher: Academic Press
ISBN: 1483295125
Size: 52.99 MB
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In 1964, George Solomon coined the term psychoneuroimmunology. In the intervening 30 years, this term has emerged into a dynamic field of study which investigates the unique interactions between the nervous, endocrine, and immune systems. The Handbook of Human Stress and Immunity is a comprehensive reference for this dynamic new field. Focusing on how stressors impact the central nervous system and the resulting changes in immune responses, the Handbook is the first to describehow stress specifically affects human immune systems. It discusses how stress generally makes people more susceptible to infection, how personal support systems can counteract the physiological effects of stress, and how stress, or lack of stress, affects the aging process. Chapters are authored by the leading names in the field and cover such diseases as autoimmune disease, viral pathogenesis, herpes, HIV, and AIDS.

Viral Immunity

Author: J. E. Williams
Publisher: Hampton Roads Publishing
ISBN: 9781612830407
Size: 80.73 MB
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HIV, hepatitis, influenza, the common cold, herpes, Ebola, Hantavirus, West Nile fever, dengue, TT virus--the viral world keeps posing new major challenges to human health each year. At the same time as this onslaught of emerging powerful viral infections, our antibiotic arsenals are losing ground and our immune systems are compromised. Can we handle the next viral epidemic? Yes, says James Williams, an experienced, credentialled naturopath, acupuncturist, and expert in traditional Chinese medicine. We can shore up our immune system to handle current and any future viral infections and not be dependent on conventional vaccinations or antibiotics to insure our health. In 10 practical steps, Dr. Williams shows how to develop unassailable viral immunity using natural approaches. If you already have a viral infection, these steps will help you reverse its effects; if you're concerned about exposure to one in the future, these steps will give you the keys to prevention. Included in these steps are the best that natural medicine offers: stress management, enzymes, nutrients, detoxification, oxygen therapy, immune modulators, hormones, natural antiviral medicines and anti-inflammatory medicines, Chinese and Western herbs, and more. "Viral immunity is without question one of the most important health issues of this century," says Dr. Williams. "The message of this book is clear. You can improve your system in general with diet, lifestyle, and natural medicines. Here you will find natural ways of improving immune function, remedies to treat viral infections, and suggestions on how to reframe outdated concepts that could otherwise prevent you from obtaining effective treatment."

Hiv And The New Viruses

Author: Angus G. Dalgleish
Publisher: Elsevier
ISBN: 9780080534084
Size: 31.28 MB
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HIV and the New Viruses presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time. These cover recently discovered viruses such as HHV-6, HHV-8 and HCV, as well as the latest research on HIV. This comprehensive and updated reference includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses and management of conditions associated with those viruses. Information on new pharmaceuticals and vaccine developments is also included. Edited by the leading experts in the field, HIV and the New Viruses will be essential reading for postgraduates, clinicians and researchers in virology, immunology, cancer, molecular biology and the pharmaceutical industry. Presents cutting-edge reviews of persistent human virus infections as a coherent collection for the first time Includes an in-depth study of the major issues in the epidemiology, pathogenicity, molecular virology, host responses, and management of conditions associated with those viruses

Practical Guidelines In Antiviral Therapy

Author: G.J. Galasso
Publisher: Elsevier
ISBN: 9780080539379
Size: 46.30 MB
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This text was developed with the practicing physician in mind, however, it will be of considerable interest to the virologist, pharmacologist, chemist and all scientists interested in antiviral agents. Progress in the field of antiviral development is now moving rapidly and there is hope that one day there will be successful treatment modalities for most viral diseases. This work contains contributions from experts around the world, capturing worldwide practices. An online version providing the current status of antiviral research is planned for the near future.

The Immune Response To Viral Infections

Author: B.A. Askonas
Publisher: Springer Science & Business Media
ISBN: 1468457128
Size: 35.74 MB
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Virus diseases continue to represent serious health problems in most parts of the world. In spite of the fact that diseases such as polio myelitis and measles have been controlled in the industrialized countries by vaccination, vaccines now in use in tropical countries have proved not to be optimal. Further research is needed to develop new vaccines that will be effective in all countries. To do so we need to understand better the immune response to different viruses so that we may be able to maxi mize the protective response of new vaccines and minimize their potential immunopathologic effect. An exciting new discovery which is now being further developed is the possibility of being able to use some viruses (e.g. vaccinia, adenoviruses, etc.), as carriers for other antigens. This may open up the way for the production of vaccines that will be inexpensive and that will confer long lasting immunity after only one injection. This meeting has also served to review our present knowledge of virus diseases which are still of great importance such as hepatitis, dengue and influenza.